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Marine organisms: an alternative source of potentially valuable natural products

Kelecom, Alphonse.
Mem. Inst. Oswaldo Cruz; 86 (supl.2), 1991
This paper recalls the outcoming of marine natural products research and reviews a selection of marirne bioactive metabolites in current use together with promising trends in marine pharmacology....
Antiinflamatorios, Antiinflamatorios no Esteroideos, Productos Biológicos/aislamiento & purificación, Hemodinámica/efectos de los fármacos, Biología Marina, Toxinas Marinas/química, Neoplasias/tratamiento farmacológico
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Inhibition of gastric secretion by a water extract from Baccharis triptera, Mart

Gamberini, Maria T; Skorupa, L. A; Souccar, Caden; Lapa, Antonio J.
Mem. Inst. Oswaldo Cruz; 86 (supl.2), 1991
Baccharus triptera Mart, is a widespread Compositae used in Brazilian folk medicine to treat gastrointestinal disturbances, rheumatic disease, mild fever, diabetes and as an anti-helminthic. Water extract of small branches of the plant (WE) administered to mice and rats (0.1 to 2 g/Kg, p.o) did not alter...
Analgésicos/farmacología, Antiinflamatorios/farmacología, Antidiarreicos/farmacología, Brasil, Evaluación de Medicamentos, Mucosa Gástrica/efectos de los fármacos, Mucosa Gástrica/metabolismo, Fármacos Gastrointestinales/farmacología, Parasimpatolíticos/farmacología, Extractos Vegetales/farmacología, Sueño/efectos de los fármacos
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Pharmacological screening of Ageratum conyzoides L. (mentrasto)

Yamamoto, Lucia A; Soldera, Janete C; Emim, José A. S; Godinho, Rosely O; Souccar, Caden; Lapa, Antonio J.
Mem. Inst. Oswaldo Cruz; 86 (supl.2), 1991
The pharmacological activities of a water extract (WE) of Ageratum conyzoides L, a plant populary known for its analgesic and anti-inflamatory properties, were studied in vivo and in vitro preparations. Oral administration (p.o.) of the water extract (WE, 0.1 to 5 g/Kg) to rats and mice induced quietness...
Ageratum, Antiinflamatorios, Analgesia, Plantas Medicinales
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Analgesic activity of a triterpene isolated from Scoparia dulcis L. (vassourinha)

Freire, Sonia M. F; Torres, Luce M. B; Roque, Nidia F; Souccar, Caden; Lapa, Antonio J.
Mem. Inst. Oswaldo Cruz; 86 (supl.2), 1991
Analgesic and anti-inflammatory activities of water (WE) and ethanolic (EE) extracts of Scoparia dulcis L. were investigated in rats and mice, and compared to the effects induced by Glutinol, a triterpene isolated by purification of EE. Oral adminsitration (p.o.) of either WE or EE (up to 2 g/Kg) did not...
Scoparia, Analgesia, Antiinflamatorios, Plantas Medicinales
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Efeito da idade e nível de treinamento na farmacocinética do flunixin meglumine em cavalos puro-sangue inglês
Effect of age and training status on pharmacokinecits of flunixin meglumine in thoroughbreds

Jensen, R. C; Fischer, J. H; CWik, M. J.
Hora vet; 10 (58), 1990
A maioria das comissöes de corridas proíbem a presença de qualquer substância estranha na saliva, no sangue e na urina na amostragem feita após a corrida. A identificaçäo de uma substância proibida resulta normalmente na perda de prêmios e suspensäo do treinador. Proprietários, treinadores e v...
Antiinflamatorios, Meglumina, Caballos

Fissuras lábio-palatais: estudo de caso-controle de fatoresde risco

Loffredo, Leonor de Castro Monteiro.
As fissuras orais integram dois grupos segundo origens etiológicas distintas, quais sejam, fissuras labiais ou lábio-palatais e fissuras palatais. Realizou-se um estudo tipo caso-controle, com 450 casos e 450 controles, sendo, que, entre os casos, 354 eram portadores de fissura labial ou lábio-palatin...
Labio Leporino/epidemiología, Fisura del Paladar/epidemiología, Factores de Riesgo, Epilepsia/complicaciones, Antiinflamatorios/efectos adversos, Anomalías Inducidas por Medicamentos, Estudios de Casos y Controles, Brasil