Abstract Salidroside (SAL) has been confirmed to have some protective effects against inflammatory injury. However, little information was established as to the mechanism of these protective effects. To this effect, we designed this study to explore the protective effects and mechanisms of SAL against my...
SUMMARY: In Saudi Arabia, it is widely believed that women with reproductive problems can use the extract of the sage plant as a tea drink. This study was conducted to investigate the effects of this herb on the fertility of female rats and embryo implantation. Forty-eight Wistar virgin female rats were ...
El hiperaldosteronismo primario (HAP) es la causa más común de hipertensión arterial secundaria. A pesar de la prevalencia del HAP (6-10%) y sus consecuencias, los mecanismos que median los efectos deletéreos renales y extrarenales originados por la aldosterona más allá de la hipertensión arterial...
Hiperaldosteronismo/diagnóstico,
Biomarcadores/sangre,
Orosomucoide/análisis,
Estudios Transversales,
Estudios de Cohortes,
Hipertensión/diagnóstico,
Lipocalinas/análisis,
Presión Arterial,
Hiperaldosteronismo/sangre,
Lipocalinas/sangre,
Aldosterona/sangre,
Renina/análisis,
Ensayo de Inmunoadsorción Enzimática
Abstract In China, Scutellaria is used for treating inflammatory-related diseases. Baicalin is the main active component of Scutellaria and has protective effects on acute pancreatitis. However, the mechanism of Baicalin is still unclear. In this study, the protective effects of baicalin on acute pancrea...
Braga, Tatiane Vieira;
Evangelista, Fernanda Cristina Gontijo;
Santiago, Marie Gabriele;
Ferrão, Aline Lúcia Menezes;
Almeida, Tamara Dauare de;
Barbosa, Bárbara Lima da Fonseca;
Araujo, Sergio Schusterschitz da Silva;
Ribeiro, Glaciano Nogueira;
Carvalho, Maria das Graças;
Sabino, Adriano de Paula.
Chronic lymphocytic leukemia (CLL) is a blood cancer characterized by the accumulation of clonal B-lymphocytes. This study evaluated the mRNA gene expression of miR-15a, miR-16- 1, ZAP-70, and Ang-2 by qPCR, as well as the plasma levels of Bcl-2 by Elisa immunoassay, in CLL patients and healthy controls....
Abstract In an attempt to increase molecular stability and provide controlled release, vascular endothelial growth factor (VEGF) was encapsulated into polycaprolactone (PCL) nanoparticles. Both VEGF-free and VEGF-loaded PCL nanoparticles were formulated by w/o/w double emulsion of the dichloromethane-wat...
Abstract To explore the effects and mechanisms of benzoylaconitine and paeoniflorin on collagen-induced arthritis (CIA) rats. Weight, paw swelling, arthritis index and joint pathologic changes were examined in each group after CIA induction. PGE2, IL-1β, IL-6, IL-10, TNF-α, VEGF, MMP-3, IgG and anti-CI...
INTRODUCCIÓN: La pandemia de COVID-19 surgida en China a fines de 2019, se extendió rápidamente por el mundo, con casi 600 millones de casos y 6,3 millones de fallecidos en la actualidad. Los más afectados fueron los trabajadores de la salud con al menos tres veces más riesgo que la comunidad genera...
Personal de Salud,
COVID-19/epidemiología,
SARS-CoV-2/inmunología,
Atención Primaria de Salud,
COVID-19/inmunología,
Estudios Seroepidemiológicos,
Estudios Transversales,
Inmunoglobulina G/análisis,
Ensayo de Inmunoadsorción Enzimática,
Prevalencia,
Encuestas y Cuestionarios,
Factores de Riesgo,
Chile/epidemiología,
Anticuerpos Antivirales
Ferreira-Silva, Márcia M;
Pereira, Gilberto de Araújo;
Rodrigues-Júnior, Virmondes;
Meira, Wendell SF;
Basques, Fernando V;
Langhi-Júnior, Dante Mário;
Romanelli, Marcelo;
Umezawa, Eufrosina S;
Késper-Júnior, Norival;
Louzada-Neto, Francisco;
Bordin, José O;
Moraes-Souza, Helio.
ABSTRACT Background: The screening of Trypanosoma cruzi-infected blood donors using two serological techniques frequently leads to conflicting results. This fact prompted us to evaluate the diagnostic performance of four "in-house" immunodiagnostic tests and two commercially available enzyme-linked immu...
Contar con métodos diagnósticos que reúnan ciertos atributos es vital para guiar las decisiones sanitarias, el contexto actual lo amerita. Con el objetivo de validar la capacidad de dos pruebas rápidas para detectar anticuerpos debido a la infección por SARS-CoV-2 en la Isla de la Juventud, Cuba, de...
