Results: 506

An open-label randomized clinical trial to evaluate the efficacy of everolimus versus tacrolimus in triple maintenance immunosuppressive therapy for kidney transplant patients

Braz. j. med. biol. res; 54 (4), 2021
Tacrolimus (TAC), a calcineurin inhibitor, and everolimus (EVL), an mTOR inhibitor, have been used as immunosuppressive (ISS) drugs in post-kidney transplantation therapy. The objective of this study was to compare the efficacy of EVL vs TAC in the ISS maintenance triple therapy. Ninety-seven kidney tran...

Safety and effectiveness of mycophenolate mofetil associated with tacrolimus for liver transplantation immunosuppression: a systematic review and meta-analysis of randomized controlled trials

Clinics; 76 (), 2021
A combination of immunosuppressants may improve outcomes due to the synergistic effect of their different action mechanisms. Currently, there is no consensus regarding the best immunosuppressive protocol after liver transplantation. This review aimed to evaluate the effectiveness and safety of tacrolimus...

Suffering among patients with cancer undergoing neurotoxic chemotherapy: a phenomenological approach

ABSTRACT Objective: reveal experiences of cancer patients undergoing neurotoxic chemotherapy. Method: phenomenology-based, qualitative study, carried out with nine adult patients in antineoplastic neurotoxic treatment, interviewed in June and July 2018. The testimonies were analyzed using an empirical ...

Diagnóstico clínico e tratamento medicamentoso em ejaculação precoce
Clinical diagnosis and drug treatment in premature ejaculation

Diagn. tratamento; 25 (4), 2020
A ejaculação precoce é um dos transtornos sexuais mais prevalentes na população masculina com prevalência média de cerca de 30%. Possui diversas classificações de entidades médicas e classificações internacionais de doenças, todas elas tendo em comum um reduzido tempo de latência intravagin...

Linfohistiocitosis hemofagocítica secundaria a infección crónica activa por virus de Epstein-Barr en un hospital pediátrico en México: series de casos y revisión de la literatura
Hemophagocytic lymphohistiocytosis secondary to chronic active Epstein-Barr virus infection in a pediatric hospital in Mexico: case series and literature review

Rev. pediatr. electrón; 17 (4), 2020
INTRODUCCIÓN: La linfohistiocitosis hemofagocitica (HLH) secundario está asociada a enfermedades malignas, genéticas o autoinmunes, pero también a infecciones principalmente EBV hasta en un 70%, sin embargo hay poca información. Esta entidad se caracteriza por un curso variable y recurrente que conl...

Adaptación a la realidad de Latinoamérica de la Guía Clínica NASPGHAN/ESPGHAN 2016 sobre Diagnóstico, Prevención y Tratamiento de Infección por Helicobacter pylori en Pediatría

Rev. chil. pediatr; 91 (5), 2020
Resumen: Introducción: Las últimas guías clínicas conjuntas de NASPGHAN y ESPGHAN en relación a la infección por H. pylori publicadas el año 2016, contienen 20 afirmaciones que han sido cuestionadas en la práctica respecto a su aplicabilidad en Latinoamérica (LA); en particular en relación a ...

Case for diagnosis. Infiltrated areas on the trunk

An. bras. dermatol; 95 (5), 2020
Abstract Leprosy is an infectious disease with chronic evolution, caused by Mycobacterium leprae, an acid-fast bacillus that mainly affects the skin and peripheral nervous tissue. Many of the clinical manifestations of leprosy can mimic connective tissue diseases. The authors present the case of a 49-yea...

Prevenção de incapacidade física por hanseníase no Brasil: análise histórica

Resumo As orientações para prevenção de incapacidades físicas por hanseníase vêm ganhando destaque no controle da doença para além da poliquimioterapia. O objetivo deste artigo é descrever as mudanças, de forma cronológica, nas orientações técnicas para prevenção das incapacidades físic...

Comparison of palonosetron-dexamethasone and ondansetron-dexamethasone for prevention of postoperative nausea and vomiting in middle ear surgery: a randomized clinical trial

Rev. bras. anestesiol; 70 (5), 2020
Abstract Background: Postoperative nausea and vomiting is the second most common complaint in the postoperative period after pain. The incidence of postoperative nausea and vomiting was 60-80% in middle ear surgeries in the absence of antiemetic prophylaxis. Because of this high incidence of postoperati...