Abstract: Pemphigus vulgaris is a chronic autoimmune bullous dermatosis that results from the production of autoantibodies against desmogleins 1 and 3. It is the most frequent and most severe form of pemphigus, occurring universally, usually between 40 and 60 years of age. It usually begins with blisters...
Autoanticuerpos/inmunología,
Desmosomas/inmunología,
Diagnóstico Diferencial,
Inmunoglobulinas Intravenosas/uso terapéutico,
Inmunosupresores/clasificación,
Inmunosupresores/uso terapéutico,
Inmunoterapia/métodos,
Pénfigo/clasificación,
Pénfigo/diagnóstico,
Pénfigo/epidemiología,
Pénfigo/terapia,
Piel/patología,
Encuestas y Cuestionarios
Acquired hemophilia A (AHA) is a rare and life-threatening autoimmune hemorrhagic disorder where autoantibodies are developed against factor VIII. An early diagnosis is challenging and mandatory: an immediate hemostatic control is required to reduce morbidity and mortality. Laboratory features of AHA are...
Goodpasture Syndrome is described as a single episode disease entity. It is diagnosed with the demonstration of antiglomerular basement (anti-GBM) antibodies in plasma or renal tissue. Although the recurrence of anti-GBM disease is rare, it has been reported in up to 3% of cases. Recurrence with negative...
Enfermedad por Anticuerpos Antimembrana Basal Glomerular/patología,
Autoanticuerpos/análisis,
Antibacterianos/uso terapéutico,
Enfermedad por Anticuerpos Antimembrana Basal Glomerular/diagnóstico por imagen,
Enfermedad por Anticuerpos Antimembrana Basal Glomerular/tratamiento farmacológico,
Biopsia,
Ciclofosfamida/uso terapéutico,
Técnica del Anticuerpo Fluorescente,
Enfermedades Renales/patología,
Glomérulos Renales/patología,
Prednisona/uso terapéutico,
Recurrencia,
Combinación Trimetoprim y Sulfametoxazol/uso terapéutico
Palomino-Lescano, Henry;
Segura-Chávez, Darwin;
Quispe-Orozco, Darko;
Castro-Suarez, Sheila;
De la Cruz, Walter;
Zapata-Luyo, Willy;
Delgado-Ríos, José;
Cam, Juan;
Alvarado-Morales, Marcela;
Paredes-Carcasi, Lippmann;
Cornejo-Herrera, Iván;
Meza-Vega, María.
RESUMEN La encefalitis autoinmune por anticuerpos contra el receptor N-metil-D-aspartato (anti-NMDAR) es un desorden mediado por anticuerpos contra antígenos de superficie neuronal, cuyo diagnóstico temprano y tratamiento oportuno mejoran el pronóstico de la enfermedad. Se presentan cuatro casos con e...
ABSTRACT Introduction: Psoriasis is a chronic disease associated with multiple comorbidities including inflammatory intestinal disease. There are no previous studies in Colombia regarding the relationship of gastrointestinal symptoms in patients with psoriasis. Objective: To determine the frequency o...
Resumen El lupus eritematoso generalizado (LEG) es una enfermedad autoinmune crónica caracterizada por la pérdida de la tolerancia a los antígenos propios y la síntesis de diferentes autoanticuerpos con la formación y depósito de complejos inmunes y el daño de múltiples órganos. Las células T r...
Abstract Rheumatoid arthritis (RA) is an autoimmune/inflammatory disease affecting 0.5 to 1% of adults worldwide and frequently leads to joint destruction and disability. Early diagnosis and early and effective therapy may prevent joint damage and lead to better long-term results. Therefore, reliable bio...
Abstract Background/objective: Digital ulcers (DUs) represent a frequent complication of systemic sclerosis (SSc). The aim of this study was to evaluate clinical, serological and capillaroscopy features that are associated with DUs in patients with SSc. Methods: In this bicentric cross-sectional study,...
Cruvinel, Wilson de Melo;
Andrade, Luis Eduardo Coelho;
von Mühlen, Carlos Alberto;
Dellavance, Alessandra;
Ximenes, Antônio Carlos;
Bichara, Carlos David;
Bueno, Cleonice;
Mangueira, Cristóvão Luis Pitangueira;
Bonfá, Eloísa;
Brito, Fabiano de Almeida;
Flumian, Fernanda Bull;
Silva, Glaucielen Gomes da;
Rêgo, Jozelia;
Anjos, Lisiane Maria Ericoni dos;
Slhessarenko, Natasha;
Pasoto, Sandra Gofinet;
Neves, Suzane Pretti Figueiredo;
Valim, Valéria;
Santos, Wilton Silva dos;
Francescantonio, Paulo Luiz Carvalho.
Abstract Background: The V Brazilian Consensus for determination of autoantibodies against cellular constituents on HEp-2 cells, held in Brasilia (DF, Brazil) on August 27, 2016, discussed the harmonization between the Brazilian Consensus on ANA (BCA) guidelines and the International Consensus on ANA Pa...
Abstract Background: To analyze the frequency and clinical relevance of anti-Mi-2 autoantibody in a representative sample of patients with dermatomyositis. Methods: This longitudinal inception cohort study, from 2001 to 2017, included 87 definite adult dermatomyositis. Anti-Mi-2 analysis was performed ...
