This study compared the thermal changes of cutaneous and subcutaneous tissues exposed to different aerosols. Thirty-six adults Wistar rats were arranged in two treatment groups, one exposed to methyl salicylate (GSM; n = 9 skin and n = 9 subcutaneous) and the other exposed to diclofenac diethylammonium (...
This study investigated the effects of ultrasound therapy on haematological dynamics and plasma fibrinogen during the inflammatory phase of muscle injury. Forty-eight male Wistar rats were divided into control group (CG), continuous ultrasound treated group (CTU) and pulsed ultrasound (PTU). Animals were...
A artrite reumatoide (AR) é uma doença inflamatória crônica, caracterizada por inflamação das articulações e se manifesta por inchaço e incapacidade funcional das mesmas. A patologia da doença envolve a produção excessiva de radicais livres pelos neutrófilos ativados, podendo induzir à pero...
Introdução: A formação do Cisto Radicular (CR) está associada à proliferação dos restos epiteliais de Malassez por estímulos inflamatórios, provenientes da proliferação bacteriana do canal radicular de um dente não vital. Quando o dente é removido, esse cisto passa a ser denominado Cisto Re...
La aterosclerosis es el resultado de la alteración en la función del endotelio arterial, desencadenada por la exposición continua de este tejido a fenómenos circulatorios turbulentos. La presencia de factores de riesgo cardiovascular promueve la sobre-expresión de moléculas proinflamatorias que ini...
White adipose tissue (WAT) is considered an endocrine organ. When present in excess, WAT can influence metabolism via biologically active molecules. Following unregulated production of such molecules, adipose tissue dysfunction results, contributing to complications associated with obesity. Previous stud...
BACKGROUND: The current study aims at evaluating the analgesic, anti-pyretic and anti-inflammatory properties of methanolic extract of the stem, bark and leaves of Launaea sarmentosa and Aegialitis rotundifolia roxb. RESULTS: The AELS and AEAR extract presented a significant (***p < 0.001) dose dependent...
Antipiréticos/uso terapéutico,
Asteraceae/química,
Fiebre/tratamiento farmacológico,
Manejo del Dolor,
Fitoterapia,
Plumbaginaceae/química,
Analgésicos/uso terapéutico,
Antiinflamatorios no Esteroideos/uso terapéutico,
Aspirina/uso terapéutico,
Edema/inducido químicamente,
Edema/tratamiento farmacológico,
Indometacina/uso terapéutico,
Inflamación/tratamiento farmacológico,
Extractos Vegetales/uso terapéutico,
Hojas de la Planta/efectos de los fármacos,
Hojas de la Planta/metabolismo,
Bangladesh,
Ratas Wistar,
Factores de Tiempo,
Pruebas de Toxicidad Aguda
Diabetic retinopathy is one of the most important causes of blindness. The underlying mechanisms of this disease include inflammatory changes and remodeling processes of the extracellular-matrix (ECM) leading to pericyte and vascular endothelial cell damage that affects the retinal circulation. In turn, ...
Retinopatía Diabética/tratamiento farmacológico,
Inhibidores de Serina Proteinasa/uso terapéutico,
alfa 1-Antitripsina/uso terapéutico,
Antiinflamatorios/metabolismo,
Antiinflamatorios/uso terapéutico,
Movimiento Celular/fisiología,
Quimiotaxis/fisiología,
Retinopatía Diabética/fisiopatología,
Inflamación/metabolismo,
Mediadores de Inflamación/antagonistas & inhibidores,
FN-kappa B/metabolismo,
Neutrófilos/fisiología,
Óxido Nítrico Sintasa/antagonistas & inhibidores,
Sustancias Protectoras/metabolismo,
Receptores Proteinasa-Activados/metabolismo,
Inhibidores de Serina Proteinasa/metabolismo,
Factor de Necrosis Tumoral alfa/metabolismo,
alfa 1-Antitripsina/metabolismo,
Hipoxia de la Célula,
Radicales Libres
BACKGROUND: Despite Cryptostegia grandiflora Roxb. ex R. Br. (Apocynaceae) leaves are widely used in folk Caribbean Colombian medicine for their anti-inflammatory effects, there are no studies that support this traditional use. Therefore, this work aimed to evaluate the effect of the total extract and pr...
Antiinflamatorios/farmacología,
Apocynaceae/química,
Edema/tratamiento farmacológico,
Macrófagos/efectos de los fármacos,
Extractos Vegetales/uso terapéutico,
Línea Celular Tumoral/efectos de los fármacos,
Citotoxinas/farmacología,
Dinoprostona/análisis,
Inflamación/tratamiento farmacológico,
Óxido Nítrico/análisis,
Oxitócicos/análisis,
Peroxidasa/antagonistas & inhibidores,
Hojas de la Planta/química,
Ratones Endogámicos ICR