Background: Soil salinity can significantly reduce crop production, but the molecular mechanism of salinity tolerance in peanut is poorly understood. A mutant (S1) with higher salinity resistance than its mutagenic parent HY22 (S3) was obtained. Transcriptome sequencing and digital gene expression (DGE) ...
Pacientes com câncer de reto (CaRe) em estadio II ou III são tratados com radioquimioterapia neoadjuvante (nCRT), a qual é responsável pela diminuição de recidivas loco-regionais e amputação do esfíncter. A resposta à terapia é variável, incluindo aqueles que não respondem ao tratamento e os...
BACKGROUND Trypanosoma cruzi is an important protozoan parasite and the causative agent of Chagas disease. A critical step in understanding T. cruzi biology is the study of cellular and molecular features exhibited during its growth curve. OBJECTIVES We aimed to acquire a global view of the gene expres...
Dorsal root ganglia (DRG) neurons regenerate spontaneously after traumatic or surgical injury. Long noncoding RNAs (lncRNAs) are involved in various biological regulation processes. Conditions of lncRNAs in DRG neuron injury deserve to be further investigated. Transcriptomic analysis was performed by hig...
Secuencia de Bases,
Western Blotting,
Mapeo Cromosómico,
Modelos Animales de Enfermedad,
Ganglios Espinales/lesiones,
Ganglios Espinales/metabolismo,
Ganglios Espinales/fisiopatología,
Regulación de la Expresión Génica,
Datos de Secuencia Molecular,
Neuralgia/metabolismo,
Traumatismos de los Nervios Periféricos/metabolismo,
ARN Largo no Codificante/metabolismo,
ARN Mensajero/genética,
Nervio Ciático/metabolismo,
Transcriptoma
In this study, we screened differentially expressed genes in a multidrug-resistant isolate strain of Clostridium perfringens by RNA sequencing. We also separated and identified differentially expressed proteins (DEPs) in the isolate strain by two-dimensional electrophoresis (2-DE) and mass spectrometry (...
Proteínas Bacterianas/genética,
Proteínas Bacterianas/metabolismo,
Clostridium perfringens/clasificación,
Clostridium perfringens/efectos de los fármacos,
Clostridium perfringens/genética,
Clostridium perfringens/metabolismo,
ADN Complementario,
Farmacorresistencia Bacteriana Múltiple/genética,
Electroforesis en Gel Bidimensional/métodos,
Regulación Bacteriana de la Expresión Génica/genética,
Ontología de Genes,
Genes MDR,
Genoma Bacteriano/genética,
Espectrometría de Masas/métodos,
Proteoma/genética,
Análisis de Secuencia de ARN/métodos,
Transcriptoma/genética
PURPOSE: This aim of this study was to investigate the key genes and pathways involved in the response to pain in goat and sheep by transcriptome sequencing. METHODS: Chronic pain was induced with the injection of the complete Freund's adjuvant (CFA) in sheep and goats. The animals were divided into four...
Dolor Crónico/genética,
Ganglios Espinales/fisiopatología,
Transducción de Señal/genética,
Transcriptoma/genética,
Dolor Crónico/inducido químicamente,
Dolor Crónico/fisiopatología,
Umbral del Dolor/fisiología,
Transducción de Señal/fisiología,
Transcriptoma/fisiología,
Adyuvantes Inmunológicos,
Modelos Animales de Enfermedad,
Adyuvante de Freund,
Perfilación de la Expresión Génica,
Biblioteca de Genes,
Ontología de Genes,
Cabras,
Ovinos
BACKGROUND: Diffuse intrinsic pontine glioma (DIPG) is the main cause of pediatric brain tumor death. This study was designed to identify key genes associated with DIPG. METHODS: The gene expression profile GSE50021, which consisted of 35 pediatric DIPG samples and 10 normal brain samples, was downloaded...
The mosquito Aedes aegypti is the main vector of several arthropod-borne diseases that have global impacts. In a previous meta-analysis, our group identified a vector gene set containing 110 genes strongly associated with infections of dengue, West Nile and yellow fever viruses. Of these 110 genes, four ...
Background: Idesia polycarpa Maxim. var. vestita Diels, a dioecious plant, is widely used for biodiesel due to the high oil content of its fruits. However, it is hard to distinguish its sex in the seedling stage, which makes breeding and production problematic as only the female tree can produce fruits, ...
Background: Platycladus orientalis has an extremely long life span of several thousands of years, attracting great interests in the mechanisms involved in such successful senescence regulation and resistance at physiological and molecular levels. Results: The levels of reactive oxygen species (ROS) were ...
