El embarazo es la única causa natural de inmunización contra el sistema de Antígenos Leucocitarios Humano (HLA). Durante la gestación hay paso de leucocitos fetales a través de la placenta, lo que puede desencadenar en la madre una respuesta inmunológica contra los antígenos HLA fetales de origen ...
Méndez-Rayo, Tatiana;
Posso-Osorio, Iván;
Nieto-Aristizábal, Ivana;
Aragón, Cristian C;
Naranjo-Escobar, Juan;
Ruiz-Ordoñez, Ingrid;
Echeverri, Alex;
Castaño, Gloria L;
Cañas, Carlos A;
Castillo, Carmen M;
Tobón, Gabriel J.
ABSTRACT Introduction: Lupus nephritis (LN) is one of the most prevalent and severe complications of systemic lupus erythematosus (SLE), requiring reliable urine and serum biomarkers to evaluate it. Anti-nucleosome and anti-C1q antibodies are associated with LN in several geographic regions. Also, sout...
INTRODUCCIÓN: La epilepsia es un desorden neurológico crónico caracterizado por crisis convulsivas recurrentes, y constituye uno de los trastornos neurológicos con mayor prevalencia global. Una de las etiologías que ha cobrado mayor relevancia en el último tiempo es la autoinmunidad, la que ha veni...
Erramuspe, C;
Racca, M;
Siemsen, M;
Pelosso, M;
Quaglia, M;
Tissera, Y;
Alonso, C;
Savio, V;
Albiero, J;
Gobbi, C;
Alba, P;
Boffelli, L;
Maccioni, M;
Demarchi, M.
Introducción: El interferón (IFN) tipo I es una citoquina que juega un rol fundamental en la patogenia del Lupus Eritematoso Sistémico (LES). Diferentes niveles de esta citoquina podrían explicar la heterogeneidad de esta patología y ser útil para evaluar la actividad de la misma. Objetivos: Determ...
ABSTRACT Programmed cell death protein 1 (PD-1) and its ligand, programmed death-ligand-1 (PD-L1), play key roles in the suppression of the cytotoxic activity of T cells. PD-L1 is overexpressed on various types of cancer cells, leading to immune evasion. In the past decade, therapeutic antibodies that ta...
Freire, Bianca;
Souza, Fabiola;
Curci, Vera Cláudia Lorenzetti Magalhães;
Mateus, Gustavo Pavan;
Marini, Adilson;
Oliveira, Solange de;
Romaldini, Adriana Hellmeister de Campos Nogueira;
Stefano, Eliana de;
Shimozako, Helio;
Okuda, Liria Hiromi.
The present research evaluated the seroprevalence of anti-zika virus (anti-ZIKV) antibodies by virus neutralization test (VNT) in 529 bovines from Andradina city, São Paulo state, Brazil. The reading was performed in an inverted optical microscope, considering reagents when the antibodies were capable t...
Castiglioni, Lilian;
Aires, Luiz Paulo Nogueira;
Ferrari, Vinícius Matheus;
Murata, Fernando Henrique Antunes;
Soares, Herbert Sousa;
Gennari, Solange Maria;
Machado, Juliana Giantomassi;
Fracischetti, Adriana Santiago;
Sartori, Ricardo Quitério;
Mattos, Luiz Carlos de;
Brandão, Cinara Cássia;
Pena, Hilda Fátima Jesus.
Toxoplasmosis is a protozoonosis caused by an obligate intracellular parasite named Toxoplasma gondii, which can infect humans and a large number of homeothermic animal species with worldwide distribution. The present study aimed to detect anti-T. gondii antibodies from serological samples of free-livin...
Several pathogens and antibodies derived from serum or produced in tissues associated with the oral cavity are present in the oral fluid (OF). Considering the applicability of this alternative sample, recent studies in veterinary medicine have tested OF as a replacement for serum in diagnostic assays. Th...
Introducción: Las bases fisiopatológicas del Síndrome de ovario poliquístico pueden predisponer a mayor riesgo de autoinmunidad a las mujeres que tienen esta condición y existen evidencias, aunque escasas, de mayor prevalencia de autoinmunidad tiroidea en ellas. Objetivos: Determinar la frecuenci...
