Results: 153

Contact lens-related bilateral and simultaneous Acremonium keratitis

Rev. bras. oftalmol; 76 (4), 2017
Abstract This is a case of bilateral and simultaneous Acremonium keratitis related to intermittent and alternating eye soft contact lens use, which has a delayed diagnose, presented amphotericin B resistance with persistent hypopyon and had a positive response to topical natamycin. Besides the unusual pr...

The direct costs of treating human visceral leishmaniasis in Brazil

Abstract INTRODUCTION: The drugs available for visceral leishmaniasis (VL) treatment in Brazil have specific characteristics in terms of operability, effectiveness, toxicity, and cost. The aim of this study was to estimate the direct costs of therapies recommended by the Ministry of Health (MH) for VL t...

Cryptococcal cerebellitis in no-VIH patient

Colomb. med; 48 (2), 2017
Abstract Introduction: Cryptococcosis is an opportunistic fungal infection whose etiology is Cryptococcus neofromans / C. gattii, complex which affects immunocompromised patients mainly. Meningeal infection is one of the most common presentations, but cerebellar affection is rare. Case Description: M...

Minimal inhibitory concentration distributions and epidemiological cutoff values of five antifungal agents against Sporothrix brasiliensis

Mem. Inst. Oswaldo Cruz; 112 (5), 2017
BACKGROUND Sporothrix brasiliensis is the most virulent sporotrichosis agent. This species usually responds to antifungal drugs, but therapeutic failure can occur in some patients. Antifungal susceptibility tests have been performed on this species, but no clinical breakpoints (CBPs) are available. In th...

Eficacia y seguridad de las formulaciones lipídicas de amfotericina B para el tratamiento de primera línea de pacientes adultos con diagnóstico de mucormicosis

INTRODUCCIÓN: Antecedentes: El presente dictamen expone la evaluación de tecnología de la eficacia y seguridad de las formulaciones lipídicas de amfotericina B para el tratamiento de primera líena de pacientes con diagnóstico de mucormicosis. Aspectos Generales: La mucormicosis es una infección ca...

Efficacy and safety of amphotericin B deoxycholate versus N-methylglucamine antimoniate in pediatric visceral leishmaniasis: an open-label, randomized, and controlled pilot trial in Brazil

ABSTRACT INTRODUCTION Despite their high toxicity, antimonials and amphotericin B deoxycholate are commonly used for treating visceral leishmaniasis (VL). Few studies showing conflictive data about their efficacy and adverse events in pediatric population are available. This study aimed to evaluate eff...

Achievement of constitutive fluorescent pLEXSY-egfp Leishmania braziliensis and its application as an alternative method for drug screening in vitro

Mem. Inst. Oswaldo Cruz; 112 (2), 2017
BACKGROUND Gene reporter-fluorescent cells have emerged as alternative method for drug screening. OBJECTIVE Achievement of constitutive expression of fluorescent protein GFP by Leishmania braziliensis as alternative method for drug screening. METHODS L. braziliensis-GFP was generated using Leishmania...

Frequência de Cryptococcus spp. e outras leveduras com potencial patogênico em excretas de aves silvestres em três munícipios do estado de São Paulo

Introdução: Nas últimas décadas, as infeções fúngicas invasivas por leveduras tornou-se um importante problema de saúde pública, dado sua incidência crescente relacionada ao aumento da população suscetível. O reconhecimento destes patógenos em aspectos como, distribuicão ambiental e carate...

Incidência de flebite e flebite pós-infusional em adultos hospitalizados

Rev. gaúch. enferm; 38 (2), 2017
RESUMO Objetivo Avaliar a incidência de flebite durante o uso de cateter intravenoso periférico (CIP) e pós-infusional e analisar a associação com fatores de risco em pacientes hospitalizados. Método Estudo de coorte com 165 pacientes adultos internados em hospital universitário de Porto Alegr...

Quercetin and rutin as potential agents antifungal against Cryptococcus spp

Braz. j. biol; 76 (4), 2016
Abstract Amphotericin B is a fungicidal substance that is treatment of choice for most systemic fungal infections affecting as cryptococcosis the immunocompromised patients. However, severe side effects have limited the utility of this drug. The aim of this study was to evaluate the antifungal effect of ...