OBJECTIVE: To compare the efficacy and safety of sedation with midazolam vs dexmedetomidine in patients with high probability of obstructive sleep apnea, to assess hemodynamic parameters, ventilation and depth of hypnosis. METHODS: Patients scheduled to regional anesthesia and sedation participated in th...
Joubert syndrome (JS) is a rare autosomal recessive disorder characterized by abnormal eye movements, respiratory pattern abnormalities, anatomical airway alterations, mental retardation and hypoplasia/aplasia of the cerebellar vermis confirmed by magnetic resonance imaging. This case report describes th...
We present a 38 years female patient with known difficult airway associated with an important anatomic deformation due to a tumoral removal back in 2014 (maxilectomy). This patient was scheduled for a new tumoral resection at the base of the skull, which was considered a potential regrowth of her maxilar...
Objetivos: Evaluar la efectividad de la infiltración del sitio quirúrgico, con ropivacaína, dexmedetomidina y ketorolac, en pacientes sometidos a instrumentación transpedicular dorsolumbar con técnica mini invasiva, en cuanto al consumo de opioides durante la internación.
Materiales y métodos: Se ...
Objetivou-se comparar os efeitos fisiológicos, analgésicos e sobre a taxa de infusão de propofol, decorrentes da anestesia epidural com lidocaína, associada ao tramadol ou à dexmedetomidina, em felinas submetidas à ovariosalpingohisterectomia (OSH). Para tal, 16 felinas hígidas foram pré-tratadas...
Abstract Purpose: To evaluate the effects of Dexmedetomidine (Dex) on spinal pathology and inflammatory factor in a rat model of Diabetic neuropathic pain (DNP). Methods: The rats were divided into 3 groups (eight in each group): normal group (N group), diabetic neuropathic pain model group (DNP group)...
Agonistas de Receptores Adrenérgicos alfa 2/farmacología,
Western Blotting,
Dexmedetomidina/farmacología,
Diabetes Mellitus Experimental/tratamiento farmacológico,
Diabetes Mellitus Experimental/patología,
Neuropatías Diabéticas/tratamiento farmacológico,
Neuropatías Diabéticas/patología,
Modelos Animales de Enfermedad,
Interleucina-1beta/análisis,
Interleucina-1beta/efectos de los fármacos,
Microscopía Electrónica de Transmisión,
Proteína con Dominio Pirina 3 de la Familia NLR/análisis,
Proteína con Dominio Pirina 3 de la Familia NLR/efectos de los fármacos,
Conducción Nerviosa/efectos de los fármacos,
Umbral del Dolor,
Distribución Aleatoria,
Receptores Purinérgicos P2X4/análisis,
Columna Vertebral/efectos de los fármacos,
Nervio Sural/efectos de los fármacos,
Factores de Tiempo
Abstract Objectives: Emergence agitation is a negative behavior commonly recorded after pediatric tonsillectomy. We investigated the efficacy of preoperative premedication with oral transmucosal buccal dexmedetomidine on the incidence and severity of emergence agitation in preschool children undergoing ...
Background: Pain is defined as "unpleasant sensory and sensory experience", associated with actual or potential tissue domage or described in terms of such damage. Objetive: To assess the effect of bupivacaine versus bupivacaine plus intrathecal dexmedetomidine in postoperative pain. Patients and method:...
Abstract Background and objectives One of the disadvantages of unilateral spinal anesthesia is the short duration of post-operative analgesia, which can be addressed by adding adjuvants to local anesthetics. The aim of current study was to compare the effects of adding dexmedetomidine, fentanyl, or sali...
Dexmedetomidine (DEX), a selective agonist of α2-adrenergic receptors, has anti-inflammation properties and potential beneficial effects against trauma, shock, or infection. Therefore, this study aimed to investigate whether DEX might protect against multiple-organ dysfunction in a two-hit model of ...
Biomarcadores/sangre,
Dexmedetomidina/uso terapéutico,
Modelos Animales de Enfermedad,
Endotoxemia/tratamiento farmacológico,
Endotoxemia/patología,
Hemorragia/tratamiento farmacológico,
Hemorragia/patología,
Insuficiencia Multiorgánica/tratamiento farmacológico,
Insuficiencia Multiorgánica/patología,
Estrés Oxidativo/efectos de los fármacos,
Sustancias Protectoras/uso terapéutico,
Ratas Wistar,
Receptores Adrenérgicos beta 2/efectos de los fármacos,
Receptores Adrenérgicos beta 2/metabolismo,
Resucitación,
Factores de Tiempo
