Results: 224

Differentiation of relapsing-remitting and secondary progressive multiple sclerosis: a magnetic resonance spectroscopy study based on machine learning

Arq. neuropsiquiatr; 78 (12), 2020
ABSTRACT Introduction: Magnetic resonance imaging (MRI) is the most important tool for diagnosis and follow-up in multiple sclerosis (MS). The discrimination of relapsing-remitting MS (RRMS) from secondary progressive MS (SPMS) is clinically difficult, and developing the proposal presented in this stud...

Esclerosis múltiple: reacciones adversas a medicamentos en pacientes bajo ley 20850, Hospital Regional de Talca
Multiple sclerosis: adverse drug reactions in patients under law 20850, Hospital Regional de Talca

Rev. méd. Maule; 36 (2), 2020
INTRODUCTION: Multiple sclerosis (MS) is a demyelinating disease of the central nervous system, which occurs in up to 85% of cases as relapsing remitting (RR), with episodes of neurological dysfunction partially forwarded. Its treatment in Chile is financially protected by the Explicit Health Guarantees ...

Restless legs syndrome/Willis-Ekbom disease in multiple sclerosis: a contributing factor for anxiety, disability, sleep disorder, and quality of life

Arq. neuropsiquiatr; 78 (11), 2020
ABSTRACT Background: Restless legs syndrome (RLS) is one of the most common and burdensome sleep disorders in the course of multiple sclerosis (MS). Objective: To evaluate common MS-related symptoms and consequences between groups with and without RLS and further assess the association of quality of li...

Medicamentos modificadores en esclerosis múltiple: esquemas terapéuticos actuales

La esclerosis múltiple (EM) es una enfermedad crónica, autoinmune y neurodegenerativa; que tiene como principal característica la desmielinización de los axones en el sistema nervioso. Los medicamentos modificadores de la enfermedad (MME) logran retrasar la aparición de los síntomas y modificar par...

Eficacia de la rehabilitación cognitiva en un paciente con esclerosis múltiple progresiva primaria

La esclerosis múltiple (EM) es una enfermedad inflamatoria crónica que cursa con la desmielinización y la neurodegeneración a nivel del sistema nervioso central. Existen tres tipos de EM en función de la progresión de la enfermedad, pero la mayor parte de los pacientes tienden a presentar déficits...

Dietary habits in a group of patients with multiple sclerosis are similar to those of healthy control subjects

Arq. neuropsiquiatr; 78 (10), 2020
ABSTRACT Background: Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system. Over time, patients with MS accumulate neurological disabilities. MS typically affects young adults and is associated with an inflammatory profile of cytokines and lymphocytes. If a patient were ...

Trastornos del sueño en pacientes con Esclerosis Múltiple: Fisiopatología y clínica

Resumen Los pacientes con Esclerosis múltiples tienen mayor tasa de trastornos del sueño que la población general. Los trastornos del sueño más prevalentes son: somnolencia diurna, insomnio, síndrome de piernas inquietas, trastornos respiratorios del sueño y narcolepsia. Los principales factores i...

Effects of Comorbid Fibromyalgia Syndrome on activities of daily living in multiple sclerosis patients

Arq. neuropsiquiatr; 78 (9), 2020
ABSTRACT Objective: To investigate the frequency of Comorbid Fibromyalgia Syndrome and its effects on quality of life and activities of daily living without any known psychiatric problem (schizophrenia or bipolar disorder) or severe disability, other than depression, in patients with multiple sclerosis...

Neuropsychiatric changes during the COVID-19 pandemic in multiple sclerosis patients

Arq. neuropsiquiatr; 78 (9), 2020
ABSTRACT Background: This study reported on a variety of psychological reactions related to anxiety, sleep quality, depression, fatigue, and quality of life in individuals with multiple sclerosis (MS), related to the Covid-19 quarantine experience. Objective: The aim of this study was to investigate ...

Management of central nervous system demyelinating diseases during the coronavirus disease 2019 pandemic: a practical approach

Arq. neuropsiquiatr; 78 (7), 2020
ABSTRACT Background: The novel coronavirus disease 2019 (COVID-19) pandemic poses a potential threat to patients with autoimmune disorders, including multiple sclerosis (MS) and neuromyelitis optica spectrum disorder (NMOSD). Such patients are usually treated with immunomodulatory or immunosuppressive ...