Adenocarcinoma/sangre,
Adenocarcinoma/diagnóstico,
Adenocarcinoma/economía,
Antígenos de Neoplasias/sangre,
Biomarcadores de Tumor/sangre,
Región del Caribe,
Análisis Costo-Beneficio,
Países en Desarrollo/economía,
Detección Precoz del Cáncer/economía,
América Latina,
Proteínas de Neoplasias/sangre,
Neoplasias de la Próstata/sangre,
Neoplasias de la Próstata/diagnóstico,
Neoplasias de la Próstata/economía,
Sensibilidad y Especificidad
ABSTRACT Objective: To investigate the diagnostic value of α-enolase (ENO1) and serum ENO1 autoantibody levels in lung cancer. Methods: Immunohistochemistry staining and ELISA were performed to detect ENO1 expression in lung tissue and serum ENO1 autoantibody levels, respectively. Results: The ex...
Autoanticuerpos/sangre,
Biomarcadores de Tumor/análisis,
Carcinoma/diagnóstico,
Carcinoma/enzimología,
Carcinoma/patología,
Ensayo de Inmunoadsorción Enzimática,
Inmunohistoquímica,
Neoplasias Pulmonares/diagnóstico,
Neoplasias Pulmonares/enzimología,
Neoplasias Pulmonares/patología,
Fosfopiruvato Hidratasa/análisis,
Valores de Referencia,
Sensibilidad y Especificidad,
Estadísticas no Paramétricas
ABSTRACT Objective: To evaluate the value of soluble urokinase-type plasminogen activator receptor (suPAR) in the diagnosis of acute exacerbation of COPD (AECOPD) and in monitoring treatment response, analyzing the relationship between suPAR and fibrinogen in AECOPD. AECOPD leads to increased airway inf...
Enfermedad Aguda,
Biomarcadores/sangre,
Análisis de los Gases de la Sangre,
Estudios de Casos y Controles,
Ensayo de Inmunoadsorción Enzimática,
Fibrinógeno/análisis,
Enfermedad Pulmonar Obstructiva Crónica/sangre,
Enfermedad Pulmonar Obstructiva Crónica/diagnóstico,
Enfermedad Pulmonar Obstructiva Crónica/terapia,
Receptores del Activador de Plasminógeno Tipo Uroquinasa/sangre,
Valores de Referencia,
Pruebas de Función Respiratoria,
Sensibilidad y Especificidad,
Factores de Tiempo,
Resultado del Tratamiento
Abstract Objective: To assess the applicability of salivary C-reactive protein, mean platelet volume, neutrophil-lymphocyte ratio, and platelet lymphocyte ratio in the diagnosis of neonatal sepsis. Methods: Prospective case-control study of 70 full-term neonates, 35 with sepsis (20 with proven sepsis a...
Biomarcadores/análisis,
Proteína C-Reactiva/análisis,
Estudios de Casos y Controles,
Ensayo de Inmunoadsorción Enzimática,
Recuento de Linfocitos,
Volúmen Plaquetario Medio,
Sepsis Neonatal/diagnóstico,
Neutrófilos/citología,
Estudios Prospectivos,
Curva ROC,
Saliva/química,
Sensibilidad y Especificidad
Abstract Objective: Diagnosis of central precocious puberty has always been challenging in clinical practice. As an important method in the diagnosis of central precocious puberty, luteinizing hormone-releasing hormone stimulation test is complex and time-consuming. In many cases, clinical traits are in...
Abstract Objective: To assess the performance of cerebrospinal fluid (CSF) lactate as a biomarker to differentiate bacterial meningitis from viral meningitis in children, and to define an optimal CSF lactate concentration that can be called significant for the differentiation. Methods: Children with cl...
Background: Early recognition of rheumatoid arthritis (RA) provides clinical benefits in terms of remission induction, reduced disease progression, and eventually treatment free remission. Aim: To describe the setting of a Unit devoted exclusively to the recognition and treatment of early RA in patients...
Artritis Reumatoide/diagnóstico,
Atención Integral de Salud,
Diagnóstico Precoz,
Artritis Reumatoide/terapia,
Chile,
Accesibilidad a los Servicios de Salud,
Atención Primaria de Salud,
Enfermedades Reumáticas/clasificación,
Enfermedades Reumáticas/diagnóstico,
Enfermedades Reumáticas/terapia,
Sensibilidad y Especificidad
Background: International guidelines suggest a screening panel for monoclonal gammopathies that contains serum protein electrophoresis (SPE), free light chain (FLC) measurements and immunofixation. This combination provides the possibility of a timely accurate diagnosis. Aim: To evaluate the sensibility...
Abstract Introduction: Despite having higher sensitivity as compared to conventional troponins, sensitive troponins have lower specificity, mainly in patients with renal failure. Objective: Study aimed at assessing the sensitive troponin I levels in patients with chest pain, and relating them to the ex...
Abstract Serological testing and culling infected animals are key management practices aiming eradication of bovine leukemia virus infection. Here, we report the development of an indirect ELISA based on BLV recombinant capsid protein (BLVp24r) to detect anti-BLV antibodies in cattle serum. The BLVp24r w...
Anticuerpos Antivirales/sangre,
Proteínas de la Cápside/análisis,
Proteínas de la Cápside/genética,
Proteínas de la Cápside/inmunología,
Leucosis Bovina Enzoótica/sangre,
Leucosis Bovina Enzoótica/diagnóstico,
Leucosis Bovina Enzoótica/virología,
Ensayo de Inmunoadsorción Enzimática/instrumentación,
Ensayo de Inmunoadsorción Enzimática/métodos,
Virus de la Leucemia Bovina/genética,
Virus de la Leucemia Bovina/inmunología,
Virus de la Leucemia Bovina/aislamiento & purificación,
Proteínas Recombinantes/análisis,
Proteínas Recombinantes/genética,
Proteínas Recombinantes/inmunología,
Sensibilidad y Especificidad,
Pruebas Serológicas/métodos
