A não união óssea é uma complicação ortopédica que ocorre normalmente devido à instabilidade da fratura em decorrência de uma escolha de fixação inadequada ou inapropriada, suprimento sanguíneo deficiente, osteomielite e afastamento excessivo dos fragmentos; sendo mais comumente em cães de r...
Background: Cell culture (spheroid and 2D monolayer cultures) is an essential tool in drug discovery. Piperlongumine (PLN), a naturally occurring alkaloid present in the long pepper (Piper longum), has been implicated in the regulation of GSTP1 activity. In vitro treatment of cancer cells with PLN increa...
CONTEXTO CLÍNICO: La Enfermedad por el Coronavirus 2019 (COVID–19, por su sigla en inglés Coronavirus Disease 2019) es una enfermedad respiratoria de humanos producida por un nuevo coronavirus identificado con la sigla SARS-CoV-2. El 11 de marzo de 2020 la Organización Mundial de la Salud (OMS) decl...
As of 31 October 2020 This is the tenth edition of this summary of rapid systematic reviews, which includes the results of a rapid systematic review of currently available literature. More than 200 therapeutic options or their combinations are being investigated in more than 1,700 clinical trials. In thi...
Resumen Introducción: El jabón para el aseo cutáneo es de empleo común entre la población, sin embargo, es posible que cause daño a las células de la piel y modifique la barrera cutánea. Objetivo: Determinar el efecto citotóxico de los jabones en queratinocitos cultivados in vitro y correlacio...
Agua Corporal,
Células Cultivadas,
Colorimetría,
Dermatitis Irritante/etiología,
Eritema/inducido químicamente,
Voluntarios Sanos,
Concentración de Iones de Hidrógeno,
Irritantes/efectos adversos,
Queratinocitos/efectos de los fármacos,
Piel/efectos de los fármacos,
Pruebas de Irritación de la Piel,
Jabones/efectos adversos,
Jabones/química
SUMMARY: Residential heating with wood is an important source of ambient air pollution. Evidence links air pollution to serious health effects such as respiratory and cardiovascular mortality and morbidity. We hypothesized that prenatal exposure to wood smoke pollution causes morphological changes in the...
Contaminación del Aire/efectos adversos,
Madera,
Pulmón/efectos de los fármacos,
Pulmón/patología,
Modelos Animales de Enfermedad,
Exposición Materna/efectos adversos,
Humo/efectos adversos,
Feto/efectos de los fármacos,
Análisis de Varianza,
Exposición a Riesgos Ambientales,
Material Particulado/toxicidad,
Calefacción,
Contaminantes Atmosféricos/toxicidad
SUMMARY: The Viperidae venoms are composed of a mixture of constituents with enzymatic and non-enzymatic actions, which act on ultrastructural components of cells and tissues. Here, the number of mitochondria, mitochondrial area and the number of mitochondrial cristae from adrenal glands cortex treated w...
SUMMARY: The aim of this study is to investigate the effects of Protocatechuic acid and Corchorus olitorius on streptozotocin (STZ) induced diabetic rat testis tissue. Randomly selected Wistar Albino rats were divided into five groups as; Diabetes Mellitus, Diabetes Mellitus treated with Corchorus Olitor...
SUMMARY: Studies in humans showed that prenatal exposure to urban air pollution (AP) influences fetal development, and increases the incidence of adverse pregnancy outcomes and some diseases in postnatal life. However, most of these were performed in environments where the main source of environmental pa...
Humo/efectos adversos,
Contaminación Ambiental/efectos adversos,
Contaminantes Atmosféricos/toxicidad,
Exposición Materna/efectos adversos,
Placenta/efectos de los fármacos,
Feto/efectos de los fármacos,
Tamaño Corporal,
Ratas Sprague-Dawley,
32408/efectos adversos,
Desarrollo Fetal/efectos de los fármacos,
Madera,
Material Particulado
SUMMARY: The objective of this study were bone defect complications that occur due to traumas or infections. Bone grafts are required to provide support, fill gaps and improve biological repair in skeletal damage. Dexamethasone plays role in calcium signaling modulation and used in diseases. Aim of this ...
Tibia/cirugía,
Tibia/efectos de los fármacos,
Trasplante Óseo,
Dexametasona/administración & dosificación,
Osteonectina/fisiología,
Osteopontina/fisiología,
Ratas Wistar,
Inmunohistoquímica,
Tibia/patología,
Remodelación Ósea,
Regeneración Ósea,
Modelos Animales de Enfermedad
