Results: 5032

Hepatotoxicity-induced by the therapeutic dose of acetaminophen and the ameliorative effect of oral co-administration of selenium/Tribulus terrestris extract in rats

Int. j. morphol; 38 (5), 2020
SUMMARY: Over dose or long-term clinical use of therapeutic doses of acetaminophen (APAP) causes hepatotoxicity. Various strategies attempted to ameliorate APAP-hepatotoxicity have been found to be unsuitable for clinical practice. This study was aimed to illustrate the histopathological changes induced ...

Effects of melatonin against thioacetamide-induced testicular toxicity in rats

Int. j. morphol; 38 (5), 2020
SUMMARY: This study aimed to investigate the changes in testis tissue of thioacetamide-induced rats and the effect of melatonin on these changes. Thirty-five male Wistar Albino rats were divided into five groups. Group I; Control (n=7), Group II; Melatonin (Mel) (10 mg/kg) a single dose (i.p)(n=7), Group...

Antimicrobial resistance evaluation of bacteria isolated from infections in small animals in the Umuarama region, Paraná

Pesqui. vet. bras; 40 (10), 2020
Bacterial resistance is shown to be an inevitable side effect due to the excessive use of antibiotics, becoming a significant concern worldwide. Knowledge of regional bacterial resistance profiles enables the development of site-specific infection control practices, making conscious and moderate use of c...

Considerations on the use of antihypertensive blockers of the renin-angiotensin system in adults and children in the face of the COVID-19 pandemic

Abstract As severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-infected patients with hypertension and other cardiovascular comorbidities develop more severe coronavirus disease (COVID)-19 and are at high risk of death, a controversy arose about the use of antihypertensives as angiotensin-conve...

Lidocaine in oncological surgery: the role of blocking in voltage-gated sodium channels. A narrative review

Rev. bras. anestesiol; 70 (5), 2020
Abstract Background: The current evidence suggests that oncological surgery, which is a therapy used in the treatment of solid tumors, increases the risk of metastasis. In this regard, a wide range of tumor cells express Voltage-Gated Sodium Channels (VGSC), whose biological roles are not related to the...

Antibioticoterapia empírica en pacientes COVID-19

CONTEXTO CLÍNICO: La Enfermedad por el Coronavirus 2019 (COVID–19, por su sigla en inglés Coronavirus Disease 2019) es una enfermedad respiratoria de humanos producida por un nuevo coronavirus identificado con la sigla SARS-CoV-2. El 11 de marzo de 2020 la Organización Mundial de la Salud (OMS) decl...

Ongoing living update of potential COVID-19 therapeutics: summary of rapid systematic reviews - 22 September 2020

As of 31 October 2020 This is the tenth edition of this summary of rapid systematic reviews, which includes the results of a rapid systematic review of currently available literature. More than 200 therapeutic options or their combinations are being investigated in more than 1,700 clinical trials. In thi...

Posicionamiento de la Red Argentina Pública de Evaluación de Tecnologías Sanitarias sobre el Ibuprofeno inhalatorio para pacientes con COVID-19 al 18 de Septiembre del 2020

INTRODUCCIÓN: La pandemia de COVID-19 causada por un nuevo virus SARS-CoV2, ha desencadenado la búsqueda vertiginosa de alternativas terapéuticas o preventivas que permitan mitigar su impacto. En la carrera contra el virus, en lo que va del año, se han registrado en Argentina 634 presentaciones de es...

Efeito da suplementação com óleo de avocado (Persea americana Mill) na temperatura superficial corpórea de equinos antes e após exercício em esteira

Oito equinos foram distribuídos em delineamento randomizado cruzado, sendo um grupo sem suplementação (GC) e outro grupo suplementado com óleo de avocado (GOAv) por um período de sete semanas. Ao fim da sexta semana, os animais foram submetidos a teste padrão de exercício progressivo (TPEP) e, ap...