Abstract Objective: To discuss the recent literature on paternal obesity, focusing on the possible mechanisms of transmission of the phenotypes from the father to the children. Sources: A non-systematic review in the PubMed database found few publications in which paternal obesity was implicated in the...
Abstract Background: Different types of high-fat and/or high-energy diets have been used to induce obesity in rodents. However, few studies have reported on the effects observed at the initial stage of obesity induced by high-fat feeding on cardiac functional and structural remodelling. Objective: To c...
Presión Sanguínea,
Western Blotting,
Calcio/metabolismo,
Dieta Alta en Grasa,
Modelos Animales de Enfermedad,
Resistencia a la Insulina,
Obesidad/etiología,
Obesidad/metabolismo,
Obesidad/patología,
Obesidad/fisiopatología,
Músculos Papilares/metabolismo,
Músculos Papilares/patología,
Músculos Papilares/fisiopatología,
Distribución Aleatoria,
Ratas Wistar,
Conducta Sedentaria
ABSTRACT Objective The aim of the present study was to evaluate parameters of bone and mineral metabolism after bariatric surgery. Subjects and methods This sectional study included data from medical records from 61 bariatric surgery (BS) patients (minimum period of 6 months after the procedure) and ...
Fosfatasa Alcalina/sangre,
Aminoácidos/orina,
Desviación Biliopancreática/efectos adversos,
Remodelación Ósea/fisiología,
Huesos/metabolismo,
Calcio/orina,
Derivación Gástrica/efectos adversos,
Obesidad/tratamiento farmacológico,
Obesidad/metabolismo,
Obesidad/cirugía,
Periodo Posoperatorio,
Estudios Retrospectivos,
Sodio/orina,
Factores de Tiempo
ABSTRACT Objective To investigate the applicability of predictive equations for resting energy expenditure (REE) in obese individuals with obstructive sleep apnea (OSA) and the effects of OSA severity on REE. Materials and methods Twenty-nine obese men, 41.5 ± 7 years old, with moderate and severe O...
Algoritmos,
Análisis de Varianza,
Antropometría,
Composición Corporal/fisiología,
Calorimetría Indirecta/métodos,
Metabolismo Energético/fisiología,
Obesidad/metabolismo,
Obesidad/fisiopatología,
Polisomnografía,
Valor Predictivo de las Pruebas,
Valores de Referencia,
Reproducibilidad de los Resultados,
Descanso/fisiología,
Índice de Severidad de la Enfermedad,
Apnea Obstructiva del Sueño/metabolismo,
Apnea Obstructiva del Sueño/fisiopatología,
Factores de Tiempo
The aim of this study was to evaluate efficacy and safety of amfepramone, fenproporex and mazindol as a monotherapy for the treatment of obese or overweight patients. A systematic review of primary studies was conducted, followed by a direct meta-analysis (random effect) and mixed treatment comparison. M...
Depresores del Apetito/metabolismo,
Depresores del Apetito/uso terapéutico,
Dietilpropión/metabolismo,
Dietilpropión/uso terapéutico,
Mazindol/metabolismo,
Mazindol/uso terapéutico,
Obesidad/tratamiento farmacológico,
Obesidad/metabolismo,
Sobrepeso/tratamiento farmacológico,
Sobrepeso/metabolismo,
Sesgo de Publicación,
Reproducibilidad de los Resultados,
Factores de Riesgo,
Resultado del Tratamiento,
Pérdida de Peso/efectos de los fármacos
Abstract Obesity has been pointed out as an important cause of kidney diseases. Due to its close association with diabetes and hypertension, excess weight and obesity are important risk factors for chronic kidney disease (CKD). Obesity influences CKD development, among other factors, because it predispos...
Horn, Roberta Cattaneo;
Gelatti, Gabriela Tassotti;
Mori, Natacha Cossettin;
Tissiani, Ana Caroline;
Mayer, Mariana Spanamberg;
Pereira, Elvio Almeida;
Ross, Marcelo;
Moreira, Paulo Ricardo;
Bortolotto, Josiane Woutheres;
Felippin, Tamiris.
Summary Introduction: Obesity refers to the accumulation of fatty tissues and it favors the occurrence of oxidative stress. Alternatives that can contribute to body weight reduction have been investigated in order to reduce the production of reactive oxygen species responsible for tissue damage. The ai...
Análisis de Varianza,
Antioxidantes/análisis,
Ácido Ascórbico/sangre,
Cirugía Bariátrica/métodos,
Biomarcadores/sangre,
Estudios de Casos y Controles,
Glutatión/sangre,
Peroxidación de Lípido/fisiología,
Persona de Mediana Edad,
Obesidad/metabolismo,
Obesidad/cirugía,
Estrés Oxidativo/fisiología,
Periodo Posoperatorio,
Carbonilación Proteica/fisiología,
Especies Reactivas de Oxígeno/sangre,
Estadísticas no Paramétricas,
Sustancias Reactivas al Ácido Tiobarbitúrico/análisis
Abstract Purpose: To evaluate the effects of duodenal-jejunal bypass (DJB) on the diaphragm muscle of obese rats fed on a western diet (WD) . Methods: Eighteen male Wistar rats were fed a standard rodent chow diet (CTL group) or WD ad libitum. After 10 weeks, WD rats were submitted to sham (WD SHAM) or...
Diafragma/ultraestructura,
Dieta Occidental,
Duodeno/cirugía,
Yeyuno/cirugía,
Unión Neuromuscular/ultraestructura,
Obesidad/cirugía,
Anastomosis Quirúrgica,
Fibras Musculares Esqueléticas/ultraestructura,
Obesidad/metabolismo,
Distribución Aleatoria,
Ratas Wistar
O diabetes mellitus (DM) é uma doença metabólica complexa. Sua etiologia é
atribuída a uma combinação entre fatores genéticos, ambientais e de estilo de vida.
Contudo, sabe-se que o estresse oxidativo desempenha papel crucial na patogênese
do DM, acarretando em disfunção das células β pancre...
Modifications in life-style and/or pharmacotherapies contribute to weight loss and ameliorate the metabolic profile of diet-induced obese humans and rodents. Since these strategies fail to treat hypothalamic obesity, we have assessed the possible mechanisms by which duodenal-jejunal bypass (DJB) surgery ...
Animales Recién Nacidos,
Glucemia/metabolismo,
Proliferación Celular,
Colesterol/sangre,
Duodeno/cirugía,
Acido Graso Sintasa Tipo I/metabolismo,
Ácidos Grasos/sangre,
Hígado Graso/metabolismo,
Hígado Graso/fisiopatología,
Derivación Gástrica/métodos,
Enfermedades Hipotalámicas/metabolismo,
Enfermedades Hipotalámicas/fisiopatología,
Enfermedades Hipotalámicas/cirugía,
Insulina/22063,
Resistencia a la Insulina,
Islotes Pancreáticos/citología,
Islotes Pancreáticos/metabolismo,
Islotes Pancreáticos/fisiopatología,
Yeyuno/cirugía,
Lipogénesis/genética,
Hígado/metabolismo,
Hígado/patología,
Obesidad/metabolismo,
Obesidad/fisiopatología,
Obesidad/cirugía,
Páncreas/metabolismo,
Páncreas/patología,
Distribución Aleatoria,
Ratas Wistar,
Reproducibilidad de los Resultados,
Factores de Tiempo,
Triglicéridos/sangre
