Abstract The purpose of this study is to evaluate the effect of the avocado/soybean unsaponifiables (ASU) on the treatment of induced periodontitis in rats. Periodontitis was induced in 84 rats via ligature placement around the second upper molar, which was removed after 7 days, and scaling and root plan...
Expresión Génica,
Inmunohistoquímica,
Interleucina-1beta/análisis,
Interleucina-6/análisis,
Periodontitis/tratamiento farmacológico,
Periodontitis/etiología,
Periodontitis/patología,
Persea/química,
Extractos Vegetales/uso terapéutico,
Ligando RANK/análisis,
Distribución Aleatoria,
Ratas Sprague-Dawley,
Reacción en Cadena en Tiempo Real de la Polimerasa,
Valores de Referencia,
Reproducibilidad de los Resultados,
Aplanamiento de la Raíz/métodos,
Glycine max/química,
Fosfatasa Ácida Tartratorresistente/análisis,
Factores de Tiempo,
Resultado del Tratamiento,
Factor de Necrosis Tumoral alfa/análisis
Abstract The aim of this study was to evaluate edemogenic activity and subcutaneous inflammatory reaction induced by Psidium cattleianum leaf extracts associated with Ca(OH)2. Thirty male Wistar rats, split equally into three groups [aqueous extract + Ca(OH)2; ethanolic extract + Ca(OH)2; and propylene g...
Antiinfecciosos/farmacología,
Hidróxido de Calcio/farmacología,
Portadores de Fármacos,
Evaluación Preclínica de Medicamentos,
Etanol/farmacología,
Inflamación/tratamiento farmacológico,
Inflamación/patología,
Ensayo de Materiales,
Vehículos Farmacéuticos/química,
Vehículos Farmacéuticos/farmacología,
Extractos Vegetales/farmacología,
Hojas de la Planta/química,
Propilenglicol/farmacología,
Psidium/química,
Ratas Wistar,
Reproducibilidad de los Resultados,
Tejido Subcutáneo/efectos de los fármacos,
Tejido Subcutáneo/patología,
Factores de Tiempo,
Agua/química
BACKGROUND: The Tridax procumbens extracts (TPE) are known for their ethno-medicinal properties to increase osteogenic functioning in mesenchymal stem cells. Recently, we found that the T. procumbens flavonoids (TPF) significantly suppressed the RANKL-induced osteoclasts differentiation and bone resorpti...
Asteraceae/química,
Densidad Ósea/efectos de los fármacos,
Resorción Ósea/tratamiento farmacológico,
Diferenciación Celular/efectos de los fármacos,
Flavonoides/farmacología,
Osteogénesis/efectos de los fármacos,
Extractos Vegetales/farmacología,
Resorción Ósea/patología,
Flavonoides/aislamiento & purificación,
Osteoblastos/citología,
Osteoblastos/efectos de los fármacos,
Ratones Endogámicos C57BL
The aim of this study is to investigate the effectiveness of intravenous administration of Berberis vulgaris root bark aqueous extract (BRBD) on the cardiovascular and renal functions of healthy normotensive rats. The different doses of BRBD 1, 10 and 20 mg/kg were administered intravenously (i.v) in nor...
ABSTRACT Anisophyllea laurina is a plant that has been used in folk medicine to treat malaria, dysentery, diabetes, toothache and various skin diseases. Leaves extract had protein content of 9.68% and a high calcium content of 25084.317 mg/100 g while stem bark extract was found to contain greater amount...
ABSTRACT The dichloromethane extract of Plectranthus ornatus Codd., a tradicional medicinal plant, showed antibiotic activity with minimum inhibitory concentration (MIC) values of 0.4 mg.mL-1 and 100 percent of biofilm inhibition against Staphylococcus aureus strains isolated from animals with mastitis i...
Antibacterianos/farmacología,
Bovinos,
Mastitis Bovina,
Pruebas de Sensibilidad Microbiana,
Extractos Vegetales/farmacología,
Plantas Medicinales/química,
Plantas Medicinales/clasificación,
Plectranthus/química,
Plectranthus/clasificación,
Staphylococcus aureus/efectos de los fármacos,
Staphylococcus aureus/aislamiento & purificación
PINTO, NÍCOLAS C C;
SILVA, JUCÉLIA B;
MENEGATI, LAURA M;
GUEDES, MARIA CLARA M R;
MARQUES, LUCAS B;
SILVA, THIAGO P DA;
MELO, ROSSANA C N DE;
SOUZA-FAGUNDES, ELAINE M DE;
SALVADOR, MARCOS J;
SCIO, ELITA;
FABRI, RODRIGO L.
ABSTRACT This study aimed to further investigate the cytotoxicity against tumor cell lines and several bacterial strains of Annona squamosa and its mode of action. Methanol extracts of A. squamosa leaves (ASL) and seeds (ASS) were used. ASL showed significant antibacterial activity against S. aureus, K. ...
ABSTRACT The purpose of this study was to evaluate the antiproliferative and antigenotoxic activity of Sambucus australis Cham. & Schltdl. aqueous extracts on the cell cycle of Allium cepa L. as well as determine the phenolic compounds in such extracts. S. australis inflorescences and leaves of two a...
Adoxaceae/química,
Antioxidantes/análisis,
Antioxidantes/farmacología,
Flavonoides/química,
Fenoles/análisis,
Fitoquímicos/análisis,
Extractos Vegetales/química,
Extractos Vegetales/farmacología,
Hojas de la Planta/química,
Sambucus/química,
Agua/análisis
ABSTRACT The in vitro metabolism of a widespread natural product, trachyloban-19-oic acid (1), by the fungal species Mucor plumbeus was studied in a sucrose-yeast liquid medium. Two products were isolated, and their structures were determined by spectroscopic means as 7β-hydroxytrachyloban-19-oic ac...
FREITAS, EDNARDO R;
FERNANDES, DANILO R;
SOUZA, DAVYD H;
DANTAS, FRANCISCO D T;
SANTOS, REBECA C;
OLIVEIRA, GILSON B;
CRUZ, CARLOS EDUARDO B;
BRAZ, NÁDIA M;
CÂMARA, LORENA F;
NASCIMENTO, GERMANO A J;
WATANABE, PEDRO H.
ABSTRACT The aim of this study was to evaluate the effect of Syzygium cumini leaves (SCL) in laying hens diets on productive performance, egg quality and lipid oxidation of yolk. A total of 108 Hysex White laying hens were distributed in a completely randomized design with three treatments and six replic...
Alimentación Animal/análisis,
Fenómenos Fisiológicos Nutricionales de los Animales,
Brasil,
Pollos/fisiología,
Dieta,
Suplementos Dietéticos/análisis,
Cáscara de Huevo,
Yema de Huevo,
Oviposición/efectos de los fármacos,
Extractos Vegetales/análisis,
Hojas de la Planta,
Syzygium
