Results: 235

miR-146a-5p-mediated suppression on trophoblast cell progression and epithelial-mesenchymal transition in preeclampsia

Biol. Res; 54 (), 2021
OBJECTIVE: This study aims to identify the effect of miR-146a-5p on trophoblast cell invasion as well as the mechanism in preeclampsia (PE). METHODS: Expression levels of miR-146a-5p and Wnt2 in preeclamptic and normal placentae were quantified. Trophoblast cells (HTR-8) were separately transfected with ...

Effects of aspirin, vitamin D3, and progesterone on pregnancy outcomes in an autoimmune recurrent spontaneous abortion model

Braz. j. med. biol. res; 54 (9), 2021
High proportions of placental lymphocytes expressing DX5+/CD25+/FOXP3+/CD45+/CD4+ are beneficial to maintain immune tolerance and improve pregnancy outcomes. This study aimed to compare and evaluate the therapeutic effects of aspirin, vitamin D3 (VitD3), and progesterone on the autoimmune recurrent spont...

Pulsatility of the umbilical cord in full-term natural childbirths

Rev. gaúch. enferm; 42 (), 2021
ABSTRACT Objective Measure umbilical cord pulsatility time and evaluate correlation/association with maternal and neonatal characteristics. Method Cross-sectional study, with 76 binomials, carried out in 2017, in a maternity hospital in Alagoas. Analysis with Pearson or Spearman correlation test and M...

Effects of vitamin D-induced supernatant of placental explants from preeclamptic women on oxidative stress and nitric oxide bioavailability in human umbilical vein endothelial cells

Braz. j. med. biol. res; 54 (8), 2021
The study evaluated the effect of the supernatant of placental explants from preeclamptic (PE) and normotensive (NT) pregnant women after tissue treatment with or without vitamin D (VD) on oxidative stress and nitric oxide (NO) bioavailability in human umbilical vein endothelial cells (HUVEC). Placental ...

Epigenetic characterization of the H19/IGF2 locus in calf clones placenta

Pesqui. vet. bras; 40 (12), 2020
Somatic Cell Nuclear Transfer (SCNT-Cloning) is a promising technique in many areas and is based on genetically identical individuals. However, its efficiency is low. Studies suggest that the leading cause is inadequate epigenetic reprogramming. This study aimed to characterize the methylation pattern of...

Árvore da vida: projeto de impressão placentária em maternidades públicas estaduais do Centro-Oeste
Tree of life: placenta printing project in public maternities in the midwest state

Enferm. foco (Brasília); 11 (5), 2020
Objetivo: relatar a experiência de residentes e enfermeiros obstétricos na implantação do projeto de impressão placentária em maternidades públicas do Estado de Goiás. Métodos: Trata-se de um relato de experiência acerca da realização de impressão placentária. A iniciativa ocorreu em Hospit...

Modelo integral de entrenamiento microquirúrgico y neuroendovascular con placenta humana
Comprehensive microsurgical and neuroendovascular training model with human placenta

Rev. argent. neurocir; 34 (4), 2020
Introducción: La neurocirugía vascular, tanto la microquirúrgica como endovascular, ha progresado significativamente en el tratamiento de la patología cerebrovascular. Sin embargo, en una considerable proporción de casos este tipo de patología no puede ser resuelta definitivamente mediante un únic...

Exposure to wood smoke pollution during pre-gestational period of rat has effects on placenta volume and fetus size

Int. j. morphol; 38 (5), 2020
SUMMARY: Studies in humans showed that prenatal exposure to urban air pollution (AP) influences fetal development, and increases the incidence of adverse pregnancy outcomes and some diseases in postnatal life. However, most of these were performed in environments where the main source of environmental pa...

Characterization of placental infection by zika virus in humans: A review of the literature

Abstract Objective The aim of the current review is to present a systematic evaluation of reported human placental findings in cases of zika virus (ZIKV) infection. Data sources We reviewed the EMBASE, PUBMED, and SCIELO databases until June 2019, without language restrictions. Selection of studies Th...

Does Enoxaparin treatment have any effects on the placenta in women with unexplained histories of habitual abortion? A case control study

Säo Paulo med. j; 138 (4), 2020
ABSTRACT BACKGROUND: It is very common to offer low molecular weight heparin (LMWH) medications to women with unexplained habitual abortion, to increase the livebirth rate. Although no benefit from LMWH has been clearly demonstrated, examination of the effects of enoxaparin on placental structure is la...