Summary Introduction: Cryptorchidism is a common and prevalent condition in patients with Down syndrome. Environmental factors, such as smoking, can be associated with malformations during fetal development. The study of the prevalence of cryptorchidism and its association with parental tobacco use in D...
Abstract Background: The dietary limitation during pregnancy influences the growth and development of the fetus and offspring and their health into adult life. The mechanisms underlying the adverse effects of gestational protein restriction (GPR) in the development of the offspring hearts are not well u...
Abstract Objective: Autism spectrum disorders are lifelong and often devastating conditions that severely affect social functioning and self-sufficiency. The etiopathogenesis is presumably multifactorial, resulting from a very complex interaction between genetic and environmental factors. The dramatic i...
ABSTRACT CONTEXT AND OBJECTIVE: Smoking during pregnancy is an important risk factor for maternal and infant health that is preventable. This study aimed to investigate the risk factors associated with smoking behavior during pregnancy. DESIGN AND SETTING: A household-based probability sample survey ...
Gestational diabetes mellitus (GDM) is one form of diabetes affect approximately 7 % of pregnancies. Diabetic peripheral neuropathy (DPN) is a common complication of diabetes that is associated with loss of nerve fibers, myelin abnormalities and significant decrease in the expression of myelin basic prot...
ABSTRACT The aim of this study was to compare two models of swimming applied to pregnant rats born small for pregnancy age (SPA). Diabetes was chemically induced in adult female rats to develop an inadequate intrauterine environment, leading to birth of a SPA offspring. In adulthood, the female SPA rats ...
Animales Recién Nacidos/fisiología,
Glucemia/análisis,
Glucemia/metabolismo,
Peso Corporal/fisiología,
Diabetes Mellitus Experimental/metabolismo,
Diabetes Mellitus Experimental/fisiopatología,
Desarrollo Fetal/fisiología,
Retardo del Crecimiento Fetal/metabolismo,
Retardo del Crecimiento Fetal/fisiopatología,
Prueba de Tolerancia a la Glucosa,
Modelos Animales,
Condicionamiento Físico Animal/métodos,
Condicionamiento Físico Animal/fisiología,
Efectos Tardíos de la Exposición Prenatal/metabolismo,
Efectos Tardíos de la Exposición Prenatal/fisiopatología,
Distribución Aleatoria,
Ratas Wistar,
Valores de Referencia,
Natación/fisiología,
Factores de Tiempo
Intrauterine growth retardation (IUGR) is associated with the development of adult-onset diseases, including pulmonary hypertension. However, the underlying mechanism of the early nutritional insult that results in pulmonary vascular dysfunction later in life is not fully understood. Here, we investigate...
Modelos Animales de Enfermedad,
Retardo del Crecimiento Fetal/etiología,
Retardo del Crecimiento Fetal/metabolismo,
Hipoxia Fetal/complicaciones,
Hipoxia Fetal/fisiopatología,
Técnica del Anticuerpo Fluorescente,
Hipertensión Pulmonar/etiología,
Hipertensión Pulmonar/patología,
Hipertensión Pulmonar/fisiopatología,
Immunoblotting,
Inmunohistoquímica,
Canal de Potasio Kv1.5/análisis,
Desnutrición/complicaciones,
Músculo Liso Vascular/química,
Músculo Liso Vascular/patología,
Organofosfatos/metabolismo,
Fosforilación,
Polímeros/metabolismo,
Efectos Tardíos de la Exposición Prenatal/metabolismo,
Arteria Pulmonar/patología,
Arteria Pulmonar/fisiopatología,
ARN Mensajero/análisis,
Distribución Aleatoria,
Ratas Sprague-Dawley,
Reacción en Cadena en Tiempo Real de la Polimerasa,
Factores de Tiempo,
Regulación hacia Arriba
Previous study has shown the adverse effects of gestational diabetes on hippocampal and spinal cord neuronal density in animal model. This study was conducted to determine the effect of gestational diabetes on beta cells in rat pancreas in early postnatal life. In this experimental study, 10 dams randoml...
RESUMO Objetivo Identificar os efeitos da ingestão de álcool na gestação sobre o sistema nervoso auditivo central em relação aos seus possíveis diagnósticos, Síndrome Fetal do Álcool, Síndrome Fetal do Álcool Parcial, Distúrbios ao Nascimento Relacionados ao Álcool e Distúrbio do Neurodes...
Consumo de Bebidas Alcohólicas/efectos adversos,
Percepción Auditiva,
Electrofisiología,
Potenciales Evocados Auditivos,
Potenciales Evocados Auditivos del Tronco Encefálico,
Enfermedades Fetales/diagnóstico,
Enfermedades Fetales/etiología,
Enfermedades Fetales/fisiopatología,
Trastornos de la Audición/inducido químicamente,
Trastornos de la Audición/diagnóstico,
Trastornos de la Audición/fisiopatología,
Efectos Tardíos de la Exposición Prenatal/diagnóstico,
Efectos Tardíos de la Exposición Prenatal/etiología,
Efectos Tardíos de la Exposición Prenatal/fisiopatología
OBJECTIVES: Considering that changes in the maternal environment may result in changes in progeny, the aim of this study was to investigate the influence of sleep restriction during the last week of pregnancy on renal function and autonomic responses in male descendants at an adult age. METHODS: After c...
Sistema Nervioso Autónomo/fisiopatología,
Barorreflejo/fisiología,
Presión Sanguínea/fisiología,
Modelos Animales de Enfermedad,
Desarrollo Fetal/fisiología,
Análisis de Fourier,
Tasa de Filtración Glomerular,
Frecuencia Cardíaca/fisiología,
Hipertensión/etiología,
Hipertensión/fisiopatología,
Riñón/fisiopatología,
Enfermedades Renales/etiología,
Enfermedades Renales/fisiopatología,
Efectos Tardíos de la Exposición Prenatal/etiología,
Efectos Tardíos de la Exposición Prenatal/fisiopatología,
Distribución Aleatoria,
Ratas Wistar,
Factores de Riesgo,
Privación de Sueño/complicaciones,
Privación de Sueño/fisiopatología,
Factores de Tiempo
