Abstract Several studies show that the prevalence of multidrug-resistant HIV-1 virus is declining over time. A retrospective cohort study was carried out to evaluate the trends of drug resistance in antiretroviral treatment-exposed individuals in a state of a middle-income country, Minas Gerais, southeas...
Fármacos Anti-VIH/farmacología,
Fármacos Anti-VIH/uso terapéutico,
Brasil,
Estudios de Cohortes,
Farmacorresistencia Viral Múltiple/genética,
Genotipo,
Infecciones por VIH/tratamiento farmacológico,
Infecciones por VIH/virología,
VIH-1/efectos de los fármacos,
VIH-1/genética,
Mutación,
Prevalencia,
Estudios Retrospectivos
Abstract Staphylococcus aureus and Staphylococcus saprophyticus are the most common and most important staphylococcal species associated with urinary tract infections. The objective of the present study was to compare and to evaluate the accuracy of four phenotypic methods for the detection of beta-lacta...
Pruebas de Sensibilidad Microbiana,
Resistencia betalactámica,
beta-Lactamasas/genética,
beta-Lactamasas/metabolismo,
Pruebas Antimicrobianas de Difusión por Disco,
Genotipo,
Resistencia a las Penicilinas,
Sensibilidad y Especificidad,
Infecciones Estafilocócicas/microbiología,
Staphylococcus saprophyticus/efectos de los fármacos,
Staphylococcus saprophyticus/genética,
Staphylococcus saprophyticus/metabolismo,
Infecciones Urinarias/microbiología
ABSTRACT BACKGROUND Gastroesophageal reflux disease (GERD) is characterized by diverse symptoms. There is an evidence for a genetic component to GERD as supported by familial aggregation of this disease. OBJECTIVE To investigate whether certain human leucocyte antigen genes HLA-DRB1 are associated with...
Chaves, Amanda Caroline Silva;
Fraga, Vanessa Gomes;
Guimarães, Henrique Cerqueira;
Teixeira, Antonio Lucio;
Barbosa, Maira Tonidandel;
Carvalho, Maria das Graças;
Mota, Ana Paula Lucas;
Silva, Ieda de Fátima Oliveira;
Caramelli, Paulo;
Gomes, Karina Braga;
Alpoim, Patrícia Nessralla.
ABSTRACT This prospective study aimed to evaluate the influence of the -351A/G XbaI polymorphism in the estrogen receptor-alpha (ESR-1) gene on global cognitive scores of a community sample of healthy oldest-old individuals within one year of follow up. Methods The individuals were categorized in two g...
Abstract INTRODUCTION: This study quantified Mycobacterium leprae bacilli in environmental water samples from five municipalities in the State of Ceará by quantitative polymerase chain reaction (qPCR) and compared the identified genotypes with those obtained from leprosy patient biopsies. METHODS: We ...
Abstract Toll-like receptors (TLRs) are critical mediators of the inflammatory response to malarial infection, and gene polymorphisms affecting TLR function may be partially responsible for inter-individual variation in disease manifestation. However, there are inconsistencies in the associations of comm...
Araujo, Zaida;
Palacios, Andrea;
Biomon, Rubén;
Rivas-Santiago, Bruno;
Serrano, Carmen Judith;
Enciso-Moreno, Leonor;
López-Ramos, Juan Ernesto;
Wide, Albina;
Jiménez, Juan Carlos;
Larrea, Carlos Fernández de;
Enciso-Moreno, José Antonio.
Abstract INTRODUCTION: Interferon-γ (IFN-γ) plays a crucial role in resistance to mycobacterial diseases; accordingly, variants of the gene encoding this cytokine may be associated with elevated risk of contracting pulmonary tuberculosis (TB). METHODS: Blood samples were collected from 135 W...
Estudios Transversales,
Enfermedades Endémicas,
Genotipo,
Indígenas Sudamericanos/estadística & datos numéricos,
Interferón gamma/genética,
Interferón gamma/metabolismo,
Persona de Mediana Edad,
Reacción en Cadena de la Polimerasa,
Polimorfismo Genético/genética,
Prueba de Tuberculina,
Tuberculosis Pulmonar/diagnóstico,
Tuberculosis Pulmonar/epidemiología,
Tuberculosis Pulmonar/etnología,
Venezuela/epidemiología
Summary Introduction: Virus surveillance strategies and genetic characterization of human parvovirus B19 (B19V) are important tools for regional and global control of viral outbreak. In São Paulo, Brazil, we performed a study of B19V by monitoring the spread of this virus, which is an infectious agent ...
Anemia/virología,
Anticuerpos Antivirales/sangre,
Brasil,
ADN Viral/sangre,
Eritema Infeccioso/sangre,
Eritema Infeccioso/virología,
Genotipo,
Hidropesía Fetal/virología,
Inmunoensayo,
Inmunoglobulina G/sangre,
Inmunoglobulina M/sangre,
Persona de Mediana Edad,
Parvovirus B19 Humano/genética,
Parvovirus B19 Humano/aislamiento & purificación,
Vigilancia de la Población,
Reacción en Cadena de la Polimerasa de Transcriptasa Inversa
Since the description of Candida orthopsilosis and C. metapsilosis in 2005, several methods have been proposed to identify and differentiate these species from C. parapsilosis sensu stricto. Species-specific uniplex polymerase chain reaction (PCR) was performed and compared with sequencing of the D1/D2 r...
Candida/clasificación,
Candida/genética,
Candida/aislamiento & purificación,
Dermatoglifia del ADN,
ADN de Hongos/análisis,
ADN Espaciador Ribosómico/genética,
Genotipo,
Técnicas de Tipificación Micológica/métodos,
Reacción en Cadena de la Polimerasa,
Polimorfismo de Longitud del Fragmento de Restricción,
Análisis de Secuencia de ADN
Abstract Staphylococcus aureus is an important cause of bloodstream infections. Therefore, the main purpose of this work was to characterize a collection of 139 S. aureus isolates from bloodstream infections in two public hospitals in relation to their antimicrobial susceptibility profile, staphylococcal...
Antibacterianos/farmacología,
Técnicas de Tipificación Bacteriana,
Brasil,
ADN Bacteriano/genética,
Pruebas Antimicrobianas de Difusión por Disco,
Electroforesis en Gel de Campo Pulsado,
Genotipo,
Hospitales Públicos,
Staphylococcus aureus Resistente a Meticilina/efectos de los fármacos,
Staphylococcus aureus Resistente a Meticilina/genética,
Tipificación de Secuencias Multilocus,
Mupirocina/farmacología,
Infecciones Estafilocócicas/microbiología
