Abstract Solid dispersions (SDs) of ursolic acid (UA) were developed using polyvinylpyrrolidone K30 (PVP K30) in combination with non-ionic surfactants, such as D-α-tocopherol polyethylene glycol 1000 succinate (TPGS) or poloxamer 407 (P407) with the aim of enhancing solubility and in vitro release ...
A obesidade está associada ao desenvolvimento de doenças crônicas não transmissíveis como hipertensão, resistência insulínica, dislipidemia e esteatose hepática. O consumo de compostos bioativos impacta na manutenção da saúde e na prevenção de risco de desenvolvimento dessas doenças. Entre...
Envelhecer compreende um fenômeno complexo, natural e irreversível, que submete o organismo a inúmeras alterações nos processos biológicos, fisiológicos, ambientais, psicológicos, comportamentais e sociais. Esse processo é caracterizado por um declínio gradual dos mecanismos homeostáticos do o...
ABSTRACT Objective: To compare the agreement of images in white light (WL), fluorescence (FL), and digital radiographs (DR), on the diagnosis and treatment decisions for occlusal caries lesions against a micro-CT gold standard. Material and Methods: Ten extracted third molars, with enamel and/or dentin...
Suthovski, Gabriela;
Catarina, Alcione Santa;
Perin, Diana Paula;
Mainardes, Rubiana Mara;
Starikoff, Karina Ramirez;
Gallina, André Lazarin;
Azevedo, Maiara Garcia Blagitz;
Dalmolin, Fabíola;
Cervo, Luciana Velasques;
Benvegnú, Dalila Moter.
Abstract Bovine infectious mastitis is largely resistant to antibacterial treatment, mainly due to mechanisms of bacterial resistance in the biofilms formed by Staphylococcus aureus. Melaleuca (MEO) and citronella essential oils (CEO) are promising agents for reducing or eliminating biofilms. Free melale...
Vieira, Italo Rennan Sousa;
Silva, Ana Clara Lima Nunes;
Castro, Natalia Ruben;
Pinto, Cristal dos Santos Cerqueira;
Freitas, Zaida Maria Faria de;
Ricci-Júnior, Eduardo;
Santos, Elisabete Pereira dos;
Camara, Adriana Leandro;
Costa, Maria Célia Pires;
Adam Conte-Junior, Carlos.
Abstract Oil-in-water photoprotective nanoemulsions (NEs) were developed using Babassu (BBS) lipophilic extract, nonionic surfactants, and low concentrations of organic sunscreens by ultrasonic processing. BBS extract was chosen due to its suitable physicochemical properties (acidity index, peroxide inde...
Abstract Acai (Euterpe oleracea Mart.) and guarana (Paullinia cupana Kunth) are native species from the Amazon Forest that in folk medicine are used to treat several diseases due to their anti-inflammatory and antioxidant properties. This review brings together findings from different studies on the pote...
Abstract We report here microemulsions (MEs) for topical delivery of protoporphyrin IX (PpIX) for Photodynamic Therapy (PDT) of skin cancers. Selected MEs consisting of Oil/Water (O/W) bicontinuous (BC) and Water/Oil (W/O) preparations were characterized as to pH, nanometric size, zeta potential, drug co...
ABSTRACT Diabetes is a life-threatening disease, and currently available synthetic medicines for treating diabetes are associated with various side effects. Therefore, there is an unmet need to develop herbal remedies against diabetes as an alternative to synthetic medicines. Although local healers use t...
Abstract Piper nigrum (black pepper) is used in Indian traditional medicine and its main alkaloid, Piperine (PIP), presents antioxidant, antitumor and neuroprotective pharmacological properties. This substance is insoluble in aqueous media and can irritate the gastrointestinal tract. Aiming to avoid thes...
Piper nigrum/efectos adversos,
Composición de Medicamentos/instrumentación,
d0002840,
Alcaloides/efectos adversos,
Antioxidantes/efectos adversos,
Análisis Espectral/métodos,
Comprimidos/clasificación,
Medicina Tradicional/instrumentación,
Microscopía Electrónica de Rastreo/métodos,
Tracto Gastrointestinal/anomalías,
Técnicas In Vitro/métodos
