Results: 496

Caracterización clínica y radiológica de pacientes positivos a la COVID-19
Clinical and radiological characterization of COVID-19 positive patients

Rev. cuba. med. mil; 50 (3), 2021
Introducción: Desde el surgimiento de los primeros casos en la pandemia de la COVID-19, se ha desarrollado una carrera vertiginosa en crear un espacio de investigación para el diagnóstico, tratamiento y control de la enfermedad. Objetivo: Describir las características clínicas y radiológicas de lo...

Optimized broad-range real-time PCR-based method for bacterial screening of platelet concentrates

Braz. j. biol; 81 (3), 2021
Abstract Bacterial contamination of blood components remains a major challenge in transfusion medicine, particularly, platelet concentrates (PCs) due to the storage conditions that support bacterial proliferation. In this study, we develop a rapid, sensitive and specific real-time PCR protocol for bacter...

Auditoria de higiene en instalaciones de la industria textil frente al Covid-19

Los trabajadores de la industria están expuestos a distintos tipos de riesgos, incluyendo la exposición laboral a agentes biológicos como virus, bacterias, hongos, parásitos, esporas o toxinas capaces de originar algún tipo de infección, enfermedad o toxicidad. Gran variedad de estos patógenos ha ...

Estrogen receptor mRNA determined by Quantitative Real-Time PCR in the nasal mucosa of women taking oral contraceptives

Int. j. morphol; 39 (4), 2021
SUMMARY: Estrogen receptors (ER) have been identified in human nasal mucosa, but its physiologic and pathologic impacts are not totally established. ER have been demonstrated in nasal mucosa by several authors, mainly by immunohistochemical method in nasal mucosa samples surgically removed. The present s...

Implementación de un sistema de detección de flavivirus en mosquitos

Los Flavivirus constituyen virus transmitidos por artrópodos, principalmente mosquitos. Pueden producir enfermedades en humanos y animales, también incluyen virus específicos de insectos que solo infectan y se replican en los insectos, no así en vertebrados. En Paraguay los virus dengue, fiebre amari...

CRISPR-mediated base editing in mice using cytosine deaminase base editor 4

BACKGROUND: Many human genetic diseases arise from point mutations. These genetic diseases can theoretically be corrected through gene therapy. However, gene therapy in clinical application is still far from mature. Nearly half of the pathogenic single-nucleotide polymorphisms (SNPs) are caused by G:C>A:...

C/EBPb converts bovine fibroblasts to adipocytes without hormone cocktail induction

BACKGROUND: Adipogenesis and fibrogenesis can be considered as a competitive process in muscle, which may affect the intramuscular fat deposition. The CCAAT/enhancer-binding protein beta (C/EBPb) plays an important role in adipogenesis, which is well-characterized in mice, but little known in bovine so f...

Utility of BMI-1 and NANOG expression levels in survival prediction of pediatric acute lymphoblastic leukemia

ABSTRACT Background Acute lymphoblastic leukemia (ALL) is the most common malignancy in children characterized by the overproduction and accumulation of immature lymphoid cells in the bone marrow and peripheral blood. The BMI-1 is an important component of the Polycomb Repressive Complex-1 (PRC1). It is...

MicroRNA-27b expression in rats submitted to physical exercise and experimental cerebral ischemia

Int. j. morphol; 39 (3), 2021
SUMMARY: Cerebral ischemia has not only a high mortality rate, which is the second leading cause of death worldwide, but is also responsible for severe disabilities in working age individuals, generating enormous public expending for treatment and rehabilitation of the affected individuals. The role of m...

Liver structural injury in leptin-deficient (ob/ob) mice: lipogenesis, fibrogenesis, inflammation, and apoptosis

Int. j. morphol; 39 (3), 2021
SUMMARY: Nonalcoholic fatty liver disease (NAFLD) might progress the steatosis to nonalcoholic steatohepatitis (NASH), reaching a cirrhosis state and possibly hepatocellular carcinoma. The liver of three-month-old C57BL/6J mice (wild-type, WT group, n=10) and leptin- deficient obese mice (ob/ob group, n=...