Abstract Purpose: To evaluate osteocalcin gene and protein expression in vitro and in an in vivo model of ostectomy. Methods: Twenty Wistar rats were assigned into two groups A (n=10, laser) and B (n=10, control). Ostectomy was performed in the femur diaphysis; the twenty fragments removed, composed in...
Fémur/metabolismo,
Fémur/efectos de la radiación,
Fémur/cirugía,
Expresión Génica/efectos de la radiación,
Inmunohistoquímica,
Terapia por Luz de Baja Intensidad,
Modelos Animales,
Osteocalcina/genética,
Osteocalcina/metabolismo,
Osteocalcina/efectos de la radiación,
Osteotomía,
Ratas Wistar
Abstract Purpose: To investigate cardiac changes in young rats, whose mothers underwent autogenic fecal peritonitis, during organogenesis phase and to evaluate the role of intravenous administration of moxifloxacin and dexamethasone in preventing infection-related cardiac changes. Methods: A prospecti...
Animales Recién Nacidos,
Dexametasona/administración & dosificación,
Modelos Animales de Enfermedad,
Fluoroquinolonas/administración & dosificación,
Corazón/efectos de los fármacos,
Moxifloxacino,
Miocardio/patología,
Organogénesis,
Peritonitis/complicaciones,
Peritonitis/tratamiento farmacológico,
Peritonitis/patología,
Complicaciones del Embarazo,
Estudios Prospectivos,
Ratas Wistar
Abstract Purpose: To evaluate whether pre-treatment with rivastigmine is able to attenuate the I/R induced lesions in rat liver. Methods: SHAM animals or those submitted to I/R, non-treated or pre-treated with rivastigminine (2mg/kg) either 50 or 15 minutes before ischemia, were used. After I/R proto...
Alanina Transaminasa/sangre,
Aspartato Aminotransferasas/sangre,
Modelos Animales de Enfermedad,
Isquemia/sangre,
Isquemia/complicaciones,
Hígado/irrigación sanguínea,
Hígado/efectos de los fármacos,
Mitocondrias Hepáticas,
Miopatías Mitocondriales/prevención & control,
Ratas Wistar,
Daño por Reperfusión/patología,
Daño por Reperfusión/prevención & control,
Rivastigmina/administración & dosificación
Costa-Filho, Octavio Antonio Azevedo da;
Costa, Mario Augusto Cray da;
Waaga-Gasser, Ana Maria;
Kubrusly, Luiz Fernando;
Oliveira, Luciane Bugmann Moreira de;
Collaço, Luiz Martins;
Magalhães, Maria Angélica Baron;
Gasser, Martin;
Malafaia, Osvaldo;
Ribas-Filho, Jurandir Marcondes.
Abstract Purpose: To compare wound healing performed with cold blade (CSB) and ultrasonic harmonic scalpel (UHS) in the abdominal aponeurosis of rats. Methods: Eighty Wistar rats divided into two groups and underwent midline incision in the linea alba with cold blade and harmonic ultrasonic scalpel. ...
Pared Abdominal/patología,
Pared Abdominal/cirugía,
Colágeno/fisiología,
Inmunohistoquímica,
Modelos Animales,
Ratas Wistar,
Instrumentos Quirúrgicos,
Herida Quirúrgica/patología,
Herida Quirúrgica/fisiopatología,
Análisis de Matrices Tisulares,
Procedimientos Quirúrgicos Ultrasónicos,
Cicatrización de Heridas/fisiología
Abstract Purpose: To evaluate a novel and adapted low-cost set model for laparoscopic surgery in rats. Methods: Nine Wistar rats underwent two different laparoscopic procedures, splenectomy (n=3) and distal pancreatectomy with splenectomy (n = 6), after assembling a low-cost set replacing the conventio...
Costos y Análisis de Costo,
Laparoscopía/economía,
Laparoscopía/educación,
Laparoscopía/métodos,
Modelos Animales,
Pancreatectomía/economía,
Pancreatectomía/educación,
Pancreatectomía/métodos,
Ratas Wistar,
Esplenectomía/economía,
Esplenectomía/educación,
Esplenectomía/métodos
Abstract Purpose: To evaluate if Moringa oleifera leaf aqueous extract (ME) influences the healing of skin wounds of diabetic rats. Methods: Wistar rats were used (6 rats/group). Group 1 received normal saline (NS) v.o. Group 2 received moringa extract (100mg/kg v.o) for 3 weeks. Groups 3 and 4: Stre...
Abstract Purpose: To evaluate the effects of hyperbaric oxygenation on prevention of adhesions in the abdominal cavity after laparotomy. Methods: Fifty four rats underwent laparotomy; stitches were made in the four quadrant parietal peritoneum and abdominal cavity closure. Animals were divided into th...
Abstract Purpose: To analyze the therapeutic potentials of different hydroxyapatites used for the correction of bone defects in rats. Methods: Forty rats, male, albino wistar, were distributed in 4 groups. They were submitted to a 3.5 mm defect in tibia. They received low purity hydroxyapatite, Stron...
Abstract Purpose: To evaluate the effects of oxidative stress in pregnant rats submitted to acute and chronic stress, relating to alterations in the uterus, placenta and fetus. Methods: Twenty-four female Wistar albino (Rattus norvegicus), were divided into four groups, for induction of oxidative str...
Enfermedad Aguda,
Glucemia/análisis,
Enfermedad Crónica,
Modelos Animales de Enfermedad,
Peso Fetal/fisiología,
Feto/fisiopatología,
Peroxidación de Lípido/fisiología,
Estrés Oxidativo/fisiología,
Placenta/fisiopatología,
Ratas Wistar,
Estrés Fisiológico/fisiología,
Útero/fisiopatología
Abstract Background In this study, we aimed to investigate the effect of dexmedetomidine on colistin nephrotoxicity in rats. Methods Thirty-two Wistar albino rats were allocated into four groups. Intraperitoneal (ip) saline at 1 mL.kg-1 was administered to the control group and 10 mg.kg-1 ip colistin w...
