Results: 86

Serum myristic fatty acid negatively correlates with anti-inflammatory adiponectin/leptin ratio in obese adolescents: effects of long- term therapy

Mundo Saúde (Online); 40 (A), 2017
Obesity is related to metabolic disorders partially mediated by inflammatory state. In this way, adiponectin/leptin ratio is considered an anti-inflammatory biomarker related to cardiovascular risks. Evidence suggest that decrease in saturated fatty acid intake is an important dietary recommendation to r...

El hipogonadismo masculino en pacientes con diabetes tipo 2
Male hypogonadism in patients with type 2 diabetes

Circulating early biomarkers of atherogenesis in participants of the Longitudinal Study of Adult Health (ELSA-Brasil) without diabetes or cardiovascular disease

ABSTRACT Objective Our aim was to describe the distribution of selected biomarkers according to age and sex, adjusted for HOMA-IR and adiposity, in a subset of middle-aged individuals of Brazilian Longitudinal Study of Adult Health-ELSA without diabetes mellitus or CVD. Subjects and methods This cros...

Serum leptin levens and hepatocellular carcinoma: review article

ABCD (São Paulo, Impr.); 29 (4), 2016
ABSTRACT Introduction: Hepatocellular carcinoma is one of the most frequent types of malignant tumors in the world. There is growing evidence of the relationship between it development and obesity. The mechanism that links obesity to cancer is still not fully understood; however, it is essential to the ...

Alterações fisiológicas e de erupção dentária na obesidade infantil

A obesidade infantil vem crescendo e se tornando um problema mundial. Na Odontologia, em relação à obesidade infantil, já foram realizados trabalhos tentando mostrar alguma correlação entre doença cárie e doença periodontal com resultados controversos. Em relação à obesidade infantil e à eru...

Obesity, Serum Resistin and Leptin Levels Linked to Coronary Artery Disease

Arq. bras. cardiol; 107 (4), 2016
Abstract Background: Clinical studies have demonstrated that adipocytokines play an important role in developing atherosclerotic cardiovascular diseases. Objective: The aim of study was to evaluate the relationship between serum resistin and leptin levels with obesity and coronary artery disease (CAD)....

Prevalencia de comorbilidades metabólicas en pacientes con obesidad en la edad escolar y la adolescencia

Introduction: Although the International Diabetes Federation refers to the impossibility of establishing a diagnosis for metabolic syndrome in school-age patients, epidemiological data seem to suggest that such metabolic syndrome and/or its components are already present at early ages. Objective: To dete...

Seguridad y eficacia de metreleptina en el tratamiento de primera línea de pacientes con lipodistrofia generalizada congénita

INTRODUCCIÓN: Antecedentes: El Instituto de Evaluación de Tecnologías en Salud e Investigación (IETSI) ha recibido la solicitud de evaluar el uso de Metreleptina para su uso en pacientes con lipodistrofia generalizada congénita que se presentan con compromiso renal dentro del sistema de EsSalud, med...

The p. N103K mutation of leptin (LEP) gene and severe early onset obesity in Pakistan

Biol. Res; 49 (), 2016
BACKGROUND: Obesity is a complex disorder and has been increasing globally at alarming rates including Pakistan. However, there is scarce research on understanding obesity genetics in Pakistan. Leptin is a hormone secreted by adipocytes in response to satiety and correlates with body weight. Any mutation...

Disfunção cardíaca induzida por obesidade genética e dietética: modulação pelo trânsito de cálcio

Introdução: A obesidade é considerada importante problema de saúde pública e fator de risco para o desenvolvimento de doenças cardiovasculares. Estudos apontam que o trânsito de cálcio (Ca+2) intracelular e extracelular, mecanismo essencial no acoplamento excitação-contração-relax...