Results: 723

Association of oxidative stress and DNA damage with grafting time in patients with multiple myeloma and lymphoma submitted to autologous hematopoietic stem cell transplantation

ABSTRACT The aim of the study was to investigate the association between oxidative stress and DNA damage with grafting time in patients submitted to autologous hematopoietic stem-cell transplantation (HSCT). The study included 37 patients submitted to autologous HSCT diagnosed with Multiple Myeloma (MM) ...

Efeitos da terapia fotodinâmica com aluminio – cloro ftalocianina sobre a peroxidação lipídica e produtos antioxidantes em tecidos inflamados animais
Effects of Photodynamic therapy aluminum - chloro phthalocyanine on lipid peroxidation products and antioxidant in animal tissues inflamed

A terapia fotodinâmica (TFD) envolve a administração de um agente fotossensibilizador (FS) seguida pela aplicação do laser, com comprimento de onda adequado, resultando em uma sequência de processos fotoquímicos e fotobiológicos, que geram espécies reativas de oxigênio (EROs). Este estudo avali...

Antioxidant effects of açaí seed ( Euterpe oleracea ) in anorexia-cachexia syndrome induced by Walker-256 tumor

Acta cir. bras; 31 (9), 2016
ABSTRACT PURPOSE: To assess antioxidant effects of açaí seed extract on anorexia-cachexia induced by Walker-256 tumor. METHODS: A population of 20 lab rats were distributed into four groups (n=5): Control Group (CG), which only received tumor inoculation. Experimental Group-100 (EG-100), with anima...

Antioxidant effect of mesalazine in the experimental colitis model induced by acetic acid

Abstract Introduction Inflammatory bowel disease (IBD) is characterized by a chronic inflammation of the gastrointestinal tract, without specific cause or pathogen. Objective The effect of mesalazine in a colitis model induced by acetic acid (AA) was evaluated. Methods We used 40 Wistar rats, ±350 g,...

Are PTH levels related to oxidative stress and inflammation in chronic kidney disease patients on hemodialysis?

J. bras. nefrol; 38 (3), 2016
Abstract Introduction: Patients at end stage renal disease have higher levels of inflammation and oxidative stress than the general population. Many factors contribute to these issues, and the parathyroid hormone (PTH) is also implicated. Objective: The study was conducted in order to assess the relati...

Relación entre la ingesta de antioxidantes, factores nutricionales e indicadores bioquímicos en voluntarios sanos
Relationship between antioxidant intake, nutritional factors and biochemical indicators in healthy volunteers

Arch. latinoam. nutr; 66 (3), 2016
El estrés oxidativo constituye un factor importante en el desarrollo de Enfermedades Cardiovasculares (ECVs) debido a los daños graves que provocan las especies reactivas de oxígeno en las biomoléculas, por lo que el consumo adecuado de vitaminas con propiedades antioxidantes podría prevenir o retra...

Conexiones entre tejido óseo y tejido graso: efecto de la obesidad sobre la salud ósea

La prevalencia de dos desórdenes crónicos como la osteoporosis y la obesidad se encuentra en aumento. La fisiopatología de ambas alteraciones metabólicas es multifactorial e incluye factores genéticos, factores ambientales y hormonales. Diversos estudios clínicos y experimentales demuestran la exis...

Parámetros hematológicos y de estrés oxidativo en pingüinos de Magallanes rehabilitados por contaminación con petróleo

Acta toxicol. argent; 24 (2), 2016
Los pingüinos de Magallanes son entre las aves marinas, la especie más afectada por la contaminación con petróleo en Chubut y Santa Cruz. Una de las consecuencias adversas de la exposición a hidrocarburos y otros contaminantes es el aumento de los niveles celulares de especies reactivas del oxígeno...

Effects of crocin on brain oxidative damage and aversive memory in a 6-OHDA model of Parkinson's disease

Arq. neuropsiquiatr; 74 (9), 2016
ABSTRACT The purpose of the present study was to investigate the effect of crocin on brain oxidative damage and memory deficits in a 6-hydroxydopamine (6-OHDA) model of Parkinson’s disease. Male Wistar rats were subjected to unilateral injection of 6-OHDA (16 µg) into the medial forebrain bundle a...

Aged Lewis rats exposed to low and moderate doses of rotenone are a good model for studying the process of protein aggregation and its effects upon central nervous system cell physiology

Arq. neuropsiquiatr; 74 (9), 2016
ABSTRACT Cell physiology is impaired before protein aggregation and this may be more relevant than inclusions themselves for neurodegeneration. The present study aimed to characterize an animal model to enable the analysis of the cell biology before and after protein aggregation. Ten-month-old Lewis rats...