ABSTRACT Purpose To assess the impact of sperm retrieval on the gonadal function of rats with impaired spermatogenesis by comparing testicular sperm extraction (TESE) to aspiration (TESA). The efficacy of these procedures to sperm obtainment was also compared. Materials and Methods A pilot study showed...
Modelos Animales,
Orquidopexia/métodos,
Proyectos Piloto,
Distribución Aleatoria,
Ratas Wistar,
Motilidad Espermática/fisiología,
Recuperación de la Esperma/efectos adversos,
Espermatogénesis/fisiología,
Espermatozoides/fisiología,
Testículo/fisiología,
Testículo/cirugía,
Testosterona/biosíntesis
Pontes, Henrique Budib Dorsa;
Pontes, José Carlos Dorsa Vieira;
Azevedo Neto, Euler de;
Vendas, Giovanna Serra da Cruz;
Miranda, João Victor Cunha;
Dias, Letícia do Espírito Santos;
Oliva, João Victor Durães Gomes;
Almeida, Murilo Henrique Martins de;
Chaves, Ian de Oliveira;
Sampaio, Tricia Luna;
Santos, Carlos Henrique Marques dos;
Dourado, Doroty Mesquita.
Abstract Introduction: Reperfusion injury leads to systemic morphological and functional pathological alterations. Some techniques are already estabilished to attenuate the damage induced by reperfusion. Ischemic preconditioning is one of the standard procedures. In the last 20 years, several experiment...
ABSTRACT The present study investigated the effects of carvacrol on motor and memory deficits as well as hyperalgesia in the 6-OHDA-lesioned rat model of Parkinson's disease. The animals were subjected to unilateral microinjection of 6-OHDA into the medial forebrain bundle and treated with carvacrol (25,...
Antioxidantes/farmacología,
Antioxidantes/uso terapéutico,
Antiparkinsonianos/farmacología,
Antiparkinsonianos/uso terapéutico,
Cimenos,
Modelos Animales de Enfermedad,
Peroxidación de Lípido/efectos de los fármacos,
Trastornos de la Memoria/tratamiento farmacológico,
Trastornos de la Memoria/fisiopatología,
Memoria a Corto Plazo/efectos de los fármacos,
Monoterpenos/farmacología,
Monoterpenos/uso terapéutico,
Actividad Motora/efectos de los fármacos,
Neuralgia/tratamiento farmacológico,
Neuralgia/fisiopatología,
Oxidopamina,
Enfermedad de Parkinson/tratamiento farmacológico,
Enfermedad de Parkinson/fisiopatología,
Distribución Aleatoria,
Ratas Wistar,
Reproducibilidad de los Resultados,
Compuestos de Sulfhidrilo/análisis
ABSTRACT Objective The goal of this study were to investigate the effects of continuous exercise with/or without the ingestion the Camu-camu pulp in a rat model of obesity. Methods Neonate male Wistar rats, receiving monosodium glutamate, subcutaneously were separated into foour groups: sedentary group...
The aim of this work was to analyse the parasympathetic control of submandibular saliva secretory response to cholinergic and peptidergic agonists in rats chronically exposed to constant light or repeated immobilization. Thirty two adult male Wistar rats were used: LL (8 rats exposed to constant light fo...
Abstract Purpose: To compare the influence of two metallic implants in the diagnosis of periprosthetic infection using 99m technetium-labeled ceftizoxime. Methods: Twenty rats were randomly divided into four groups, which received sterile and contaminated titanium and stainless steel implants. After 3...
Materiales Biocompatibles/química,
Ceftizoxima/análogos & derivados,
Compuestos de Organotecnecio,
Infecciones Relacionadas con Prótesis/diagnóstico por imagen,
Infecciones Relacionadas con Prótesis/microbiología,
Radiactividad,
Cintigrafía,
Radiofármacos,
Distribución Aleatoria,
Ratas Wistar,
Valores de Referencia,
Reproducibilidad de los Resultados,
Acero Inoxidable/química,
Acero Inoxidable/efectos de la radiación,
Factores de Tiempo,
Titanio/química,
Titanio/efectos de la radiación
Summary Objective: Ovarian torsion must be diagnosed and treated as early as possible. The aim of the present study was to investigate the effects of intraperitoneal administration of nanocurcumin on ischemia-reperfusion injury in ovaries. Method: Thirty-five (35) healthy female Wistar rats weighing ap...
Administración Cutánea,
Antioxidantes/administración & dosificación,
Curcumina/administración & dosificación,
Modelos Animales de Enfermedad,
Inyecciones Intraperitoneales,
Isquemia/tratamiento farmacológico,
Isquemia/patología,
Nanopartículas/administración & dosificación,
Ovario/irrigación sanguínea,
Ratas Wistar,
Daño por Reperfusión/tratamiento farmacológico,
Daño por Reperfusión/patología
ABSTRACT In this study, the effect of thymoquinone (TQ) on propylthiouracil (PTU)-induced memory impairment was investigated in juvenile rats. The rats were grouped into control, Hypo, Hypo-TQ5 and Hypo-TQ10. Propylthiouracil increased latency time in the Morris water maze test and decreased delay in ent...
Antioxidantes/farmacología,
Antitiroideos,
Reacción de Prevención/efectos de los fármacos,
Benzoquinonas/farmacología,
Lesiones Encefálicas/metabolismo,
Catalasa/análisis,
Modelos Animales de Enfermedad,
Hipocampo/efectos de los fármacos,
Hipotiroidismo/inducido químicamente,
Hipotiroidismo/complicaciones,
Discapacidades para el Aprendizaje/inducido químicamente,
Discapacidades para el Aprendizaje/tratamiento farmacológico,
Malondialdehído/análisis,
Aprendizaje por Laberinto/efectos de los fármacos,
Trastornos de la Memoria/inducido químicamente,
Trastornos de la Memoria/tratamiento farmacológico,
Óxido Nítrico/análisis,
Estrés Oxidativo/efectos de los fármacos,
Propiltiouracilo,
Ratas Wistar,
Superóxido Dismutasa/análisis
Unsal, Ayse Ipek Akyuz;
Basal, Yesim;
Birincioglu, Serap;
Kocaturk, Tolga;
Cakmak, Harun;
Unsal, Alparslan;
Cakiroz, Gizem;
Eliyatkın, Nüket;
Yukselen, Ozden;
Demirci, Buket.
ABSTRACT Purpose: To investigate the potential effects of chronic exposure to a nasal decongestant and its excipients on ocular tissues using an experimental rat model. Methods: Sixty adult male Wistar rats were randomized into six groups. The first two groups were control (serum physiologic) and Otriv...
Compuestos de Benzalconio/efectos adversos,
Modelos Animales de Enfermedad,
Ácido Edético/efectos adversos,
Ojo/efectos de los fármacos,
Ojo/patología,
Oftalmopatías/inducido químicamente,
Oftalmopatías/patología,
Imidazoles/efectos adversos,
Presión Intraocular,
Descongestionantes Nasales/efectos adversos,
Mucosa Nasal/efectos de los fármacos,
Mucosa Nasal/patología,
Distribución Aleatoria,
Ratas Wistar,
Índice de Severidad de la Enfermedad
Resumo: INTRODUÇÃO: O efeito deletério provocado pela isquemia e reperfusão do miocárdio durante a parada cardíaca apresenta-se como uma das principais causas da síndrome de baixo débito cardíaco no período pós-operatório. Neste sentido, a utilização de solução cardioplégica na indução...
