Results: 64

Detection of blaNDM-1 in Stenotrophomonas maltophilia isolated from Brazilian soil

Mem. Inst. Oswaldo Cruz; 113 (6), 2018
This study reports the presence of the blaNDM-1 gene in an isolate of Stenotrophomonas maltophilia obtained from a Brazilian soil, inside an IncA/C plasmid with ~ 45 Kb. To the best of our knowledge, this is the second report in the world and the first in Brazil of NDM-producing bacterium isolated from s...

Genomic analysis of bifunctional Class C-Class D β-lactamases in environmental bacteria

Mem. Inst. Oswaldo Cruz; 113 (8), 2018
β-lactamases, which are found in several bacterial species and environments, are the main cause of resistance to β-lactams in Gram-negative bacteria. In 2009, a protein (LRA-13) with two β-lactamase domains (one class C domain and one class D domain) was experimentally characterised, and a...

Detection of virulence and β-lactamase encoding genes in Enterobacter aerogenes and Enterobacter cloacae clinical isolates from Brazil

Braz. j. microbiol; 49 (supl.1), 2018
ABSTRACT Enterobacter cloacae and E. aerogenes have been increasingly reported as important opportunistic pathogens. In this study, a high prevalence of multi-drug resistant isolates from Brazil, harboring several β-lactamase encoding genes was found. Several virulence genes were observed in E. aero...

Caracterización molecular y patrón de susceptibilidad antimicrobiana de Escherichia coli productora de β -lactamasas de espectro extendido en infección del tracto urinario adquirida en la comunidad

Rev. chil. infectol; 35 (1), 2018
Resumen Introducción Las infecciones del tracto urinario adquiridas en la comunidad (ITUac) causadas por cepas de Escherichia coli productoras de β-lactamasas de espectro extendido (BLEE), principalmente por cepas que contienen el gen blaCTX-M-15, es un fenómeno creciente a nivel mundial. Objeti...

Detection of multidrug-resistant Pseudomonas aeruginosa harboring bla GES-1 and bla GES-11 in Recife, Brazil

Abstract INTRODUCTION: Pseudomonas aeruginosa, an important pathogen globally, presents several resistance mechanisms. This study aimed to investigate the presence of bla GES in clinical isolates of Pseudomonas aeruginosa obtained from various clinical specimens from patients admitted to three different...

Characterization of multidrug-resistant Acinetobacter ssp. strains isolated from medical intensive care units in Cali - Colombia

Colomb. med; 48 (4), 2017
Abstract Introduction: The extensive use of antibiotics has led to the emergence of multi-resistant strains in some species of the genus Acinetobacter. Objective: To investigate the molecular characteristics of multidrug-resistant of Acinetobacter ssp. strains isolated from 52 patients collected betwee...

Glimpse into the genome sequence of a multidrug-resistant Acinetobacter pittii ST950 clinical isolate carrying the blaOXA-72 and blaOXA-533 genes in China

Mem. Inst. Oswaldo Cruz; 112 (10), 2017
The development of carbapenem-resistant Acinetobacter species is of serious concern in the hospital settings and naturally occurring oxacillinase genes (blaOXA) have been identified in several Acinetobacter species. In this study, we report the genome sequence of A. pittii TCM178 belongs to ST950, a mult...

KPC: Klebsiella pneumoniae carbapenemasa, principal carbapenemasa en enterobacterias

Rev. chil. infectol; 34 (5), 2017
Resumen En la actualidad, la diseminación de enterobacterias productoras de carbapenemasas se considera un grave problema en clínica debido al fracaso en el tratamiento de las infecciones que ellas producen. Entre las carbapenemasas, la enzima KPC se ha diseminado mundialmente y ha sido identificada en...

Carbapenem-resistant Pseudomonas aeruginosa: association with virulence genes and biofilm formation

Braz. j. microbiol; 48 (2), 2017
Abstract Pseudomonas aeruginosa is an opportunistic pathogen that causes frequently nosocomial infections, currently becoming more difficult to treat due to the various resistance mechanisms and different virulence factors. The purpose of this study was to determine the risk factors independently associa...

Draft genome sequence of a GES-5-producing Serratia marcescens isolated in southern Brazil

Braz. j. microbiol; 48 (2), 2017
Abstract Serratia marcescens is a Gram-negative rod intrinsically resistant to polymyxins and usually associated with wound, respiratory and urinary tract infections. The whole genome of the first GES-5-producing S. marcescens isolated from a Brazilian patient was sequenced using Ion Torrent PGM System. ...