Results: 260

Trends and predictors of HIV-1 acquired drug resistance in Minas Gerais, Brazil: 2002-2012

Braz. j. infect. dis; 21 (2), 2017
Abstract Several studies show that the prevalence of multidrug-resistant HIV-1 virus is declining over time. A retrospective cohort study was carried out to evaluate the trends of drug resistance in antiretroviral treatment-exposed individuals in a state of a middle-income country, Minas Gerais, southeas...

Classical and alternative macrophages have impaired function during acute and chronic HIV-1 infection

Braz. j. infect. dis; 21 (1), 2017
Abstract Objectives: Three decades after HIV recognition and its association with AIDS development, many advances have emerged – especially related to prevention and treatment. Undoubtedly, the development of Highly Active Antiretroviral Therapy (HAART) dramatically changed the future of the syndr...

Undiagnosed acute HIV infection identified through RNA testing of pooled serum samples obtained during a dengue outbreak in São Paulo, Brazil

Abstract INTRODUCTION: Improving HIV diagnostics and treatment is necessary to end the AIDS epidemic. Pooled plasma can be used to identify patients with acute HIV disease, even before serological tests. During dengue outbreaks, patients having symptoms common to other acute viral diseases might seek me...

Nueva terapia con anticuerpos monoclonales permitiría eliminar el reservorio del virus de la inmunodeficiencia humana (HIV-1)
New therapy with monoclonal antibodies would allow to eliminate the reservoir of human immunodeficiency virus (HIV-1)

Medicina (B.Aires); 77 (1), 2017

La profilaxis pre-exposición reduciría la incidencia de infecciones por HIV en personas con conductas de alto riesgo

Short communication: failures in detecting HTLV-1 and HTLV-2 in patients infected with HIV-1

Changes in retrovirus acquisition/transmission behaviors have been reported in Brazil, with a concerning increase in HIV-1-infected individuals aged 15-39 years. In São Paulo, HIV-1/HTLV-1 and HIV-1/HTLV-2 coinfections have been associated with intravenous drug use and failure to detect HTLV-1/2 (human ...

Sería baja la tasa de transmisión de VIH entre parejas serodiscordantes con tratamiento supresivo
HIV transmission rate in serodiscordant couples would be low with suppressive treatment

Selective intra-dinucleotide interactions and periodicities of bases separated by K sites: a new vision and tool for phylogeny analyses

Biol. Res; 50 (), 2017
Direct tests of the random or non-random distribution of nucleotides on genomes have been devised to test the hypothesis of neutral, nearly-neutral or selective evolution. These tests are based on the direct base distribution and are independent of the functional (coding or non-coding) or structural (rep...

Resistencia de HIV-1 a drogas antirretrovirales en gestantes del área metropolitana de Buenos Aires
HIV-1 resistance to antiretroviral drugs in pregnant women from Buenos Aires metropolitan area

Medicina (B.Aires); 76 (6), 2016
Se determinó la frecuencia de mutaciones asociadas a resistencia de HIV-1 a antirretrovirales en embarazadas del área metropolitana de Buenos Aires, 2008-2014. Se incluyeron 136 mujeres con carga viral ≥ 500 copias/ml: 77 (56.6%) eran naïve; las otras 59 (43.4%) eran expuestas, ya sea con tratam...