Results: 151

Association of serum levels of C-reactive protein with CRP-717 T/C polymorphism and viremia in HCV and HBV carriers

Abstract INTRODUCTION: The present study investigated the association of the rs2794521 polymorphism in the CRP gene in individuals with chronic hepatitis B and C, correlating it with markers of hepatic inflammation, fibrosis scores, viral load, and plasma protein levels. METHODS: The study analyzed 185...

The role of high sensitive C-reactive protein and histopathological evaluation in chronic gastritis patients with or without Helicobacter pylori infection

Acta cir. bras; 34 (3), 2019
Abstract Purpose: To evaluate serum levels of high-sensitivity C-reactive protein (hs-CRP) in chronic gastritis patients to predict Helicobacter pylori (HP) infection, inflammatory activity, and precancerous lesions. Methods: A total of 811 patients with upper gastrointestinal symptoms and histopatho...

Lipid profile and statin use in critical care setting: implications for kidney outcome

Einstein (Säo Paulo); 17 (3), 2019
ABSTRACT Objective: To determine whether pre-hospital statin use is associated with lower renal replacement therapy requirement and/or death during intensive care unit stay. Methods: Prospective cohort analysis. We analyzed 670 patients consecutively admitted to the intensive care unit of an academic t...

Effects of natural aging and gender on pro-inflammatory markers

Braz. j. med. biol. res; 52 (9), 2019
The term inflammaging is now widely used to designate the inflammatory process of natural aging. During this process, cytokine balance is altered, presumably due to the loss of homeostasis, thus contributing to a greater predisposition to disease and exacerbation of chronic diseases. The aim of the study...

Diagnostic value of circulating lncRNA ANRIL and its correlation with coronary artery disease parameters

Braz. j. med. biol. res; 52 (8), 2019
This study aimed to detect the expression of the long non-coding RNA (lncRNA) antisense non-coding RNA in the INK4 locus (ANRIL) and evaluate its correlation with disease risk, stenosis degree, inflammation, as well as overall survival (OS) in coronary artery disease (CAD) patients. A total of 230 patien...

The effect of nonsurgical periodontal therapy on hepcidin and on inflammatory and iron marker levels

Abstract Serum hepcidin levels may increase in response to infection and inflammation. The present study investigated the effect of nonsurgical periodontal therapy (NSPT) on levels of serum hepcidin, inflammatory markers, and iron markers. An interventional study was conducted on 67 patients (age 30-65 y...

Altered peripheral lymphocyte subsets in untreated systemic lupus erythematosus patients with infections

Braz. j. med. biol. res; 52 (4), 2019
The leading cause of death in systemic lupus erythematosus (SLE) patients is infection. The objective of this study was to evaluate the distribution of lymphocyte subsets in untreated SLE patients with infections. This was a cross-sectional study. Data from January 2017 to May 2018 were collected. Flow c...

Effects of a dietary supplement on inflammatory marker expression in middle-aged and elderly hypertensive patients

Clinics; 74 (), 2019
OBJECTIVES: We aimed to explore the effects of diet on the inflammatory response in middle-aged and elderly people with hypertension. METHODS: Thirty overweight or obese patients with stage one hypertension (age range, 45-75 years) were allocated to either the intervention or control group (n=15 per gro...

Factors associated with metabolic syndrome in older adults: a population-based study

Rev. bras. enferm; 72 (supl.2), 2019
ABSTRACT Objective: To estimate the prevalence of the metabolic syndrome and clusters of its components and to identify possible associated factors in older adults. Method: Cross-sectional and population-based study, involving 271 older people. We collected sociodemographic, behavioral, clinical, bioch...

Therapeutic effect of adenosine on experimentally induced acute ulcerative colitis model in rats

Acta cir. bras; 34 (12), 2019
Abstract Purpose To examine the therapeutic effect of external adenosine on an acetic acid-induced acute ulcerative colitis model in rats. Methods Thirty male mature rats were divided into three groups as control, acute colitis (AC) and AC+adenosine group (AC+AD). AC was induced by rectal administrat...