Ju, J;
Chen, W;
Lai, Y;
Wang, L;
Wang, H;
Chen, WJ;
Zhao, X;
Ye, H;
LI, Y;
Zhang, Y.
Oxidative stress plays an important role in the development of diabetic cardiomyopathy. In the present study, we determined whether the effect of astragalus polysaccharides (APS) on diabetic cardiomyopathy was associated with its impact on oxidative stress. Streptozotocin (STZ)-induced diabetic mice and ...
Apoptosis/efectos de los fármacos,
Planta del Astrágalo/química,
Proliferación Celular/efectos de los fármacos,
Diabetes Mellitus Experimental/tratamiento farmacológico,
Diabetes Mellitus Experimental/patología,
Cardiomiopatías Diabéticas/tratamiento farmacológico,
Cardiomiopatías Diabéticas/patología,
Ratones Endogámicos C57BL,
Ratones Noqueados,
Microscopía Electrónica de Transmisión,
Miocitos Cardíacos/efectos de los fármacos,
Miocitos Cardíacos/ultraestructura,
Estrés Oxidativo/efectos de los fármacos,
Extractos Vegetales/uso terapéutico,
Polisacáridos/uso terapéutico,
Estreptozocina,
Superóxido Dismutasa/genética
Although acute exercise is apparently pro-inflammatory and increases oxidative stress, it can promote the necessary stress stimulus to train chronic adaptations in patients with chronic heart failure (CHF). This study aimed to compare the effects of exercise intensity and duration on the inflammatory mar...
Biomarcadores/sangre,
Catalasa/sangre,
Enfermedad Crónica,
Prueba de Esfuerzo,
Insuficiencia Cardíaca/sangre,
Insuficiencia Cardíaca/inmunología,
Insuficiencia Cardíaca/fisiopatología,
Inflamación/sangre,
Inflamación/inmunología,
Inflamación/fisiopatología,
Interleucina-6/sangre,
Malondialdehído/sangre,
Estrés Oxidativo/fisiología,
Receptores del Factor de Necrosis Tumoral/sangre,
Superóxido Dismutasa/sangre
To study what kind of role uric acid play on the relationship between oxidative Stress and inflammation in peripheral and cerebral system of oxonate-induced hyperuricemic rats. Twenty-six eight male Wistar rats were divided into two groups randomly. Potassium oxonate was used to establish hyperuricemic m...
Abstract Introduction: Parkinson's disease (PD) is characterized by nigrostriatal degeneration, with dopaminergic depletion, and inflammatory and oxidative changes in the brain, leading to movement and coordination disorders. Recent studies have shown that treadmill training can be beneficial for these ...
Abstract: This study aimed to assess the impact of hyperlipidemia on healthy and diseased periodontal tissue by evaluating oxidative stress biomarkers in gingival crevicular fluid (GCF). Clinical periodontal parameters and blood serum lipid, GCF malondialdehyde (MDA), protein carbonyl (PC), and total ant...
Análisis de Varianza,
Estudios de Casos y Controles,
Colesterol/sangre,
Periodontitis Crónica/sangre,
Periodontitis Crónica/etiología,
Ensayo de Inmunoadsorción Enzimática,
Líquido del Surco Gingival/metabolismo,
Gingivitis/sangre,
Gingivitis/etiología,
Hiperlipidemias/sangre,
Hiperlipidemias/complicaciones,
Malondialdehído/sangre,
Persona de Mediana Edad,
Estrés Oxidativo/fisiología,
Carbonilación Proteica/fisiología,
Valores de Referencia,
Estadísticas no Paramétricas,
Triglicéridos/sangre
Background Globally, snake envenomation is a well-known cause of death and morbidity. In many cases of snakebite, myonecrosis, dermonecrosis, hemorrhage and neurotoxicity are present. Some of these symptoms may be provoked by the envenomation itself, but others are secondary effects of the produced oxid...
ABSTRACT The present study aimed to evaluate the effects of benzocaine and tricaine methanesulfonate on oxidative stress parameters of juvenile tambaqui tissues. Fish (n=80) were anesthetized with benzocaine (100 mg L-1) or tricaine (240 mg L-1) and two control groups were used (non-anesthetized fish and...
In this study, we aim to examine effects of an experimentally induced unilateral varicose ovarian vein on the activities of anti-oxidant enzymes in an adult rat ovary. In this experimental study, a total of 30 adult female Wistar albino rats were divided into three groups. 10 rats in group 1 as the varic...
ABSTRACT Purpose: We evaluated the efficacy of lycopene, a dietary carotenoid and potent antioxidant, against ocular inflammation and oxidative stress in an experimental uveitis model. Methods: Endotoxin-induced uveitis (EIU) was induced in Sprague-Dawley rats by a single subcutaneous injection of 200 ...
Antiinflamatorios/uso terapéutico,
Antioxidantes/uso terapéutico,
Humor Acuoso/metabolismo,
Carotenoides/uso terapéutico,
Modelos Animales de Enfermedad,
Ojo/patología,
Interleucina-6/metabolismo,
Lipopolisacáridos,
Licopeno,
Óxido Nítrico/metabolismo,
Estrés Oxidativo,
Ratas Sprague-Dawley,
Factor de Necrosis Tumoral alfa/metabolismo,
Uveítis/inducido químicamente,
Uveítis/tratamiento farmacológico,
Uveítis/patología
LOX-1 es un receptor endotelial de la familia de las lectinas. Su actividad biológica tiene un fuerte impacto en los fenómenos inflamatorios, oxidativos y aterogénicos endoteliales. Cuando se conoció el receptor de la lipoproteína de baja densidad (RLDL) y su regulación, se afirmó el papel aterog...
