Introducción. Entre las mujeres, el cáncer de mama es el más frecuente
en el mundo. Representa una enfermedad heterogénea, debido a que un mismo
tipo histopatológico puede tener comportamiento biológico distinto según su clasificación
molecular, aportando valor pronóstico y como predictor de la ...
Introduction: The relationship between the tumor inflammatory infiltrate, also known as tumor-infiltrating lymphocytes (TILs),
and invasive breast carcinomas has been extensively studied in recent years to verify its association with prognosis and response
to treatment. The goal of this study was to as...
Introduction: Low-grade fibromyxoid sarcoma (LGFMS) is a rare special subtype of fibrosarcoma, it is more common in the trunk and proximal limbs. First described by Evans in 1987, this tumor is also named Evans tumor. Diagnosis of LGFMS may be quite challenging, either due to the low suspicion rate of th...
Purpose: Our aim was to investigate protective effects of daidzein treatment on ischemia-reperfusion (I/R) injury-induced ovarian tissue by immunohistochemical techniques. Methods: Thirty Sprague Dawley female rats were categorized into three groups as sham, I/R group, and I/R+daidzein groups. Bloods we...
Abstract Objective Breast cancer (BC) biomarkers, such as hormone receptors expression, are crucial to guide therapy in BC patients. Antiandrogens have been studied in BC; however, limited data are available on androgen receptor (AR) expression test methodology. We aim to report the core needle biopsy (...
Abstract Objective To investigate the clinicopathological significance and prognosis of the expression of the anterior gradient 3 (AGR3) protein in women with breast cancer. Data Sources The PubMed, CINAHL, EMBASE, Scopus, and Web of Science databases were searched for studies published in English and ...
ABSTRACT Objective: To assess the proliferation of epithelium (using the Ki67 index) and the polarization pattern of collagen in selected odontogenic cysts and tumours. In addition, an exploratory analysis of the effect of inflammation on the proliferation rate was done. Material and Methods: Following...
ABSTRACT Objective: To identify the clinicopathological correlation of E-cadherin expression in metastatic and non-metastatic oral squamous cell carcinoma (OSCC). Material and Methods: A total of 90 paraffin-embedded tissue sections of OSCC were retrieved from the registry. The total selected samples w...
Após a transcrição, as moléculas de RNA podem ser alteradas por uma infinidade de modificações químicas distintas que ocorrem de maneira dinâmica, constituindo o epitranscriptoma. A primeira modificação de mRNA identificada foi a N6-metiladenosina (m6A), afetando quase todas as etapas do metabo...
INTRODUÇÃO: O câncer de bexiga é a 10a neoplasia maligna mais comum no mundo. O tipo músculo-invasivo tem como tratamento padrão-ouro combinações de quimioterapia e cirurgia. Muitos pacientes, no entanto, não respondem a quimioterapia e são submetidos a uma terapia ineficaz. Identificar quais p...
