ABSTRACT Background: Blood transfusion-transmitted infections in individuals suffering from beta-thalassemia have been reported in Pakistan, but the information on their sociodemographic and clinical determinants is lacking. This study aims to describe the prevalence, as well as the factors, contributin...
SUMMARY OBJECTIVE The recent development of direct-acting antiviral agents (DAAs) has dramatically changed the treatment of chronic hepatitis C, and interferon-based regimes have become a poor treatment choice in clinical practice. Today DAAs offer shorter, well-tolerated, highly effective curative the...
Anilidas/uso terapéutico,
Antivirales/uso terapéutico,
Carbamatos/uso terapéutico,
Quimioterapia Combinada,
Genotipo,
Hepacivirus/efectos de los fármacos,
Hepacivirus/genética,
Hepatitis C Crónica/tratamiento farmacológico,
Hepatitis C Crónica/virologÃa,
Fallo Renal Crónico/virologÃa,
Compuestos MacrocÃclicos/uso terapéutico,
Persona de Mediana Edad,
ARN Viral/sangre,
Ribavirina/uso terapéutico,
Ritonavir/uso terapéutico,
EstadÃsticas no Paramétricas,
Sulfonamidas/uso terapéutico,
Respuesta Virológica Sostenida,
Factores de Tiempo,
Resultado del Tratamiento,
Uracilo/análogos & derivados,
Uracilo/uso terapéutico
ABSTRACT BACKGROUND: Hepatitis B and C virus (HBV and HCV) are the two most common infections among human immunodeficiency virus (HIV)-infected patients. OBJECTIVE: To identify the frequency of HIV subtypes and HCV genotypes in HIV-coinfected patients. METHODS: A cross-sectional and retrospective s...
Brasil,
Coinfección,
Estudios Transversales,
Genotipo,
Infecciones por VIH/complicaciones,
Hepacivirus/genética,
Hepatitis C/complicaciones,
Hepatitis C/virologÃa,
Persona de Mediana Edad,
Estudios Retrospectivos,
Carga Viral
Benzaken, Adele Schwartz;
Girade, Renato;
Catapan, Elisa;
Pereira, Gerson Fernando Mendes;
Almeida, Elton Carlos de;
Vivaldini, Simone;
Fernandes, Neide;
Razavi, Homie;
Schmelzer, Jonathan;
Ferraz, Maria Lucia;
Ferreira, Paulo Roberto Abrão;
Pessoa, Mario Guimarães;
Martinelli, Ana;
Souto, Francisco José Dutra;
Walsh, Nick;
Mendes-Correa, Maria Cassia.
ABSTRACT Introduction and aim: Hepatitis C is a key challenge to public health in Brazil. The objective of this paper was to describe the Brazilian strategy for hepatitis C to meet the 2030 elimination goal proposed by World Health Organization (WHO). Methods: A mathematical modeling approach was used ...
Brasil/epidemiologÃa,
Erradicación de la Enfermedad/economÃa,
Erradicación de la Enfermedad/métodos,
Genotipo,
Hepacivirus/genética,
Hepatitis C/tratamiento farmacológico,
Hepatitis C/economÃa,
Hepatitis C/epidemiologÃa,
Hepatitis C/prevención & control,
Incidencia,
Modelos Teóricos,
Organización Mundial de la Salud
Silva, Tânia Maria Pazin Marques;
Ferreto, Lirane Elize Defante;
Follador, Franciele Ani Caovilla;
Vieira, Ana Paula;
Yamada, Roberto Shigueyasu;
Lucio, Léia Carolina;
Titon, Joana Perotta;
Torres, Renata Himovski;
Amaral, Greicy Cézar do;
Coelho, Harnoldo Colares.
ABSTRACT Background: The prison system in Paraná, Brazil, is experiencing serious problems related to the increasing number of prisoners. Control of hepatitis C virus (HCV) has become more intense because the incarcerated population is considered a high-risk group for contagious diseases due to the fav...
Varón, Adriana;
Santos, Luisa;
Tapias, Mónica;
Cáez, Clara;
MarÃn, Juan Ignacio;
Santos, Óscar;
Garzón, MartÃn;
Beltrán, Óscar;
Gómez-Aldana, Andrés;
Yepes, Ismael J;
Rondón, MartÃn;
Rosselli, Diego.
There are few published real-world studies on hepatitis C in Latin America. This paper describes a cohort of Colombian subjects treated with direct-acting antiviral agents. A total of 195 patients from 5 hepatology centers in 4 Colombian cities were retrospectively studied. For each patient, serum biomar...
Antivirales/uso terapéutico,
Colombia,
Quimioterapia Combinada,
Genotipo,
Hepacivirus/genética,
Hepatitis C/tratamiento farmacológico,
Trasplante de HÃgado,
ARN Viral,
Estudios Retrospectivos,
EstadÃsticas no Paramétricas,
Respuesta Virológica Sostenida,
Carga Viral
Objetivos: La terapia ideal para la hepatitis crónica C consiste en el uso de drogas antivirales de acción directa (DAA). En el Perú la experiencia en vida real con DAA no se conoce, por lo que el objetivo del presente estudio es reportar la alta eficacia terapéutica con estos esquemas. Material y mÃ...
Antivirales/uso terapéutico,
Hepatitis C Crónica/tratamiento farmacológico,
Antivirales/administración & dosificación,
Evaluación de Medicamentos,
Quimioterapia Combinada,
Genotipo,
Hepacivirus/efectos de los fármacos,
Hepacivirus/genética,
Hepatitis C Crónica/complicaciones,
Hepatitis C Crónica/virologÃa,
Cirrosis Hepática/etiologÃa,
Cirrosis Hepática/patologÃa,
Perú,
Resultado del Tratamiento
Abstract INTRODUCTION: IgG subclasses involved in the immune response to hepatitis C virus (HCV) antigens have been rarely studied. We investigated the immune response mediated by IgG1 and IgG4 antibodies against the recombinant core and NS3 antigens in patients with chronic hepatitis C. METHODS: Six...
Alanina Transaminasa/sangre,
Estudios de Casos y Controles,
Crioglobulinemia,
Ensayo de Inmunoadsorción Enzimática,
Hepacivirus/inmunologÃa,
Anticuerpos contra la Hepatitis C/sangre,
Anticuerpos contra la Hepatitis C/inmunologÃa,
AntÃgenos de la Hepatitis C/sangre,
AntÃgenos de la Hepatitis C/inmunologÃa,
Hepatitis C Crónica/sangre,
Hepatitis C Crónica/inmunologÃa,
Inmunoglobulina G/sangre,
Cirrosis Hepática/virologÃa,
Persona de Mediana Edad,
Valores de Referencia,
EstadÃsticas no Paramétricas,
Carga Viral,
Viremia
Iintrodução: Os vÃrus linfotrópico de células T humanas (HTLV) e vÃrus da hepatite C (HCV) são endêmicos no Brasil. Ambos causam uma infecção persistente, assintomática em alguns casos, sendo o diagnóstico tardio. Estes vÃrus compartilham algumas vias de transmissão, o que pode favorecer a ...
Abstract INTRODUCTION The present study aimed to estimate the prevalence of Hepatitis C virus (HCV) infection in a prison population. METHODS: A total of 147 individuals were interviewed and subjected to venipuncture for collection of blood sample. The study population consisted of male individuals w...
