Results: 388

Polystyrene-b-poly (acrylic acid) nanovesicles coated by modified chitosans for encapsulation of minoxidil

Abstract In this work, polystyrene-b-poly (acrylic acid) (PS-b-PAA) nanovesicles were coated by modified chitosans aiming at studying its physicochemical parameters. The chitosan (CS) was chemically modified to add hydrophilic and/or hydrophobic groups, obtaining three modified chitosans. The PS-b-PAA n...

Interações entre o relógio biológico e a sinalização do estado energético em plantas do complexo Saccharum

A cana-de-açúcar e a cana energia são plantas intercruzáveis que compõe o complexo Saccharum. Estas plantas são fonte de biomassa para produção de açúcar, biocombustíveis, eletricidade, entre outros, e utilizam a energia assimilada pela fotossíntese de forma contrastante, ainda que ambas resu...

Novel biopharmaceutical development investigations towards drug and formulation performance optimization

For a drug to excerpt pharmacological action after oral intake, it first needs to be released from the formulation, get into solution (dissolve), be absorbed, and reach the systemic circulation. Since only solubilized drugs can be absorbed, and thus have therapeutic effect, the understanding of the disso...

99m Technetium-HMPAO-labeled platelet scan in practice: Preparation, quality control, and biodistribution studies

Abstract There is no biodistribution or imaging data on 99mtechnetium (Tc)-hexamethyl propylamine oxime (HMPAO)-labeled platelets in the literature. The current study aimed to present updated information about the clinical procedures for preparation and use of labeled platelets. Following two-step centri...

Formulation of stomach-specific floating microparticles of nizatidine and their radiographic evaluation

Nizatidine is an anti-secretogogue and a gastroprotective drug with a half-life of 1-2 h and is well absorbed in the stomach. This study aimed to optimize the process and develop floating microparticles of nizatidine that are based on low methoxyl pectin. Oil-in-oil dispersion method and Taguchi orthogon...

Productivity costs associated to voice symptoms, low sleep quality, and stress among college professors during homeworking in times of COVID-19 Pandemic

Objective. To estimate the productivity reduction costs associated to self-reported voice symptoms, low sleep quality, and high stress levels among college professors during homeworking in times of COVID-19 pandemic. Methods. This cross-sectional study included fifty-eight college professors...

Uso não prescrito de metilfenidato e desempenho acadêmico de estudantes de medicina

Psicol. ciênc. prof; 42 (), 2022
O metilfenidato é um fármaco indicado no tratamento do transtorno de déficit de atenção e hiperatividade (TDAH) e da narcolepsia. Atua no sistema nervoso central inibindo a recaptação de dopamina e noradrenalina, o que provoca um efeito psicoestimulante. Estudos anteriores demonstraram um aumento ...

An analysis of temporal numerical superiority in the pan-american junior men's water polo matches

ABSTRACT This study compared the frequency, number of goals and attack efficiency in temporal numerical superiority among winning and losing teams and among balanced and unbalanced matches in a junior men's water polo competition. Another analysed relationship was that between a balanced or unbalanced fi...

Running performance of non-professional female runners from different Brazilian states: the role of environmental characteristics

Motriz (Online); 28 (), 2022
Abstract Aims: (i) to compare the running performance of non-professional female runners from different Brazilian states; (ii) to estimate the relationship between environmental state-related variables and running performance; and (iii) to analyze the mediation role of training commitment in the relatio...

High-intensity effort impairs basketball free-throw shooting efficiency

Motriz (Online); 28 (), 2022
Abstract Aim: This study verified how much performance damage can high-intensity efforts cause to FT shooting efficiency. Methods: A sample of 13 male amateur basketball players (19.9 ± 3.2 years; 76.7 ± 8.7 kg; 182 ± 10 cm) participated in the study on three non-consecutive days. A maximum progress...