Results: 723

Evaluación de estrés oxidativo en pacientes con Lupus Eritematoso Sistémico y su posible relación con la exposición ambiental a agroquímicos

Acta toxicol. argent; 24 (1), 2016
Los agroquímicos son un método efectivo para controlar especies perjudiciales a los intereses del hombre, pero aplicados indiscriminadamente provocan diversos impactos a nivel ambiental y en la salud. Uno de los mecanismos más importantes por el cual los agroquímicos se ponen en contacto directo con ...

The protective cardiac effects of Β-myrcene after global cerebral ischemia/reperfusion in C57BL/J6 mouse

Acta cir. bras; 31 (7), 2016
ABSTRACT PURPOSE: To investigate the protective effect of β-myrcene (MYR) on oxidative and histological damage in mice heart tissue caused global cerebral ischemia/reperfusion (IR) in C57BL/J6 mice. METHODS: Animals(n=40) were randomly divided into four groups: (1)control, (2)IR, (3)MYR and (4)MYR...

Nitric oxide and asymmetric dimethyl arginine (ADMA) levels in an experimental hydronephrotic kidney caused by unilateral partial ureteral obstruction

Int. braz. j. urol; 42 (3), 2016
ABSTRACT Aim Our aim is to measure asymmetric dimethyl arginine and nitric oxide levels in rats with induced unilateral acute ureteral obstruction to research the effects on the kidney. Material and Methods The study included 21 adolescent (average age 6 weeks) Sprague-Dawley male rats weighing betwe...

Metabolic syndrome and prostatic disease: potentially role of polyphenols in preventive strategies. A review

Int. braz. j. urol; 42 (3), 2016
ABSTRACT Benign prostatic hyperplasia and prostate cancer are two common urological diseases of the elderly. Scientific community has always looked for a link that could explain the correlation between the two diseases and the role of chronic inflammation in the pathogenesis of BPH and PCa. As shown by t...

Effect of lecithin on oxidative stress in an experimental model of rats colitis induced by acetic acid

Ulcerative colitis (UC) is an inflammatory disease that affects the bowels. Reactive oxygen species (ROS) are involved in the progress of UC. Objective: Evaluate the antioxidant effect of lecithin in an experimental model of acute UC induced by administration of acetic acid (AA) in rats. Methods: Lecit...

Biomarcadores inflamatórios e de estresse oxidativo em cadelas submetidas à ovário-histerectomia videoassistida ou convencional

A videocirurgia é atualmente uma das principais ferramentas operatórias, com vantagens que incluem menor estresse, incisões e dor pós-operatória quando comparada aos procedimentos abertos. Objetivou-se comparar o processo inflamatório e o estresse oxidativo resultantes das técnicas de ovário-hist...

Ursolic acid attenuates beta-amyloid-induced memory impairment in mice

Arq. neuropsiquiatr; 74 (6), 2016
ABSTRACT Objective Increasing evidence demonstrates that oxidative stress and inflammatory are involved in amyloid β (Aβ)-induced memory impairments. Ursolic acid (UA), a triterpenoid compound, has potent anti-inflammatory and antioxidant activities. However, it remains unclear whether UA atte...

Liver proteome of mice with different genetic susceptibilities to the effects of fluoride

J. appl. oral sci; 24 (3), 2016
ABSTRACT A/J and 129P3/J mice strains have been widely studied over the last few years because they respond quite differently to fluoride (F) exposure. 129P3/J mice are remarkably resistant to the development of dental fluorosis, despite excreting less F in urine and having higher circulating F levels. T...

The effects of supplemental melatonin administration on the healing of bone defects in streptozotocin-induced diabetic rats

J. appl. oral sci; 24 (3), 2016
ABSTRACT Diabetes mellitus (DM) causes an increased production of free radicals that can impair bone healing. Melatonin is a hormone secreted mainly by the pineal gland, which participates in the neutralization process of free radicals. Objective The aim of this study was to investigate histologic and ...

Priming previne a insuficiência renal aguda nefrotóxica através da estimulação do mecanismo de defesa antioxidante

J. bras. nefrol; 38 (2), 2016
RESUMO Introdução: Priming é um mecanismo de proteção induzida pela exposição anterior de uma célula ou órgão a baixas ou mesmas concentrações de uma substância tóxica. Objetivo: analisar o mecanismo de priming induzido pela exposição a gentamicina em células tubulares proximais humana...