ABSTRACT Vortioxetine is a multimodal antidepressant agent that modulates 5-HT receptors and inhibits the serotonin transporter. It is indicated especially in cases of major depressive disorder related to cognitive dysfunction. There are many studies investigating the effects of antidepressants on the se...
Electrocorticografía,
Epilepsia/inducido químicamente,
Epilepsia/tratamiento farmacológico,
Epilepsia/fisiopatología,
Penicilinas,
Distribución Aleatoria,
Ratas Wistar,
Reproducibilidad de los Resultados,
Agonistas del Receptor de Serotonina 5-HT1/farmacología,
Factores de Tiempo,
Resultado del Tratamiento,
Vortioxetina/farmacología
The renal glomerulus is coated by fenestrated endothelial cells and externally covered by specialized epithelial cells, known as podocytes. Scanning electron microscopy becomes an important and effective tool for its studies. Normally, samples destined for scanning microscopy are covered with a thin meta...
Cisplatin is an antineoplastic agent with neuropathy as one of its major side effect. However, effective treatment is lacking. Increasing evidence suggests that cisplatin might damage nerve capillaries leading to impaired functions of blood-nerve barrier (BNB) and neuropathy. This study was aimed to exam...
ABSTRACT Objective Determine the milk quality effect during lactation on the metabolic and thyroid programming of hypothyroid offspring. Materials and methods Ten-week-old female Wistar rats were divided into two groups: euthyroid and thyroidectomy-caused hypothyroidism. The rats were matted and, one...
ABSTRACT Objective Hyperthyroidism causes many injuries in its target organs and the consequences are reflected systemically. As systemic alterations in hyperthyroidism at earlier stages have received partial attention, this study aimed to investigate systemic redox and inflammatory status at an early ...
Antioxidantes/metabolismo,
Modelos Animales de Enfermedad,
Eritrocitos/efectos de los fármacos,
Eritrocitos/metabolismo,
Hipertiroidismo/sangre,
Hipertiroidismo/metabolismo,
Oxidación-Reducción,
Estrés Oxidativo/efectos de los fármacos,
Pentosas,
Ratas Wistar,
Tiroxina
RESUMEN: Evaluar el proceso de reparación alveolar en ratas sometidas a cirugía de simulacro u ovariectomizadas tras el relleno alveolar con coágulo o con biosilicato cristalino. Sesenta ratas Wistar fueron divididas en cuatro grupos (n=15) de acuerdo con el tratamiento: Grupo 1- ratas sometidas a cir...
Sustitutos de Huesos,
Huesos/citología,
Cerámica,
Experimentación Animal,
Ratas Wistar,
Brasil,
Ovariectomía,
Aumento de la Cresta Alveolar,
Regeneración Ósea,
Silicatos,
28599
O consumo de bebidas alcoólicas na gravidez consiste em um importante problema de saúde pública, visto que, pode causar prejuízos na organogênese de diversos órgãos, incluindo o estômago, entretanto, poucos estudos avaliam o efeito da exposição pré-natal ao álcool nesse órgão. O objetivo d...
Estómago,
Etanol,
Consumo de Bebidas Alcohólicas,
Células Epiteliales,
Epitelio,
Técnicas Histológicas,
Membrana Mucosa,
Organogénesis,
Músculo Liso/embriología,
Preñez,
Nivel de Alcohol en Sangre,
Ratas Wistar/microbiología,
Agua Destilada,
Acetaldehído/análisis
Introducción: el etanol es un agente teratógeno cuyo consumo excesivo representa un importante problema de salud a nivel mundial. Objetivo: demostrar el papel protector del ácido fólico sobre el Sistema Nervioso Central y las dimensiones craneofaciales, en un biomodelo de intoxicación alcohólica p...
Abstract Background: Mercury's deleterious effects are associated with increased cardiovascular risk. Objective: To determine whether chronic exposure to inorganic mercury increases the activity of angiotensin-converting enzyme and its relationship with oxidative stress in several organs and tissues. ...
Aorta/enzimología,
Presión Sanguínea/efectos de los fármacos,
Encéfalo/enzimología,
Corazón,
Hipertensión/metabolismo,
Hipertensión/fisiopatología,
Riñón/enzimología,
Pulmón/enzimología,
Malondialdehído/sangre,
Mercurio/toxicidad,
Intoxicación por Mercurio/complicaciones,
Estrés Oxidativo/efectos de los fármacos,
Peptidil-Dipeptidasa A/análisis,
Peptidil-Dipeptidasa A/efectos de los fármacos,
Ratas Endogámicas SHR,
Ratas Wistar,
Valores de Referencia,
Factores de Riesgo,
Factores de Tiempo
Abstract Increased oxygen consumption and activation of specific metabolic pathways during or after physical exercise lead to the formation of reactive oxygen and nitrogen species. An investigation was made into the effects of pequi oil supplementation in protecting liver cells against injury resulting ...
