Abstract COVID-19, the causative agent of which is a new type of coronavirus called SARS-CoV-2, has caused the most severe pandemic in the last 100 years. The condition is mainly respiratory, and up to 5 % of patients develop critical illness, a situation that has put enormous pressure on the health syst...
Betacoronavirus/aislamiento & purificación,
COVID-19,
Infecciones por Coronavirus/epidemiología,
Infecciones por Coronavirus/fisiopatología,
Infecciones por Coronavirus/terapia,
Cuidados Críticos/métodos,
Enfermedad Crítica,
Unidades de Cuidados Intensivos,
Pandemias,
Neumonía Viral/epidemiología,
Neumonía Viral/fisiopatología,
Neumonía Viral/terapia,
Respiración Artificial/estadística & datos numéricos,
SARS-CoV-2
Abstract Coronavirus disease 2019 (COVID-19), an infection caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is currently hitting the world in the form of a pandemic. Given that some reports suggest that this infection can also occur with neurologic manifestations, this narrative re...
Betacoronavirus/aislamiento & purificación,
COVID-19,
Prueba de COVID-19,
Técnicas de Laboratorio Clínico,
Infecciones por Coronavirus/complicaciones,
Infecciones por Coronavirus/diagnóstico,
Infecciones por Coronavirus/epidemiología,
Mareo/virología,
Cefalea/virología,
Enfermedades del Sistema Nervioso/diagnóstico,
Enfermedades del Sistema Nervioso/virología,
Trastornos del Olfato/virología,
Pandemias,
Neumonía Viral/complicaciones,
Neumonía Viral/diagnóstico,
Neumonía Viral/epidemiología,
SARS-CoV-2,
Trastornos del Gusto/virología
Abstract In the efforts to explain COVID-19 pathophysiology, studies are being carried out on the correspondence between the expression of SARS-CoV-2 cell receptors and viral sequences. ACE2, CD147 and TMPRSS2 receptors expression could indicate poorly explored potential infection targets. For the genomi...
Enzima Convertidora de Angiotensina 2,
Basigina/genética,
Betacoronavirus/aislamiento & purificación,
COVID-19,
Infecciones por Coronavirus/fisiopatología,
Infecciones por Coronavirus/virología,
Regulación de la Expresión Génica,
Pandemias,
Peptidil-Dipeptidasa A/genética,
Neumonía Viral/fisiopatología,
Neumonía Viral/virología,
SARS-CoV-2,
Serina Endopeptidasas/genética,
Testículo/virología,
Latencia del Virus
Abstract COVID-19 arrived to Latin America early in March 2020. Currently, strategies are being developed in Colombia focusing on the quarantine and social and economic capital reactivation, whereby the expected results are not being obtained. In this article, we propose to review scientific evidence-bas...
Abstract The disease caused by the new SARS-CoV-2 coronavirus (COVID-19) spread rapidly from China to the entire world. Approximately one third of SARS-CoV-2-infected patients have neurological disorders, especially those classified as severe cases and that require mechanical ventilation. On the other ha...
Betacoronavirus/aislamiento & purificación,
COVID-19,
Infecciones por Coronavirus/complicaciones,
Infecciones por Coronavirus/epidemiología,
Infecciones por Coronavirus/virología,
Progresión de la Enfermedad,
Unidades de Cuidados Intensivos/estadística & datos numéricos,
Enfermedades del Sistema Nervioso,
Enfermedades del Sistema Nervioso/fisiopatología,
Enfermedades del Sistema Nervioso/virología,
Pandemias,
Neumonía Viral/complicaciones,
Neumonía Viral/epidemiología,
Neumonía Viral,
Respiración Artificial/estadística & datos numéricos,
SARS-CoV-2,
Índice de Severidad de la Enfermedad,
Tropismo Viral
Abstract Introduction: Reports of dermatological manifestations in patients with COVID-19 suggest a possible cutaneous tropism of SARS-CoV-2; however, the capacity of this virus to infect the skin is unknown. Objective: To determine the susceptibility of the skin to SARS-CoV-2 infection based on the ex...
Enzima Convertidora de Angiotensina 2,
Betacoronavirus/aislamiento & purificación,
COVID-19,
Línea Celular,
Infecciones por Coronavirus/complicaciones,
Infecciones por Coronavirus/genética,
Regulación de la Expresión Génica,
Predisposición Genética a la Enfermedad,
Pandemias,
Peptidil-Dipeptidasa A/genética,
Neumonía Viral/complicaciones,
Neumonía Viral/genética,
SARS-CoV-2,
Serina Endopeptidasas/genética,
Enfermedades Cutáneas Virales/virología,
Tropismo Viral/fisiología,
Internalización del Virus,
Piel/virología
Abstract In December 2019, a striking appearance of new cases of viral pneumonia in Wuhan led to the detection of a novel coronavirus (SARS-CoV2). By analyzing patients with severe manifestations, it became apparent that 20 to 35% of patients who died had preexisting cardiovascular disease. This finding ...
SUMMARY There is a new global pandemic that emerged in China in 2019 that is threatening different populations with severe acute respiratory failure. The disease has enormous potential for transmissibility and requires drastic governmental measures, guided by social distancing and the use of protective d...
