Results: 657

Inflammatory bowel and oxidative stress changes in an experimental model of portal hypertension: action of N-acetylcysteine

Introduction: Portal hypertension (PH) is characterized by vasodilatation in the portal system and the bowel is one of the severely affected organs. N-acetylcysteine (NAC) is a molecule with important properties and widely used in clinical practice. Objective: To evaluate NAC action in the bowel of anim...

Effects of hydroalcoholic extract of Ziziphus jujuba on acetic acid induced ulcerative colitis in male rat (Rattus norvegicus)

Objective: To investigate the effects of hydroalcoholic extract of Ziziphus jujuba on the histopathological, tissue oxidative stress and inflammation plus to antioxidant pathways of colon tissue in rat with induced Ulcerative colitis. Materials and methods: Ulcerative colitis was induced in 80 rats thos...

Simple markers for subclinical inflammation in the different phases of bipolar affective disorder

Abstract Background: Recently, a growing number of publications have suggested that the immune-inflammatory system may be involved in the etiology of bipolar disorder (BD). Objective: The aim of this study was to investigate neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR), and red ce...

Effect of ozone and methylprednisolone treatment following crush type sciatic nerve injury

Acta cir. bras; 31 (11), 2016
ABSTRACT PURPOSE: To assess and compare the histopathological effects of ozone therapy and/or methylprednisolone (MPS) treatment on regeneration after crush type sciatic nerve injury. METHODS: Forty Sprague-Dawley male rats were randomly allocated into four groups. Four groups received the following r...

Evaluación de la actividad de Baccharis latifolia en modelos de artritis experimental

Con-ciencia (La Paz); 4 (2), 2016
La artritis reumatoide (AR) es una enfermedad crónica de naturaleza autoinmune e inflamatoria que conduce a la formación de pannus seguido de la destrucción de las articulaciones, se caracteriza por hiperplasia sinovial, inflamación y angiogénesis. La especie vegetal Baccharis latifolia es utilizada...

Polysaccharide extract of Mimosa tenuiflora stem barks stimulates acute inflammatory response via nitric oxide

Acta sci., Biol. sci; 38 (4), 2016
Mimosa tenuiflora (Mimosaceae) or “jurema-preta” is well distributed in the northeast Brazil, being popularly used to treat skin lesions, burns and inflammation. The healing effect of the alcoholic extract prepared with its barks corroborates the popular use. This study aimed to evaluate the inflamma...

Histological response to platelet-rich plasma added to polypropylene mesh implemented in rabbits

Int. braz. j. urol; 42 (5), 2016
ABSTRACT Introduction: The platelet-rich plasma (PRP) is part of a set of biotechnologies, providing some growth factors that promote repair of different tissues. The polypropylene meshes (PPM) are applied in the correction of abdominal defects, pelvic floor and urinary incontinence, however, they induc...

Pseudotumor esclerosante de órbita

Rev. bras. oftalmol; 75 (5), 2016
RESUMO O pseudotumor esclerosante de órbita é um subtipo raro de pseudotumor inflamatório idiopático de órbita. É mais comum em adultos e apresenta diagnóstico de exclusão. A primeira linha de tratamento são os esteroides. O subtipo esclerosante apresenta resposta moderada aos esteroides devido ...

Oral or topical administration of L-arginine changes the expression of TGF and iNOS and results in early wounds healing

Acta cir. bras; 31 (9), 2016
ABSTRACT PURPOSE: To evaluate the contribution of L-arginine oral or topical rout of administration in the surgical wound healing process. METHODS: L-arginine was orally or topically administrated to mice after a laparotomy model procedure. The wounds were analyzed to evaluate the granulation tissue by...

Antioxidant effect of mesalazine in the experimental colitis model induced by acetic acid

Abstract Introduction Inflammatory bowel disease (IBD) is characterized by a chronic inflammation of the gastrointestinal tract, without specific cause or pathogen. Objective The effect of mesalazine in a colitis model induced by acetic acid (AA) was evaluated. Methods We used 40 Wistar rats, ±350 g,...