Results: 723

Antioxidant and anticholinesterase investigations of Rumex hastatus D. Don: potential effectiveness in oxidative stress and neurological disorders

Biol. Res; 48 (), 2015
BACKGROUND: Rumex species are traditionally used for the treatment of neurological disorders including headache, migraine, depression, paralysis etc. Several species have been scientifically validated for antioxidant and anticholinestrase potentials. This study aims to investigate Rumex hastatus D. Don c...

Anticholinesterse and antioxidant investigations of crude extracts, subsequent fractions, saponins and flavonoids of atriplex laciniata L: potential effectiveness in Alzheimer's and other neurological disorders

Biol. Res; 48 (), 2015
BACKGROUND: Atriplex laciniata L. was investigated for phenolic, flavonoid contents, antioxidant, anticholinesterase activities, in an attempt to explore its effectiveness in Alzheimer's and other neurological disorders. Plant crude methanolic extract (Al.MeF), subsequent fractions; n-hexane (Al.HxF), ch...

Mechanisms involved in reproductive damage caused by gossypol in rats and protective effects of vitamin E

Biol. Res; 48 (), 2015
BACKGROUND: Gossypol is a chemical present in the seeds of cotton plants (Gossypium sp.) that reduces fertility in farm animals. Vitamin E is an antioxidant and may help to protect cells and tissues against the deleterious effects of free radicals. The aim of this study was to evaluate the mechanisms of ...

Wine grape pomace flour improves blood pressure, fasting glucose and protein damage in humans: a randomized controlled trial

Biol. Res; 48 (), 2015
BACKGROUND: The Mediterranean diet is a healthy diet with positive scientific evidence of preventing chronic diseases. Bioactive components support the healthy properties of the Mediterranean diet. Antioxidants and fiber, two components of the Mediterranean diet, are key functional nutrients for healthy ...

Antioxidant and anti hyperglycemic role of wine grape powder in rats fed with a high fructose diet

Biol. Res; 48 (), 2015
BACKGROUND: Metabolic syndrome is a growing worldwide health problem. We evaluated the effects of wine grape powder (WGP), rich in antioxidants and fiber, in a rat model of metabolic syndrome induced by a high fructose diet. We tested whether WGP supplementation may prevent glucose intolerance and decrea...

Antiproliferative activity of marine stingray Dasyatis sephenvenom on human cervical carcinoma cell line

BackgroundVenoms comprise mixtures of numerous bioactive compounds that have a wide range of pharmacologic actions. Toxins from venomous animals have attracted the attention of researchers because of their affinity for primary sites responsible for lethality and their efficacy at extremely low concentrat...

Complicaciones de la diabetes y su asociación con el estrés oxidativo: un viaje hacia el daño endotelial

Rev. colomb. cardiol; 21 (6), 2014
La diabetes es un trastorno metabólico que se ha incrementado en Latinoamérica y Venezuela en la última década. Ejerce una influencia considerable en la morbimortalidad de las enfermedades cardiovasculares debido al desequilibrio hidrocarbon ado y a los pacientes fuera de los objetivos de la Asociaci...

Peroxidação lipídica em cabras com anemia e doença respiratória tratadas com ferro por via parenteral

Pesqui. vet. bras; 34 (11), 2014
Objetivou-se avaliar a progressão da doença e o dano oxidativo em cabras com anemia e doença respiratória mediante aplicação de ferro parenteral. Foram estudadas seis cabras, adultas, com parâmetros eritrocitários indicativos e anemia e manifestações de doença respiratória (tosse, espirros e ...

Óxido nítrico e arginina di-metil assimétrica: possível via de explicação para o trabalho de parto pré-termo

Femina; 42 (4), 2014
O trabalho de parto pré-termo (TPPT) assim como as outras causas de prematuridade respondem pela maior parcela da mortalidade e morbidade neonatal no mundo. Várias vias metabólicas já foram estudadas e diversas alterações já foram encontradas em pacientes que desenvolve TPPT. A via metabólica do ...

Efeitos do consumo de castanha-do-brasil ( Bertholetia excelsa H. B. K. ) sobre o estresse oxidativo em pacientes com comprometimento cognitivo leve e a relação com variações em genes de selenoproteínas

Visto que o estresse oxidativo está intimamente relacionado com a progressão da demência, este se apresenta como um possível alvo terapêutico a fim de preservar as funções cognitivas. No mesmo sentido, estudos mostram o papel antioxidante do selênio, mineral que atua por meio das selenoproteínas...