LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud | LILACS

Results: 838

Avaliação da resposta de anticorpos IgG contra diferentes variantes alélicas do Antígeno 1 de Membrana Apical (AMA-1) de Plasmodium vivax em indivíduos de áreas endêmicas de malária

O Plasmodium vivax é a espécie com maior distribuição geográfica no mundo e a que predomina nas Américas, incluindo o Brasil. Comparado ao Plasmodium falciparum, poucas vacinas contra o P. vivax encontram-se em fase de testes clínicos. Um dos antígenos de formas sanguíneas de P. vivax candidato ...

Caracterização da resposta imune celular e humoral frente ao antígeno protetor rico em cisteína de p. Vivax (pvcyrpa) em indivíduos da Amazônia brasileira

As infecções causadas por Plasmodium vivax representam um grave problema de saúde pública, sendo esta espécie plasmodial considerada uma das mais difíceis de se eliminar. Por esta razão a pesquisa de antígenos candidatos vacinais específicos para P. vivax necessita de impulso, uma vez que atualm...

The socio-environmental production of malaria in three municipalities in the Carajás region, Pará, Brazil

ABSTRACT OBJECTIVE To analyze the environmental production of malaria in the municipalities of Marabá, Parauapebas, and Canaã dos Carajás, in Pará, from 2014 to 2018. METHODS This ecological, cross-sectional study used epidemiological data in the Sistema de Informações de Vigilância EpidemiolÃ...

Dehydrobufotenin extracted from the Amazonian toad Rhinella marina (Anura: Bufonidae) as a prototype molecule for the development of antiplasmodial drugs

he resistance against antimalarial drugs represents a global challenge in the fight and control of malaria. The Brazilian biodiversity can be an important tool for research and development of new medicinal products. In this context, toxinology is a multidisciplinary approach on the development of new dru...

Flight tone characterisation of the South American malaria vector Anopheles darlingi (Diptera: Culicidae)

Mem. Inst. Oswaldo Cruz; 116 (), 2021
BACKGROUND Flight tones play important roles in mosquito reproduction. Several mosquito species utilise flight tones for mate localisation and attraction. Typically, the female wingbeat frequency (WBF) is lower than males, and stereotypic acoustic behaviors are instrumental for successful copulation. Mo...

Malaria mortality in Colombia from 2009 to 2018: a descriptive study

Abstract INTRODUCTION: Colombia has an endemo-epidemic for malaria, with a downward trend in mortality over the last few decades. This study describes the malaria mortality rates from 2009-2018. METHODS We obtained data from the Colombian Mortality Information System and calculated the case fatality a...

Electrocardiographic effect of artemisinin-piperaquine, dihydroartemisinin-piperaquine, and artemether-lumefantrine treatment in falciparum malaria patients

Abstract INTRODUCTION: Artemisinin-based combination therapy (ACT), such as artemisinin-piperaquine (AP), dihydroartemisinin-piperaquine (DP), and artemether-lumefantrine (AL), is the first-line treatment for malaria in many malaria-endemic areas. However, we lack a detailed evaluation of the cardiotox...

Avaliação de modelos de predição para ocorrência de malária no estado do Amapá, 1997-2016: um estudo ecológico

Objetivo: Avaliar a capacidade preditiva de diferentes modelos de série temporal de casos de malária no estado do Amapá, Brasil, no período 1997-2016. Métodos: Estudo ecológico de séries temporais com casos de malária registrados no Amapá. Foram utilizados dez modelos estatísticos determinís...

Quinolinotriazole antiplasmodials via click chemistry: synthesis and in vitro studies of 7-Chloroquinoline-based compounds

Malaria is nowadays one of the most serious health concerns in a global scale and, although there is an evident increase in research studies in this area, pointed by the vast number of hits and leads, it still appears as a recurrent topic every year due to the drug resistance shown by the parasite exposi...

Enfermedades Transmitidas por Vectores (ETV). Gestión del programa en Bogotá 2017 a 2021

Introducción: las Enfermedades Transmitidas por Vectores (ETV) representan más del 17 % de las enfermedades infecciosas, provocan cada año 700.000 muertes a nivel mundial según la Organización Mundial de la Salud (OMS); el programa de ETV en Bogotá integra la Gestión de Programas y Acciones de Int...