Acute kidney injury
Rev. Assoc. Med. Bras. (1992, Impr.); 66 (supl.1), 2020
Results: 172
Effect of testosterone on proliferation markers and apoptosis in breasts of ovariectomized rats
Rev. bras. ginecol. obstet; 41 (12), 2019
Abstract Objective To investigate the action of testosterone (T), isolated or associated with estradiol benzoate (EB), on the proliferation markers and apoptosis of breasts of ovariectomized rats. Methods A total of 48 castrated female Wistar rats were divided into 6 groups, and each of them were sub...
Apoptosis/efectos de los fármacos, Biomarcadores/análisis, Mama/citología, Mama/patología, Calcinosis/patología, Caspasa 3/análisis, Proliferación Celular/efectos de los fármacos, Estradiol/análogos & derivados, Estradiol/farmacología, Ovariectomía, Antígeno Nuclear de Célula en Proliferación/análisis, Ratas Wistar, Testosterona/farmacología
Zinc alpha 2 glycoprotein as an early biomarker of diabetic nephropathy in patients with type 2 diabetes mellitus
J. bras. nefrol; 41 (4), 2019
Abstract Introduction: Although microalbuminuria remains the gold standard for early detection of diabetic nephropathy (DN), it is not a sufficiently accurate predictor of DN risk. Thus, new biomarkers that would help to predict DN risk earlier and possibly prevent the occurrence of end-stage kidney dis...
Albuminuria/orina, Biomarcadores/análisis, Estudios de Casos y Controles, Creatinina/sangre, Diabetes Mellitus Tipo 2/complicaciones, Diabetes Mellitus Tipo 2/orina, Nefropatías Diabéticas/sangre, Nefropatías Diabéticas/fisiopatología, Nefropatías Diabéticas/orina, Diagnóstico Precoz, Tasa de Filtración Glomerular/fisiología, Fallo Renal Crónico/prevención & control, Valor Predictivo de las Pruebas, Medición de Riesgo, Proteínas de Plasma Seminal/análisis, Sensibilidad y Especificidad
Thalidomide reduces cell proliferation in endometriosis experimentally induced in rats
Rev. bras. ginecol. obstet; 41 (11), 2019
Abstract Objective To analyze the effect of thalidomide on the progression of endometriotic lesions experimentally induced in rats and to characterize the pattern of cell proliferation by immunohistochemical Proliferating Cell Nuclear Antigen (PCNA) labeling of eutopic and ectopic endometrium. Methods...
Inhibidores de la Angiogénesis/farmacología, Biomarcadores/análisis, Proliferación Celular/efectos de los fármacos, Modelos Animales de Enfermedad, Relación Dosis-Respuesta a Droga, Endometriosis/patología, Endometrio/patología, Antígeno Nuclear de Célula en Proliferación/análisis, Ratas Wistar, Talidomida/farmacología
Waist-to-height ratio is as reliable as biochemical markers to discriminate pediatric insulin resistance
J. pediatr. (Rio J.); 95 (4), 2019
Abstract Objective: Given the importance of incorporating simple and low-cost tools into the pediatric clinical setting to provide screening for insulin resistance, the present study sought to investigate whether waist-to-height ratio is comparable to biochemical markers for the discrimination of insuli...
Biomarcadores/análisis, Glucemia/análisis, Índice de Masa Corporal, Brasil, HDL-Colesterol/sangre, Estudios Transversales, Resistencia a la Insulina/fisiología, Lipoproteínas HDL/sangre, Síndrome Metabólico/sangre, Síndrome Metabólico/fisiopatología, Sobrepeso/sangre, Sobrepeso/fisiopatología, Triglicéridos/sangre, Circunferencia de la Cintura/fisiología, Relación Cintura-Estatura
Chloride and sodium ion concentrations in saliva and sweat as a method to diagnose cystic fibrosis
J. pediatr. (Rio J.); 95 (4), 2019
Abstract Objective: Cystic fibrosis diagnosis is dependent on the chloride ion concentration in the sweat test (≥ 60 mEq/mL - recognized as the gold standard indicator for cystic fibrosis diagnosis). Moreover, the salivary glands express the CFTR protein in the same manner as sweat glands. Given t...
Biomarcadores/análisis, Estudios de Casos y Controles, Cloruros/análisis, Fibrosis Quística/diagnóstico, Fibrosis Quística/genética, Regulador de Conductancia de Transmembrana de Fibrosis Quística/análisis, Regulador de Conductancia de Transmembrana de Fibrosis Quística/genética, Genotipo, Saliva/química, Sodio/química, Sodio/metabolismo, Sudor/química
Utilidad de la determinación de anticuerpos en el diagnóstico de las enfermedades reumáticas
Usefulness of the determination of antibodies in the diagnosis of rheumatic diseases
Rev. cuba. reumatol; 21 (2), 2019
Introducción: las enfermedades reumáticas son consideradas como una de las principales causas de discapacidad y de disminución de la percepción de calidad de vida relacionada con la salud. El daño articular y sistémico que producen conduce a un deterioro progresivo y crónico del cuerpo humano, de...
Acute kidney injury after cardiac surgery: risk factors and novel biomarkers
Rev. bras. cir. cardiovasc; 34 (3), 2019
Abstract Acute kidney injury (AKI) is a common and severe complication after cardiac surgery. Currently, a series of novel biomarkers have favored the assessment of AKI after cardiac surgery in addition to the conventional indicators. The biomartkers, such as urinary liver fatty acid binding protein (L-F...
Micro RNA 146a-5p expression in Kidney transplant recipients with delayed graft function
J. bras. nefrol; 41 (2), 2019
ABSTRACT Introduction: The development of novel non-invasive biomarkers of kidney graft dysfunction, especially in the course of the delayed graft function period would be an important step forward in the clinical practice of kidney transplantation. Methods: We evaluated by RT-PCR the expression of miR...
Área Bajo la Curva, Biomarcadores/análisis, Biopsia, Funcionamiento Retardado del Injerto/genética, Funcionamiento Retardado del Injerto/patología, Rechazo de Injerto/genética, Trasplante de Riñón, MicroARNs/análisis, MicroARNs/genética, Curva ROC, Daño por Reperfusión/genética, Reacción en Cadena de la Polimerasa de Transcriptasa Inversa
The expression of and preoperative correlation between heat-shock protein 70, euroscore, and lactate in patients undergoing cabg with cardiopulmonary bypass
Rev. bras. cir. cardiovasc; 34 (2), 2019
Abstract Objetive: Coronary artery bypass grafting (CABG) with cardiopulmonary bypass (CPB) improved symptoms and increased survival and quality of life in patients with coronary artery disease. However, it should be the main cause of a complex organic systemic inflammatory response that greatly contrib...
Biomarcadores/análisis, Western Blotting, Puente Cardiopulmonar/métodos, Puente Cardiopulmonar/mortalidad, Puente de Arteria Coronaria/métodos, Puente de Arteria Coronaria/mortalidad, Proteínas HSP70 de Choque Térmico/análisis, Ácido Láctico/sangre, Modelos Logísticos, Miocardio/patología, Complicaciones Posoperatorias/etiología, Periodo Preoperatorio, Medición de Riesgo/métodos, Sensibilidad y Especificidad, Estadísticas no Paramétricas