Diabetes mellitus is a metabolic disorder characterized by the presence of chronic hyper-glycemia that is accompanied, to a greater or lesser extent, by alterations in the metabolism of carbohydrates, proteins and lipids. It is the leading cause of death in develope...
Sugauara, Rosângela Rumi;
Bortolucci, Wanessa de Campos;
Fernandez, Carla Maria Mariano;
Cabral, Márcia Regina Pereira;
Gonçalves, Regina Aparecida Correia;
Sarragiotto, Maria Helena;
Gonçalves, José Eduardo;
Colauto, Nelson Barros;
Linde, Giani Andrea;
Nunes, Maria Graciela Iecher Faria;
Ruiz, Suelen Pereira;
Gazim, Zilda Cristiani.
Campomanesia xanthocarpa leaves are a byproduct of fruit production without studies on antioxidant activity. Thus, this study aimed to identify the antioxidant compounds of C. xanthocarpaleaves by ultra-high performance liquid chromatography coupled with electrospray...
Myrtaceae/química,
Antioxidantes/farmacología,
Plantas Medicinales,
Extractos Vegetales/química,
Extractos Vegetales/farmacología,
Antioxidantes/química,
Cromatografía Líquida de Alta Presión,
Espectrometría de Masa por Ionización de Electrospray,
Hojas de la Planta/química,
Hidroxibenzoatos/análisis,
Ácido Clorogénico/análisis,
Ácido Quínico/análisis,
Quercetina/análisis
Cancer is an important disease that causing to deaths in the world. Cervical cancer is one of the most common among women and must be treated quickly to prevent cell proliferation. Natural products have been used for cancer treatment due to their antiproliferative and apoptosis induction pro...
Inula/química,
Apoptosis/efectos de los fármacos,
Antineoplásicos Fitogénicos/uso terapéutico,
Neoplasias del Cuello Uterino/tratamiento farmacológico,
Plantas Medicinales,
Antineoplásicos Fitogénicos/farmacología,
Antineoplásicos Fitogénicos/química,
Extractos Vegetales/uso terapéutico,
Extractos Vegetales/farmacología,
Extractos Vegetales/química,
Proliferación Celular/efectos de los fármacos,
Especies Reactivas de Oxígeno,
Espectrometría de Masas en Tándem,
Células HeLa/efectos de los fármacos,
Interleucina-6/análisis,
Interleucina-8/análisis,
Metanol,
Antioxidantes,
Flavonoides/análisis,
Cromatografía Líquida de Alta Presión
The interaction potential of Cynara scolymus L., Mikania glomerata Spreng.,Rhamnus purshiana DC and Uncaria tomentosa (Willd. Ex Roem. & Schult.) with conventional drugs metabolized by the CYP3A4 metabolic route was tested in HeLa cell lines, using the in vitro model of the hPXR. The herbal medicin...
Interacciones de Hierba-Droga,
Cynara scolymus,
Mikania,
Rhamnus,
Uña de Gato,
Técnicas In Vitro,
Citocromo P-450 CYP3A/metabolismo,
Plantas Medicinales,
Receptor X de Pregnano/metabolismo,
Extractos Vegetales/farmacocinética,
Interacciones Farmacológicas
Hedeoma multiflora Benth. (Lamiaceae) is an aromatic-medicinal species native to Argentina, Uruguay and southern Brazil that is in a state of vulnerability due to overexploitation. It is used in the preparation of flavored yerba mate and in popular medicine, mainly in abdomina...
Clausena excavata is a famous folklore medicinal plant in Asian region that is being used for the treatment of different disorders. This study investigated the cytotoxic effects of leaf extracts via MTT assay, as well as the in vitro apoptotic activities of the ethyl acetate C. excavata leaf extract (E...
Linfoma de Burkitt/tratamiento farmacológico,
Clausena/química,
Apoptosis/efectos de los fármacos,
Línea Celular Tumoral/efectos de los fármacos,
Extractos Vegetales/uso terapéutico,
Plantas Medicinales,
Extractos Vegetales/química,
Extractos Vegetales/farmacología,
Acetatos,
Supervivencia Celular/efectos de los fármacos,
Reacción en Cadena de la Polimerasa,
Expresión Génica,
Anexina A5,
Proteína X Asociada a bcl-2,
Apoptosis/genética,
Fitoquímicos/análisis,
Concentración 50 Inhibidora,
Fluoresceína-5-Isotiocianato
Vegetable extracts have become important raw materials for food, pharmaceutical and cosmetic industries because of their biological potential. The objective of this study was to assess the biological activity of vegetable oils (VOs) extracted from Annona muricata...
Annona/química,
Aceites de Plantas/farmacología,
Aceites de Plantas/química,
Antibacterianos/farmacología,
Plantas Medicinales,
Antibacterianos/química,
Semillas,
Bacterias/efectos de los fármacos,
Fitosteroles/análisis,
Cromatografía de Gases y Espectrometría de Masas,
Pruebas de Sensibilidad Microbiana,
Eritrocitos/efectos de los fármacos,
Metaloproteinasa 9 de la Matriz,
Neutrófilos/enzimología
Introducción: Las enfermedades a menudo constituyen alteraciones fisiológicas que requieren acciones inminentes según su gravedad, ante ello, las mujeres andinas ponen en práctica sus conocimientos y actitudes ancestrales a fin de resolverlas, por ser el medio más inmediato. Objetivo: Interpretar la...
Objectives: Medicinal plants and herbal medicines are widely used worldwide. However, patients with chronic health conditions or their caregivers do not often disclose these practices to their healthcare providers, leading to potentially severe interactions with current treatments, especial...
Objetivo: Avaliar a produção científica acerca da utilização de plantas medicinais por idosos e seus conhecimentos sobre riscos e benefícios. Método: estudo descritivo, exploratório com abordagem qualitativa do tipo revisão integrativa da literatura. Os dados foram coletados em julho de 2015, at...
