Almeida, Carolina Medeiros de;
Lima, Rennaly de Freitas;
Costa, Tereza Karla Vieira Lopes da;
Sousa, Ilza Maria de Oliveira;
Cabral, Elaine Cristina;
Basting, Rosanna Tarkany;
Torre, Adriana Della;
Cavalcanti, Yuri Wanderley;
Rosalen, Pedro Luiz;
Duarte, Marta Cristina Teixeira;
Ruiz, Ana Lúcia Tasca Gois;
Foglio, Mary Ann;
Godoy, Gustavo Pina;
Costa, Edja Maria Melo de Brito.
Abstract: The aim of this study was to evaluate in vitro the antifungal, antibiofilm and antiproliferative activities of the extract from the leaves of Guapira graciliflora Mart. The phytochemical characterization of the extract was performed using electrospray ionization mass spectrometry (ESI-MS). The ...
Antifúngicos/aislamiento & purificación,
Antifúngicos/farmacología,
Biopelículas/efectos de los fármacos,
Biopelículas/crecimiento & desarrollo,
Candida/efectos de los fármacos,
Proliferación Celular/efectos de los fármacos,
Supervivencia Celular/efectos de los fármacos,
Dosificación Letal Mediana,
Pruebas de Sensibilidad Microbiana,
Nyctaginaceae/química,
Extractos Vegetales/farmacología
Cuscuta chinensis polysaccharide (CPS) was extracted using hot water and enzymatically hydrolyzed C. chinensis polysaccharide (ECPS) was produced by the mannase enzymatic hydrolysis process. The purpose of this research was to investigate the antimelanogenic activity of ECPS and CPS in B16F10 melanoma ce...
Antineoplásicos Fitogénicos/farmacología,
Antioxidantes/química,
Antioxidantes/aislamiento & purificación,
Antioxidantes/farmacología,
Línea Celular Tumoral,
Cuscuta/química,
Hidrólisis,
Melanocitos/efectos de los fármacos,
Melanoma Experimental/patología,
Extractos Vegetales/química,
Extractos Vegetales/farmacología,
Polisacáridos/química,
Polisacáridos/aislamiento & purificación,
Polisacáridos/farmacología,
Semillas/química
Guarana (Paullinia cupana) is habitually ingested by people in the Amazon region and is a key ingredient in various energy drinks consumed worldwide. Extension in longevity and low prevalence of chronic age-related diseases have been associated to habitual intake of guarana. Anti-aging potential of guara...
DNA repair pathways, cell cycle checkpoints, and redox protection systems are essential factors for securing genomic stability. The aim of the present study was to analyze the effect of Ilex paraguariensis (Ip) infusion and one of its polyphenolic components rutin on cellular and molecular damage induced...
Antimutagênicos/farmacología,
Supervivencia Celular/efectos de los fármacos,
Supervivencia Celular/efectos de la radiación,
Células Cultivadas,
Cromatografía Liquida,
Roturas del ADN de Doble Cadena,
Reparación del ADN,
ADN de Hongos/efectos de la radiación,
Relación Dosis-Respuesta en la Radiación,
Rayos gamma,
Ilex paraguariensis/química,
Espectrometría de Masas,
Mutagénesis,
Tasa de Mutación,
Extractos Vegetales/farmacología,
Protección Radiológica/métodos,
Reproducibilidad de los Resultados,
Rutina/farmacología,
Saccharomyces cerevisiae/efectos de los fármacos,
Saccharomyces cerevisiae/efectos de la radiación
Abstract Stroke is the third leading cause of mortality and disability in industrial countries. Treatment with herbs with antioxidant properties has been reported to be an alternative to the conventional treatments. This study was conducted to investigate the effect of Anchusa italica extract on hippocam...
ABSTRACT Antioxidants from natural sources hold high values regarding their indispensible roles in the development of nutraceuticals, pharmaceuticals and cosmetic products. Oroxylum indicum L. is a common medicinal plant with a wide range of therapeutic properties, including a notable antioxidant potency...
ABSTRACT The aim of this study was to evaluate anti-hypoxia activity of polyphenolic extracts of Crataegus microphylla and Crataegus pentaegyn on mice. Three experimental models of hypoxia were considered, including asphyctic hypoxia, haemic hypoxia, and circulatory hypoxia. Polyphenolic extract of both ...
Abstract Considering the high prevalence of human cervical cancer and the adverse effects of the available treatments, it is important to develop studies involving plants. Eugenia uniflora L. is a Brazilian native plant widely used in folk medicine and some biological effects have already been described....
ABSTRACT The present study investigates the effect of cinnamon (Cinnamomum zeylanicumon) powder supplementation on glucose levels, lipid profiles, and oxidative stress parameters in alloxan-induced diabetic rats. Diabetes was induced in adult male Wistar rats via a single subcutaneous alloxan injection (...
Coelho, Angélica Gomes;
Lima Neto, José de Sousa;
Moura, Arkellau Kenned Silva;
Morais, Ilmara Cecilia Pinheiro da Silva;
Cunha, Francisco Valmor Macedo;
Melo-Neto, Bernardo;
Medeiros, Maria das Graças Freire de;
Vasconcelos, Eilika Andreia Feitosa;
Arcanjo, Daniel Dias Rufino;
Nunes, Lívio Cesar Cunha;
Citó, Antônia Maria das Graças Lopes.
ABSTRACT Lippia origanoides is a honey shrub which has showed hypotensive potential assessed by in vivo studies. The aim of this work is the development of a pharmaceutical formulation composed by an optimized extract obtained from aerial parts of L. origanoides. The quantification of the naringenin mark...
