Results: 89

The role of oxidative stress in streptozotocin-induced diabetic nephropathy in rats

ABSTRACT Objective The objective of this study was to evaluate the role of oxidative stress in an experimental model of streptozotocin-induced diabetic nephropathy in rats. Materials and methods Wistar, adult, male rats were used in the study. Animals were divided in the following groups: Citrate (co...

Prevalencia de enfermedad renal crónica en pacientes con diabetes mellitus e hipertensión arterial en el Hospital Escandón
Prevalence of chronic kidney disease in patients with diabetes mellitus and arterial hypertension at Hospital Escandón

Salud pública Méx; 58 (3), 2016

Evaluation of biochemical and clinical markers of endothelial dysfunction and their correlation with urinary albumin excretion in patients with type 1 diabetes mellitus

ABSTRACT Objective Endothelial dysfunction (ED) plays an important role in the pathogenesis of diabetic nephropathy. The purpose of the study was to determine flow mediated endothelial dependent vasodilatation (FMD) measurements and serum soluble (s) endothelin-1 (ET-1), intercellular adhesion molecule...

Clinical outcomes of kidney transplants on patients with end-stage renal disease secondary to lupus nephritis, polycystic kidney disease and diabetic nephropathy

Colomb. med; 47 (1), 2016
Background: Patients with lupus nephritis could progress to endstage renal disease (10-22%); hence, kidney transplants should be considered as the treatment of choice for these patients. Objective: To evaluate the clinical outcomes after kidney transplants in patients with chronic kidney diseases seconda...

Endoplasmic reticulum stress and renal lesion in mice with combination of high-fat diet and streptozotocin-induced diabetes

Acta cir. bras; 31 (3), 2016
ABSTRACT PURPOSE : To investigate in the kidney the pathologic changes and expression of GRP78 and CHOP in the Kunming (KM) mice with combination of high-fat diet and streptozotocin-induced diabetes. METHODS : Sixty two male KM mice were randomly divided into a normal control (NC) group (n=20) and a hi...

Mecanismos de inducción de la matriz extracelular en la nefropatía diabética
Mechanisms of induction of the extracellular matrix in diabetic nephropathy

Rev. cuba. endocrinol; 26 (3), 2015
La nefropatía diabética es una complicación grave en la diabetes mellitus. Sus principales cambios morfológicos típicos se deben al aumento de la cantidad de proteínas de la matriz extracelular. Los productos finales de glicación avanzada, resultado de la hiperglucemia, estimulan la producción de...

Relação dos polimorfismos funcionais -509C>t e 869T>C no gene do TGFβ1 com a retinopatia e nefropatia diabéticas em pacientes com diabetes mellitus tipo 2

Rev. AMRIGS; 56 (3), 2012
Introdução: O fator de crescimento transformante beta-1 (TGFβ1) é uma citocina multifuncional que regula a proliferação, a diferenciação e a formação da matriz extracelular de vários tipos de células. Existem evidências de que os polimorfismos -509C>T e 869T>C no gene do TGFβ1 alteram a sua...

Asociación de la microalbuminuria con la disfunción ventricular izquierda en personas normotensas con diabetes mellitus tipo 1
Microalbuminuria and its association with left ventricular dysfunction in normotensive subjects presenting with type 1 diabetes mellitus

Rev. cuba. endocrinol; 20 (1), 2009
La disfunción ventricular izquierda es una complicación frecuente en las personas con diabetes mellitus 1. Es objetivo del trabajo determinar si la excreción urinaria de albúmina se asocia a la presencia de disfunción ventricular izquierda en personas normotensas con diabetes mellitus 1 de largo tie...