Abstract Several factors contribute to the resistance of some pathogenic microorganisms and this fact requires the search for new therapeutic alternatives. The genus Cyperus (family Cyperaceae) groups species that present chemical compounds of pharmacological interest, mainly with antimicrobial action. ...
Araújo, Aurigena Antunes de;
Silva, Edna Maria;
Mafra, Cristiane Assunção da Costa Cunha;
Costa, Íris do Céu Clara;
Barbalho, Amanda Lanna Andrade;
Matos, Iolanda Augusta Fernandes de;
Santos, Matheus Araujo dos;
Lopes, Maria Luiza Diniz de Sousa;
Medeiros, Caroline Addison Carvalho Xavier de;
Soares, Luiz Alberto Lira;
Machado, Janaina Carla Barbosa;
Ferreira, Magda Rhayanny Assunção;
Araújo, Raimundo Fernandes de;
Nascimento, Rubens Maribondo do;
Guerra, Gerlane Coelho Bernardo.
Abstract Curcumin, contained at Turmeric (Curcumalonga), can exert many beneficial pleiotropic activities in the gastrointestinal tract. This study evaluated the antioxidant and anti-inflammatory activity of C. longa on 5-fluorouracil (5-FU)-induced oral mucositis (OM) in hamsters. Phytochemical analysi...
Abstract This study assessed the inhibitory potential of the probiotics Lactobacillus (LB) exopolysaccharides (EPS) with or without extracts of Satureja calamintha on enteropathogenic Escherichia coli (EPEc) responsible for gastroenteritis. Methanolic and hydromethanolic extracts were prepared by cold ma...
Andrade, João Paulo Campos;
Alves, Osvaine Junior Alvarenga;
Costa, Marian Caroline;
Gimenez, Valéria Maria Melleiro;
Squarisi, Iara Silva;
Nicolella, Heloiza Diniz;
Pagotti, Mariana Cintra;
Tavares, Denise Crispim;
Cunha, Wilson Roberto;
Silva, Márcio Luís Andrade e;
Januario, Ana Helena;
Magalhães, Lizandra Guidi;
Pauletti, Patrícia Mendonça.
Abstract Adenocalymma axillarum (K.Schum.) L.G. Lohmann is a liana belonging to the family Bignoniaceae. In traditional medicine, the genus Adenocalymma is used to treat fever, skin ailments, and body, joint, and facial muscle pains, and it is also applied as cosmetic. Biological assays conducted with th...
Abstract Pharmacokinetic studies were carried out in male and female rats to quantify silymarin as silybin (A+B) after the oral administration of various silymarin formulations combined with three bioenhancers, namely, lysergol, piperine, and fulvic acid, and compared with plain silymarin formulation (co...
Abstract Lysiphyllum strychnifolium (Craib) A. Schmitz. (in Thai name, Ya nang daeng) has been traditionally used to treat fever, alcohol intoxication, cancer, allergies, and blood toxins. It can be used as a health-promoting herbal tea and contains hydroalcoholic extracts. The purpose of the present stu...
Abstract The illicit market of counterfeit medicines containing sildenafil and tadalafil has been causing serious public health problems. Thus, further studies on this illicit association are needed. A stability-indicating HPLC method was developed for simultaneous determination of tadalafil (TAD) and si...
Abstract Flavonoids display various beneficial biological properties, such as antioxidant activity and low cytotoxicity, which make them useful ingredients in foods, pharmaceuticals, and functional cosmetics. In particular, dihydroquercetin (DHQ) is found in various forms, and its derivatives exhibit int...
Antioxidantes/efectos adversos,
Acetatos/administración & dosificación,
Alimentos/clasificación,
Concentración 50 Inhibidora,
Cosméticos/clasificación,
Cromatografía Líquida de Alta Presión/métodos,
Espectrometría de Masas/métodos,
Espectroscopía de Resonancia Magnética con Carbono-13,
Flavonoides/antagonistas & inhibidores,
Preparaciones Farmacéuticas,
Informe de Investigación,
Pruebas de Sensibilidad Microbiana
Abstract In the present study, free interstitial levels reached by metformin in the liver were investigated in control and diabetic rats by microdialysis. Firstly, a bioanalytical method using an HPLC-UV system to determine the drug concentration in microdialysis samples was validated. The blood glucose ...
Abstract The main aim of the study is to quantify the cytotoxic property of the Fucoidan extracted from the Turbinaria conoides using the MTT assay with the standard fucose. Fucoidan was extracted using the soaked water method and it was determined using the HPLC procedure the obtained Test sample Fucoid...
Técnicas In Vitro/instrumentación,
Células MCF-7,
Células A549,
Citotoxinas/efectos adversos,
Cromatografía Líquida de Alta Presión/métodos,
Concentración 50 Inhibidora,
Fibroblastos/clasificación,
Fucosa/análogos & derivados,
Línea Celular,
Neoplasias Pulmonares/patología,
Neoplasias de la Mama/patología
