Introduction: Human parechovirus (HPeV) belongs to the Picornaviridae family and has been described in viral meningoencephalitis and sepsis like illness in infants. Until now, 16 genotypes have been recognized, the most common are HPEV 1, 2 and 3; type 3 is most severe. Aims: To estimate the frequency of...
Nogueira, Glaucia R;
Azevedo, Paula S;
Polegato, Bertha F;
Zornoff, Leonardo AM;
Paiva, Sergio AR;
Nogueira, Celia R;
Araujo, Natalia C;
Carmona, Bruno HM;
Conde, Sandro J;
Minicucci, Marcos F.
OBJECTIVE: The aim of this study was to evaluate the roles of the Taql and Bsml vitamin D receptor gene polymorphisms in hospital mortality of burn patients. METHODS: In total, 105 consecutive burn injury patients over 18 years in age who were admitted to the Burn Unit of Bauru State Hospital from Janua...
Quemaduras/genética,
Quemaduras/mortalidad,
Creatinina/sangre,
Genotipo,
Mortalidad Hospitalaria,
Tiempo de Internación,
Modelos Logísticos,
Análisis Multivariante,
Polimorfismo Genético,
Potasio/sangre,
Estudios Prospectivos,
Receptores de Calcitriol/genética,
Factores de Riesgo,
Albúmina Sérica,
Sodio/sangre,
Urea/sangre
ABSTRACT Increased matrix metalloproteinases (MMPs) activity is a hallmark of periapical granulomas. However, the factors underlying the MMPs expression modulation in healthy and diseased periapical tissues remains to be determined. Objective In this study, we evaluated the association between the MMP1...
Estudios de Casos y Controles,
Citocinas/análisis,
Citocinas/genética,
Estudios de Asociación Genética,
Marcadores Genéticos,
Genotipo,
Metaloproteinasa 1 de la Matriz/análisis,
Metaloproteinasa 1 de la Matriz/genética,
Enfermedades Periapicales/genética,
Granuloma Periapical/genética,
Polimorfismo Genético,
Reacción en Cadena en Tiempo Real de la Polimerasa,
Valores de Referencia,
Análisis de Regresión,
Factores de Riesgo,
Estadísticas no Paramétricas,
Regulación hacia Arriba
Fundamento: A síndrome coronariana aguda (SCA) é a principal causa de morbidade e mortalidade no mundo. É uma doença multifatorial causada por obstrução das artérias coronárias por placa ateromatosa que leva à isquemia cardíaca. Diversos estudos sugerem que alguns polimorfismos ...
Background: Renal function declines according to age and vascular risk factors, whereas few data are available regarding geneticallymediated effects of anti-hypertensives over renal function. Objective: To estimate urea and creatinine variations in dementia due to Alzheimer disease (AD) by way of a pharm...
Enfermedad de AlzheimerSangre,
Inhibidores de la Enzima Convertidora de Angiotensina/farmacología,
CreatininaSangre,
Peptidil-Dipeptidasa A/genética,
UreaSangre,
Factores de Edad,
Alelos,
Presión Sanguínea/efectos de los fármacos,
Presión Sanguínea/genética,
AyunoSangre,
Frecuencia de los Genes,
Genotipo,
Hipertensión/tratamiento farmacológico,
Hipertensión/genética
Abstract: INTRODUCTION: The spread of multidrug-resistant Pseudomonas aeruginosa in Brazilian hospitals has greatly impacted upon the morbidity and mortality of individuals in intensive care units. Given the lack of information regarding the dynamics of multidrug resistance in northern Brazil, we analyz...
Infección Hospitalaria/microbiología,
Resistencia a Múltiples Medicamentos,
Antibacterianos/farmacología,
Brasil,
Estudios de Cohortes,
Genotipo,
Unidades de Cuidados Intensivos,
Pruebas de Sensibilidad Microbiana,
Persona de Mediana Edad,
Reacción en Cadena de la Polimerasa,
Infecciones por Pseudomonas/microbiología,
Pseudomonas aeruginosa/efectos de los fármacos,
Pseudomonas aeruginosa/enzimología,
Pseudomonas aeruginosa/genética,
Estudios Retrospectivos,
beta-Lactamasas/genética
CONTEXT AND OBJECTIVES: Glycoprotein inhibitors (abciximab, eptifibatide and tirofiban) are used in patients with unstable angina and non-ST-segment elevation myocardial infarction before percutaneous coronary intervention. Of these, tirofiban is the least effective. We hypothesized that the response to...
Abciximab,
Síndrome Coronario Agudo/tratamiento farmacológico,
Síndrome Coronario Agudo/genética,
Angina Inestable/tratamiento farmacológico,
Angina Inestable/genética,
Anticuerpos Monoclonales/uso terapéutico,
Eptifibatida,
Genotipo,
Fragmentos Fab de Inmunoglobulinas/uso terapéutico,
Mutación,
Péptidos/uso terapéutico,
Agregación Plaquetaria/efectos de los fármacos,
Agregación Plaquetaria/genética,
Inhibidores de Agregación Plaquetaria/uso terapéutico,
Complejo GPIIb-IIIa de Glicoproteína Plaquetaria/antagonistas & inhibidores,
Complejo GPIIb-IIIa de Glicoproteína Plaquetaria/genética,
Glicoproteínas de Membrana Plaquetaria/genética,
Reacción en Cadena de la Polimerasa,
Estudios Prospectivos,
Tirofibán,
Tirosina/análogos & derivados,
Tirosina/uso terapéutico
Abstract Giardia duodenalis is divided into eight assemblages (named A to H). Isolates of assemblage A are divided into four sub-assemblages (AI, AII, AIII and AIV). While isolates of sub-assemblage AII are almost exclusively detected in human hosts, isolates of assemblage B are encountered in a multitud...
Abstract β-Defensin-1, an antimicrobial peptide encoded by the DEFB1 gene, is known to play an important role in lung mucosal immunity. In our association study we analyzed three DEFB1 functional polymorphisms -52G>A (rs1799946), -44C>G (rs1800972) and -20G>A (rs11362) in 92 tuberculosis pa...
ABSTRACT This article provides a review of immunity, diagnosis, and clinical aspects of rotavirus disease. It also informs about the changes in epidemiology of diarrheal disease and genetic diversity of circulating group A rotavirus strains following the introduction of vaccines. Group A rotavirus is the...
Gastroenteritis/virología,
Infecciones por Rotavirus,
Rotavirus,
Brasil/epidemiología,
Diarrea/virología,
Gastroenteritis/terapia,
Gastroenteritis/inmunología,
Gastroenteritis/veterinaria,
Variación Genética,
Genotipo,
Rotavirus/genética,
Rotavirus/patogenicidad,
Rotavirus/fisiología,
Infecciones por Rotavirus/fisiopatología,
Infecciones por Rotavirus/terapia,
Infecciones por Rotavirus/transmisión,
Infecciones por Rotavirus/veterinaria,
Vacunas contra Rotavirus/inmunología,
Vacunas contra Rotavirus/uso terapéutico,
Zoonosis/transmisión,
Zoonosis/virología
