Results: 104

Evaluation of the impact that the changes in tuberculosis treatment implemented in Brazil in 2009 have had on disease control in the country

J. bras. pneumol; 43 (6), 2017
ABSTRACT Objective: To analyze the impact that the 2009 changes in tuberculosis treatment in Brazil had on the rates of cure, tuberculosis recurrence, mortality, treatment abandonment, and multidrug-resistant tuberculosis (MDR-TB). Methods: An ordinary least squares regression model was used in order t...

Latent tuberculosis infection screening in juvenile idiopathic arthritis patients preceding anti-TNF therapy in a tuberculosis high-risk country

Rev. bras. reumatol; 57 (5), 2017
Abstract Objectives: To evaluate, in an endemic country, the long-term efficacy of latent tuberculosis infection (LTBI) screening and primary prophylaxis in patients with JIA receiving TNF blockers. Methods: This was a retrospective cohort that included JIA patients eligible to anti-TNF therapy. Patien...

Tuberculosis monoarticular de la muñeca: comunicación de un caso

Rev. chil. infectol; 34 (5), 2017
Resumen La tuberculosis monoarticular aislada de la muñeca es una forma infrecuente de presentación de esta enfermedad, siendo más común el compromiso vertebral. Las formas extravertebrales representan sólo 2 a 3% de las infecciones óseas por Mycobacterium tuberculosis. Presentamos el caso clínico...

A prospective study on tubercular fistula in ano and its management

Abstract Objective Tuberculosis fistula in ano, though less encountered, is an important clinical entity in developing countries like India. Diagnosis of TB fistula is a challenge despite of advances in diagnostic modalities and it depends upon both local and systemic clinical presentation. This prospec...

Infecção latente por tuberculose entre pessoas com HIV/AIDS, fatores associados e progressão para doença ativa em município no Sul do Brasil

Resumo: Propôs-se levantar a prevalência de infecção latente por tuberculose (ILTB) entre pessoas vivendo com HIV/AIDS (PVHA), fatores associados e se entre os casos identificados houve progressão para tuberculose ativa. Trata-se de estudo epidemiológico e descritivo. A população foi composta de ...

Efficacy and safety of a four-drug fixed-dose combination regimen versus separate drugs for treatment of pulmonary tuberculosis: a systematic review and meta-analysis

Braz. j. microbiol; 48 (2), 2017
Abstract Introduction: Tuberculosis, particularly multi-drug-resistant tuberculosis, is a major cause of morbidity and mortality worldwide. To the best of our knowledge, however, no study to date has assessed the combined use of the four available drugs for tuberculosis treatment, which is an issue of g...

Treatment of latent tuberculosis in patients with juvenile rheumatic diseases: a systematic review

Rev. bras. reumatol; 57 (3), 2017
ABSTRACT Introduction: Children and adolescents with rheumatic diseases receiving TNF blockers are at risk for the activation of latent Mycobacterium tuberculosis infection (LTBI). Although LTBI treatment is indicated in this group, there are different therapeutic regimens in the literature, without a d...

Tratamiento de meningitis tuberculosa en paciente HIV negativo, posible reacción paradojal
Possible paradoxical reaction to treatment of tubercular meningitis in an HIV negative patient

Medicina (B.Aires); 77 (2), 2017
La respuesta paradojal al tratamiento tuberculoso es la aparición de manifestaciones clínico-radiológicas nuevas, o el empeoramiento de las previas, luego de una mejoría inicial con el tratamiento específico. Se puede observar en 6-30% de los casos de tuberculosis meníngea. Es una reacción inmunol...

Clinical and epidemiological characteristics associated with unfavorable tuberculosis treatment outcomes in TB-HIV co-infected patients in Brazil: a hierarchical polytomous analysis

Braz. j. infect. dis; 21 (2), 2017
Abstract Background: TB patients co-infected with HIV have worse treatment outcomes than non-coinfected patients. How clinical characteristics of TB and socioeconomic characteristics influence these outcomes is poorly understood. Here, we use polytomous regression analysis to identify clinical and epide...

Avances en el tratamiento de la tuberculosis multirresistente

Resumen El tratamiento de las tuberculosis multidrogorresistentes (TBC-MDR) se basa en esquemas de fármacos con diseños muy variables, en pacientes con patrones de resistencia heterogéneos y seguimientos no estandarizados, lo que hace dificil plantear recomendaciones con fuerte nivel de evidencia. Ade...