Abstract: This review does not aim to be an up-to-date of proteomics in Mexico; it simply tries to trace its development, exposing the story of the researchers, laboratories and some institutions that have contributed to the establishment and development of this science in Mexico....
Abstract: In recent years, the use of high-throughput omics technologies has led to the rapid discovery of many candidate biomarkers. However, few of them have made the transition to the clinic. In this review, the promise of omics technologies to contribute to the process of biomarker development is des...
Abstract: Acute lymphoblastic leukemia (ALL) affects the quality of life of many children in the world and particularly in Mexico, where a high incidence has been reported. With a proper financial investment and with well-organized institutions caring for those patients, together with solid platforms to ...
Background: Jatropha curcas is a wide-spreading latex-rich biodiesel plant with high oil content in seeds that have always been under intense studies. However, studies are lacking on the latex component that is considered rich in proteins with potentially important physiological functions and secondary m...
Jatropha,
Tallos de la Planta/química,
Látex/química,
Proteínas de Plantas/análisis,
Proteínas de Plantas/aislamiento & purificación,
Proteómica/métodos,
Fenol/química,
Acetona/química,
Cromatografía Liquida,
Espectrometría de Masas en Tándem,
Espectrometría de Masa por Ionización de Electrospray,
Electroforesis en Gel de Poliacrilamida
Abstract Mastitis adversely affects milk production and in general cows do not regain their full production levels post recovery, leading to considerable economic losses. Moreover the percentage decrease in milk production depends on the specific pathogen that caused the infection and enterobacteria are ...
Enterobacteriaceae/clasificación,
Enterobacteriaceae/metabolismo,
Espectrometría de Masa por Láser de Matriz Asistida de Ionización Desorción,
Bovinos,
Girasa de ADN/genética,
Enterobacteriaceae/aislamiento & purificación,
Genes Bacterianos,
Mastitis Bovina/diagnóstico,
Leche/microbiología,
Fenotipo,
Proteómica/métodos,
Análisis de Secuencia de ADN,
Mastitis Bovina/microbiología
Abstract Staphylococcus spp. play an important role in the etiology of bovine mastitis. Staphylococcus aureus is considered the most relevant species due to the production of virulence factors such as slime, which is required for biofilm formation. This study aimed to evaluate biofilm production and its ...
Antibacterianos/farmacología,
Biopelículas,
Mastitis Bovina/microbiología,
Infecciones Estafilocócicas/microbiología,
Staphylococcus aureus/efectos de los fármacos,
Staphylococcus aureus/fisiología,
Resistencia betalactámica,
Proteínas Bacterianas/genética,
Bovinos,
Estudios de Asociación Genética,
Pruebas de Sensibilidad Microbiana,
Proteoma,
Proteómica/métodos,
Staphylococcus aureus/ultraestructura,
Transactivadores/genética,
Factores de Virulencia/genética
This study aimed to answer the following questions: 1) does whole fluoridated milk protect
more against enamel and dentin erosion than fat-free fluoridated milk? 2) does the protective
effect of fluoridated milk against erosion follow a dose-response relationship? 3) is the
treatment with whole or fat-fr...
Leche/química,
Sustancias Protectoras/química,
Desmineralización Dental/prevención & control,
Fluoruros/química,
Cariostáticos/química,
Dentina/efectos de los fármacos,
Esmalte Dental/efectos de los fármacos,
Factores de Tiempo,
Proteómica,
Proteínas/análisis,
Reproducibilidad de los Resultados
Os leucotrienos (LTs) são mediadores inflamatórios derivados da via 5-
lipoxigenase (5-LO), com contribuição relevante na reabsorção óssea. Neste estudo
investigamos o papel dos LTs na diferenciação osteogênica e o seu impacto na
osteoclatogênese. Assim, foi avaliado o perfil ósseo dos camund...
Leucotrienos/farmacología,
Osteogénesis/efectos de los fármacos,
Osteoblastos/fisiología,
Densidad Ósea,
Proteínas Activadoras de la 5-Lipooxigenasa/análisis,
Osteogénesis/fisiología,
Microtomografía por Rayos X,
Reacción en Cadena en Tiempo Real de la Polimerasa,
Proteómica,
Expresión Génica,
Factores de Tiempo,
Ligando RANK/análisis,
Reproducibilidad de los Resultados,
Osteoblastos/efectos de los fármacos
Fluoride (F) is a potent anti-cariogenic element, but only an appropriate dose is
effective to have therapeutic action, else systemic toxicity may be observed.
Additionally, two factors, amount of F and time of exposure, drive its action.
Surprisingly, the susceptibility to toxic effects of F is genetica...
Hígado/química,
Hígado/efectos de los fármacos,
Fluoruros/farmacología,
Proteómica/métodos,
Proteínas/análisis,
Fluorosis Dental/metabolismo,
Estrés Oxidativo/fisiología,
Fluorosis Dental/genética,
Factores de Tiempo,
Predisposición Genética a la Enfermedad,
Valores de Referencia
As doenças causadas pelo fitopatógeno Xylella fastidiosa, uma bactéria Gram-negativa, devem-se aos seus múltiplos fatores de virulência, tais como formação de biofilme, secreção de enzimas de degradação da parede celular do xilema (CWDE), expressão de proteínas de adesão e produção de ves...
