ABSTRACT Objective To compare the effects of fermented kefir on the nutritional, physiological, and biochemical parameters of rats. Methods Grains of milk kefir (whole and skimmed) and water kefir (brown sugar) were used. The chemical composition analysis was performed on substrates and fermented bever...
Periodontal disease (PD) has been considered a probable risk factor for several systemic diseases. among them, PD is presumed to be one of the possible etiologies of chronic illness of the central nervous system. In this context, poor oral health and PD is associated with substance abuse in humans. howev...
Abstract Purpose: To evaluate the efficacy of the application of the human amniotic membrane (HAM) on the inflammatory process, fibroblast proliferation, formation of collagenand reduction of skin wound areas in rats. Methods: Thirty six rats were submitted to a surgical injury induction and divided ...
Amnios/química,
Amnios/trasplante,
Apósitos Biológicos,
Colágeno/farmacología,
Colágeno Tipo I/metabolismo,
Colágeno Tipo I/farmacología,
Colágeno Tipo III/metabolismo,
Colágeno Tipo III/farmacología,
Modelos Animales de Enfermedad,
Fibroblastos/metabolismo,
Fibroblastos/patología,
Inflamación/metabolismo,
Distribución Aleatoria,
Ratas Wistar,
Piel/lesiones,
Piel/patología,
Cicatrización de Heridas/efectos de los fármacos,
Cicatrización de Heridas/fisiología
Abstract Purpose: To investigate the effects of pycnogenol on peritoneal adhesions and additionally to investigate the immunohistochemical effects of free oxygen radicals and reactive lymph nodes detected in the adhesive tissue that was sampled surrounding the cecum on intra-abdominal adhesions. Metho...
Antiinflamatorios/uso terapéutico,
Antioxidantes/uso terapéutico,
Modelos Animales de Enfermedad,
Flavonoides/efectos adversos,
Flavonoides/uso terapéutico,
Radicales Libres/análisis,
Inmunohistoquímica,
Inflamación/inducido químicamente,
Inflamación/patología,
Laparotomía,
Ganglios Linfáticos/efectos de los fármacos,
Ganglios Linfáticos/patología,
Estrés Oxidativo/efectos de los fármacos,
Enfermedades Peritoneales/etiología,
Enfermedades Peritoneales/prevención & control,
Peritoneo/patología,
Peritoneo/cirugía,
Extractos Vegetales,
Complicaciones Posoperatorias,
Ratas Wistar,
Especies Reactivas de Oxígeno/metabolismo,
Adherencias Tisulares/etiología,
Adherencias Tisulares/patología,
Adherencias Tisulares/prevención & control
Abstract Purpose: To evaluate the concentration of transforming growth factor beta 1 (TGFB1) levels in a rat pleural effusion obtained by inoculation of intrapleural bacteria or turpentine through thoracentesis. Methods: Thirty-Nine Wistar rats were divided into three groups: Staphylococcus aureus (SA...
Abstract Purpose: To compare polyglactin 910 and simple catgut sutures for the incidence of intraperitoneal adhesions. Methods: Twenty female Wistar rats were placed into two groups. Group 1 received ischemic sutures and Group 2 received polyglactin 910. Five sutures inductive of adhesions in each ra...
Catgut/efectos adversos,
Catgut/tendencias,
Modelos Animales de Enfermedad,
Isquemia/etiología,
Enfermedades Peritoneales/etiología,
Enfermedades Peritoneales/prevención & control,
Peritoneo/irrigación sanguínea,
Peritoneo/cirugía,
Poliglactina 910/efectos adversos,
Poliglactina 910/farmacocinética,
Complicaciones Posoperatorias/etiología,
Ratas Wistar,
Técnicas de Sutura/efectos adversos,
Adherencias Tisulares/etiología,
Adherencias Tisulares/prevención & control
Abstract Purpose: To investigate thymoquinone, curcumin and a combination of these two drugs were effective or not at the growth of liver. Methods: Forty female Wistar-Albino rats distributed into five groups of eight rats each, control, thymoquinone, curcumin, and thymoquinone/curcumin groups. Pathol...
Antineoplásicos/farmacología,
Antioxidantes/farmacología,
Arginasa/sangre,
Benzoquinonas/farmacología,
Biomarcadores/sangre,
Proliferación Celular,
Ceruloplasmina/análisis,
Curcumina/farmacología,
Hepatectomía/métodos,
Antígeno Ki-67/análisis,
Hígado/patología,
Neoplasias Hepáticas/cirugía,
Regeneración Hepática/efectos de los fármacos,
Trasplante de Hígado,
Óxido Nítrico/sangre,
Ratas Wistar,
Activador de Tejido Plasminógeno/sangre
Abstract Purpose: To analyzed the healing effect of the powdered shell of the Megalobulimus lopesi snail on wounds of diabetic rats, since in non-diabetic rats the powdered shell presented healing potential. Methods: Seventy-two Wistar rats (Rattus norvegicus albinus) were divided into three groups: C...
Administración Tópica,
Exoesqueleto/química,
Antiinflamatorios/administración & dosificación,
Antiinflamatorios/farmacología,
Diabetes Mellitus Experimental/fisiopatología,
Modelos Animales de Enfermedad,
Polvos,
Ratas Wistar,
Repitelización,
Caracoles,
Extractos de Tejidos/administración & dosificación,
Extractos de Tejidos/farmacología,
Cicatrización de Heridas/efectos de los fármacos
ABSTRACT Objective: to validate an experimental model for the measurement of glycemic levels in surgical flaps with the use of common glucometers, and to analyze the diagnostic criteria for hypoperfusion of such flaps. Methods: we performed vertical myocutaneous rectus abdominis flaps with upper pedicl...
Silva, Lígia Helena Ferreira Melo E;
Silva, João Marcos DE Meneses E;
Salama, Mahmoud;
Pinheiro, Luiz Gonzaga Porto;
Lunardi, Franciele Osmarini;
Silva, Paulo Goberlânio Barros da;
Hirth, Carlos Gustavo;
Lucena, Igor Freitas de;
Gomes, Glauco Jorge da Costa;
Leite, José Alberto Dias.
ABSTRACT Objectives: to evaluate estradiol levels and autotransplantation heated ovarian tissue effects, after vitrification, on rats bone metabolism previously oophorectomized bilaterally. Methods: experimental study with 27 rats aged 11 to 12 weeks and weighing 200g to 300g, submitted to bilateral oo...
