Background: The association of obesity with endometrial cancer is supported by the presence of endoplasmic reticulum (ER) stress in the adipocyte. Glucose-regulated protein 78 (GRP78) is a marker for ER stress. This protein is a central regulator of ER stress due to its major anti-apoptotic role. It play...
ABSTRACT Objective Parathyroid cancer (PC) represents < 1% of cases of PHPT. Tumors demonstrating atypical histopathologic features and don’t fulfill criteria for carcinoma are classified as atypical adenomas (APA). The purpose of this study was to determine a biochemical or ultrasonographic f...
Adenoma/sangre,
Adenoma/diagnóstico por imagen,
Adenoma/patología,
Adenoma/cirugía,
Fosfatasa Alcalina/sangre,
Biomarcadores de Tumor/sangre,
Calcio/sangre,
Calcio/orina,
Estudios de Casos y Controles,
Hormona Paratiroidea/sangre,
Neoplasias de las Paratiroides/sangre,
Neoplasias de las Paratiroides/diagnóstico por imagen,
Neoplasias de las Paratiroides/patología,
Neoplasias de las Paratiroides/cirugía,
Valor Predictivo de las Pruebas,
Cuidados Preoperatorios,
Ultrasonografía/métodos
Yuksel, Ozgur Haki;
Verit, Ayhan;
Sahin, Aytac;
Urkmez, Ahmet;
Uruc, Fatih;
Demirer, Zafer;
Güragac, Ali;
Uguz, Sami;
Uslu, Ali Ugur;
Zor, Murat.
Abstract Introduction: Data from animal, clinical and prevention studies support the role of androgens in prostate cancer growth, proliferation and progression. Results of serum based epidemiologic studies in humans, however, have been inconclusive. The present study aims to define whether serum testost...
Biomarcadores de Tumor/sangre,
Biopsia/métodos,
Persona de Mediana Edad,
Valor Predictivo de las Pruebas,
Próstata/patología,
Antígeno Prostático Específico/sangre,
Neoplasia Intraepitelial Prostática/sangre,
Neoplasia Intraepitelial Prostática/patología,
Neoplasias de la Próstata/sangre,
Neoplasias de la Próstata/patología,
Estándares de Referencia,
Valores de Referencia,
Factores de Riesgo,
Testosterona/sangre
ABSTRACT Background: Bladder cancer represents one of the most important clinical challenges in urologic practice. In this context, inflammation has an important role in the development and progression of many malignancies. The objective of the present study was to evaluate the prognostic value of pre-t...
Biomarcadores de Tumor/sangre,
Recuento de Células Sanguíneas,
Supervivencia sin Enfermedad,
Estudios de Seguimiento,
Italia/epidemiología,
Recuento de Leucocitos,
Recuento de Linfocitos,
Linfocitos,
Invasividad Neoplásica,
Neutrófilos,
Pronóstico,
Análisis de Supervivencia,
Neoplasias de la Vejiga Urinaria/sangre,
Neoplasias de la Vejiga Urinaria/mortalidad,
Neoplasias de la Vejiga Urinaria/patología
ABSTRACT Objective Prolactin is a multifunctional pituitary hormone. The effect of prolactin on platelet activation is not well understood. Prolactinomas are the most common type of pituitary adenomas, and they are medically responsive to dopamine agonists. Mean platelet volume (MPV) is a marker of pla...
Biomarcadores de Tumor/sangre,
Cabergolina,
Estudios de Casos y Controles,
Agonistas de Dopamina/uso terapéutico,
Ergolinas/uso terapéutico,
Volúmen Plaquetario Medio,
Neoplasias Hipofisarias/sangre,
Neoplasias Hipofisarias/tratamiento farmacológico,
Prolactinoma/sangre,
Prolactinoma/tratamiento farmacológico,
Valores de Referencia,
Estudios Retrospectivos,
Factores de Tiempo,
Resultado del Tratamiento
ABSTRACT Abstract Purpose:To evaluate the effect of ejaculation on serum prostate-specific antigen (PSA) concentrations in patients with lower urinary tract symptom (LUTS). Materials and Methods Our study includes 98 men (62 study and 36 control). After three days of sexual abstinence, blood samples ...
Análisis de Varianza,
Biomarcadores de Tumor/sangre,
Estudios de Casos y Controles,
Eyaculación/fisiología,
Síntomas del Sistema Urinario Inferior/sangre,
Persona de Mediana Edad,
Estudios Prospectivos,
Antígeno Prostático Específico/sangre,
Neoplasias de la Próstata/sangre,
Estándares de Referencia,
Valores de Referencia,
Factores de Tiempo
ABSTRACT Background - Human epidermal growth factor receptor 2 (EGFR2/HER2/ErbB2) is a transmembrane receptor that stimulates cell proliferation when activated. The correlation of HER2 expression with prognosis has been studied in many cancer types. However, its relationship with survival of patients ...
Protocolos de Quimioterapia Combinada Antineoplásica/uso terapéutico,
Biomarcadores de Tumor/sangre,
Supervivencia sin Enfermedad,
Inmunohistoquímica,
Persona de Mediana Edad,
Pronóstico,
Receptor ErbB-2/sangre,
Receptor ErbB-2/metabolismo,
Estudios Retrospectivos,
Neoplasias Gástricas/sangre,
Neoplasias Gástricas/tratamiento farmacológico,
Neoplasias Gástricas/patología,
Resultado del Tratamiento
ABSTRACT Purpose The aim of the study was to investigate white blood cell counts and neutrophil to lymphocyte ratio (NLR) as markers of systemic inflammation in the diagnosis of localized testicular cancer as a malignancy with initially low volume. Materials and Methods Thirty-six patients with local...
Biomarcadores de Tumor/sangre,
Estudios de Casos y Controles,
Hemoglobinas/análisis,
Recuento de Linfocitos,
Linfocitos,
Persona de Mediana Edad,
Neoplasias de Células Germinales y Embrionarias/sangre,
Neoplasias de Células Germinales y Embrionarias/diagnóstico,
Neoplasias de Células Germinales y Embrionarias/patología,
Neutrófilos,
Pronóstico,
Curva ROC,
Valores de Referencia,
Reproducibilidad de los Resultados,
Estudios Retrospectivos,
Estadísticas no Paramétricas,
Neoplasias Testiculares/sangre,
Neoplasias Testiculares/diagnóstico,
Neoplasias Testiculares/patología,
Carga Tumoral,
Varicocele/sangre
PURPOSE: This paper describes the ability of miRNA value predict oncological outcomes in CRC patients and correlates to clinical and pathologic variables. METHODS: We prospectively analyzed the serological expression of microRNA-21, microRNA-34a, and microRNA-126 in 37 stage II - IV CRC patients and co...
Adenoma/sangre,
Carcinoma/sangre,
Neoplasias Colorrectales/sangre,
MicroARNs/sangre,
Adenoma/genética,
Factores de Edad,
Biomarcadores de Tumor/sangre,
Antígeno Carcinoembrionario/sangre,
Carcinoma/genética,
Estudios de Casos y Controles,
Neoplasias Colorrectales/genética,
Recurrencia Local de Neoplasia,
Estadificación de Neoplasias,
Pronóstico,
Estudios Prospectivos,
Reacción en Cadena en Tiempo Real de la Polimerasa,
Valores de Referencia
