Results: 93

Effectual components of Polygonum ciliinerve protects against Staphylococcus aureus infection with immunomodulatory functions in C57BL/6 mice

Acta cir. bras; 33 (11), 2018
Abstract Purpose: To investigate the efficacy and mechanisms of root tuber of Polygonum ciliinerve (Nakai) ohwi (rPC) which has been used to treat bacterial infection in traditional Chinese medicine. Methods: With the mouse model of Staphylococcus aureus (S. aureus) pneumonia, the phenotype of rPC tre...

Effect of the bioprotectant agent trehalose on corneal epithelial healing after corneal cross-linking for keratoconus

Arq. bras. oftalmol; 81 (6), 2018
ABSTRACT Purpose: This study aimed to compare the effectiveness of eye drops containing a combination of sodium hyaluronate and trehalose and sodium hyaluronate for the treatment of corneal cross-linking and epithelial healing. Methods: This study included 46 eyes of 23 keratoconus patients who underwe...

Protective effects of baicalin on experimental myocardial infarction in rats

Abstract Objective: This study aimed to investigate the protective effects of baicalin on myocardial infarction in rats and explore the related mechanisms. Methods: Fifty Sprague Dawley rats were randomly divided into the control, model, and low-, medium- and high-dose baicalin groups. The latter 3 gro...

Investigation of Allium sativum's protective effect on ovarian reserve in an experimental ovarian injury model

Int. j. morphol; 36 (2), 2018
We aimed to evaluate the effects of detorsion and Allium sativum (garlic oil) treatment on the ovarian reserve in an ovarian torsion model. Ovarian torsion may lead to loss of ovarian tissue and infertility. It is an experimental rat study that was carried out on 16 sets of ovaries each, one for treatmen...

The protective effect of Papaverine and Alprostadil in rat testes after ischemia and reperfusion injury

Int. braz. j. urol; 44 (3), 2018
ABSTRACT Objective: To investigate the effect of papaverine and alprostadil on testicular torsion-detorsion injury in rats. Materials and Methods: A total of 40 male Wistar-Albino rats were used in this study. Four hours of right testicular torsion was applied to each group, excluding sham oper- ated g...

Antioxidant capacity of Momordica charantia extract and its protective effect on testicular damage in valproic acid-induced rats

Int. j. morphol; 36 (2), 2018
Although Momordica charantia (MC) has preventive effects on tissue injuries, antioxidant capacity and protective effect of MC pulp and peel (MCP) on valproic acid (VPA)-testicular damage have never been reported. Fresh MCPs were aqueous extracted and determined for antioxidant capacity and momordicine I ...

Perfil fitoquímico e atividade gastroprotetora dos frutos de Eugenia mattosii

Arq. gastroenterol; 55 (2), 2018
ABSTRACT BACKGROUND: Extracts obtained from plants and fruits provide a relatively safe and practical alternative for the conventional medicine of gastrointestinal diseases. The specie Eugenia mattosii, popularly known in Brazil as "cerejinha", belongs to Myrtaceae family. Species of this family present...

Evaluation of prophylactic and therapeutic effects of sildenafil on acute radiation proctitis in rats

Acta cir. bras; 33 (4), 2018
Abstract Purpose: To investigate the prophylactic and therapeutical effects of sildenafil in a model of acute radiation proctitis (ARP). Methods: All experimental procedures of this study was examined by histopathological, immunohistochemical and transmission electron microscopic analysis. Results: ...

The role of oxymatrine in regulating TGF-β1 in rats with hepatic fibrosis

Acta cir. bras; 33 (3), 2018
Abstract Purpose: To investigate whether oxymatrine (OMT) prevents hepatic fibrosis in rats by regulating liver transforming growth factor β1 (TGF-β1) level. Methods: Hepatic fibrosis was induced in rats by thioacetamide (TAA). Blood was collected at the end of week 12 to determine the leve...

Ghrelin and gastrointestinal wound healing. A new perspective for colorectal surgery

Acta cir. bras; 33 (3), 2018