O conhecimento dos efeitos dos extratos naturais de plantas vem cada vez mais se mostrando um campo promissor. Extratos de Calendula officinalis, Capsicum annuum e Hamamelis virginiana apresentam propriedades analgésicas, anti-inflamatórias, antioxidantes e potencial antimicrobiano que deve ser aprofun...
ABSTRACT Objective: The objective was to evaluate the efficacy of gabapentin in the management of neuropathic pain in patients with keratoconus, who were treated with fast (10 minutes) epi-off corneal crosslinking (CXL). Methods: This was a prospective, double-blind, randomized study. The sample compri...
Queratocono/terapia,
Reactivos de Enlaces Cruzados/uso terapéutico,
Colágeno/metabolismo,
Riboflavina/uso terapéutico,
Rayos Ultravioleta,
Fármacos Fotosensibilizantes/uso terapéutico,
Córnea/metabolismo,
Dolor Postoperatorio/tratamiento farmacológico,
Dolor Ocular/tratamiento farmacológico,
Dimensión del Dolor,
Gabapentina/uso terapéutico,
Analgésicos/uso terapéutico,
Gabapentina/administración & dosificación,
Administración Oral,
Estudios Prospectivos,
Método Doble Ciego,
Encuestas y Cuestionarios
Silva, Juliana Figueira da;
Binda, Nancy Scardua;
Pereira, Elizete Maria Rita;
Lavor, Mário Sérgio Lima de;
Vieira, Luciene Bruno;
Souza, Alessandra Hubner de;
Rigo, Flávia Karine;
Ferrer, Hèlia Tenza;
Castro Júnior, Célio José de;
Ferreira, Juliano;
Gomez, Marcus Vinicius.
Phα1β is a neurotoxin purified from spider venom that acts as a high-voltage-activated (HVA) calcium channel blocker. This spider peptide has shown a high selectivity for N-type HVA calcium channels (NVACC) and an analgesic effect in several animal models of pain. Its activity was associated with a red...
Pain is a common symptom induced during envenomation by spiders and scorpions. Toxins isolated from their venom have become essential tools for studying the functioning and physiopathological role of ion channels, as they modulate their activity. In particular, toxins that induce pain relief effects can ...
Braga, Renan Marinho;
De Andrade, Humberto Hugo Nunes;
Neto, Humberto de Carvalho Aragão;
Da Cruz, Ryldene Marques Duarte;
Assis, Davidson Barbosa;
Cavalcante Silva, Luiz Henrique Agra;
Rodrigues Mascarenhas, Sandra;
Pordeus, Liana Clébia de Morais;
Quintans Júnior, Lucindo José;
De Almeida, Reinaldo Nóbrega.
Lippia pedunculosa Hayek (EOLp) presenta efectos tripanocidas y amebicidas. En este trabajo se estudia su aceite esencial en modelos experimentales de analgesia e inflamación una vez que la prevalencia del dolor en la población genera un gran sufrimiento y discapacidad, y los medicamentos que se usan c...
Abstract The objective of this study was to describe dental prescriptions of non-steroidal anti-inflammatory drugs (NSAID), opioids, and analgesics dispensed by the Brazilian National Health System (BNHS, SUS in Portuguese) of a Southeastern state from January to December 2017, and to analyze their assoc...
RESUMO Objetivo analisar a internalização do cuidado com o corpo pelo escolar com a doença falciforme com base na teoria do desenvolvimento de Vigotski e no conceito de cuidado de Collière. Método Estudo qualitativo com 15 escolares que convivem com a doença falciforme, acompanhados em ambulatór...
Investigación Cualitativa,
Dolor/tratamiento farmacológico,
Juego e Implementos de Juego,
Deshidratación,
Analgésicos/uso terapéutico,
Hidroxiurea/uso terapéutico,
Ácido Fólico/uso terapéutico,
Ingestión de Líquidos,
Anemia de Células Falciformes/prevención & control,
Autocuidado,
Ingestión de Alimentos
RESUMO Objetivo: identificar evidências científicas acerca dos fatores potenciais para o desenvolvimento de doença renal crônica em adolescentes e jovens. Método: revisão integrativa, utilizando uma ficha de seleção para extração dos dados das pesquisas nas bases de dados: Literatura Latino A...
Objective: Various glide path preparation techniques have been introduced, providing easiness to the practitioners. Recent literature has shown that glide path preparation influences the levels of postoperative pain occurrence in individuals receiving endodontic ...
ABSTRACT Purpose To explore the role and molecular mechanisms of neuroprotective effects of octreotide in alcohol-induced neuropathic pain. Methods Male Wistar rats were employed and were administered a chronic ethanol diet containing 5% v/v alcohol for 28 days. The development of neuropathic pain was ...
Analgésicos/farmacología,
Factor Neurotrófico Derivado del Encéfalo,
Cistationina betasintasa,
Etanol,
Sulfuro de Hidrógeno,
Hiperalgesia,
Factor 2 Relacionado con NF-E2,
Neuralgia/inducido químicamente,
Neuralgia/tratamiento farmacológico,
Octreótido/farmacología,
Ratas Wistar,
Factor de Necrosis Tumoral alfa,
Cistationina gamma-Liasa
