Results: 179

Dengue, zika, chikungunya y el desarrollo de vacunas
Dengue, zika, chikungunya and the development of vaccines

Medicina (B.Aires); 78 (1), 2018
Dengue (DENV), zika (ZIKV) y chikungunya (CHIKV), tres arbovirosis transmitidas por mosquitos Aedes, se han propagado en las últimas décadas en zonas tropicales y subtropicales húmedas. El dengue es epidémico en áreas subtropicales de la Argentina. Después de la infección por DENV hay inmunidad du...

Pathogen-insect interaction candidate molecules for transmission-blocking control strategies of vector borne diseases

Salud pública Méx; 60 (1), 2018
Abstract: Objective: To analyze the current knowledge of pathogen-insect interactions amenable for the design of molecular-based control strategies of vector-borne diseases. Materials and methods: We examined malaria, dengue, and Chagas disease pathogens and insect molecules that participate in inter...

Dengue virus infection induces chromatin remodeling at locus AAEL006536 in the midgut of Aedes aegypti

Salud pública Méx; 60 (1), 2018
Abstract: Objective: To identify and characterize Aedes aegypti's AAEL006536 gene proximal upstream cis-regulatory sequences activated by dengue virus infection. Materials and methods: A. aegypti Rockefeller strain mosquitoes were blood fed or infected with dengue virus 2. Open chromatin profiling was...

Transmission of dengue virus from deceased donors to solid organ transplant recipients: case report and literature review

Braz. j. infect. dis; 22 (1), 2018
ABSTRACT Dengue fever is a vector-transmitted viral infection. Non-vectorial forms of transmission can occur through organ transplantation. We reviewed medical records of donors and recipients with suspected dengue in the first post-transplant week. We used serologic and molecular analysis to confirm the...

Estudo de mutações nas proteínas virais E, NS3 e NS4B no genoma do vírus vacinal da Febre Amarela 17D

Resumo: A Febre Amarela (FA) é uma doença infecciosa não contagiosa, causada por um arbovírus e objeto de preocupação sanitária mundial. A principal medida de controle é a vacinação com o vírus atenuado da FA, cepa 17D, que é capaz de induzir resposta imune protetora a longo prazo com adminis...

Prevalência sorológica de infecções por dengue, zika e chikungunya vírus em gestantes atendidas numa maternidade pública, no município de Nova Iguaçu, Baixada Fluminense

Há décadas, a dengue constitui um enorme desafio em saúde pública no Brasil e no mundo. A este desafio, sobreveio a emergência de duas outras arboviroses, também transmitidas por mosquitos do gênero Aedes: a zika e a febre chikungunya. Epidemias em diversos países do continente americano, a parti...

Improved reverse transcription-polymerase chain reaction assay for the detection of flaviviruses with semi-nested primers for discrimination between dengue virus serotypes and Zika virus

Mem. Inst. Oswaldo Cruz; 113 (5), 2018
BACKGROUND The genus Flavivirus includes a variety of medically important viruses, including dengue virus (DENV) and Zika virus (ZIKV), which are most prevalent in Brazil. Because the clinical profile of patients affected by different DENV serotypes or ZIKV may be similar, the development of new methods...

Co-infección por los virus del dengue y chikungunya: revisión narrativa

Rev. chil. infectol; 35 (6), 2018
Resumen Introducción: Los virus del dengue y chikungunya son transmitidos por la hembra de los mosquitos Aedes aegypti y Aedes albopictus, ampliamente distribuidos en zonas tropicales y subtropicales, lo que facilita la co-infección. Objetivo: Determinar la magnitud, la distribución geográfica y el...

Potential role of dengue virus, chikungunya virus and Zika virus in neurological diseases

Mem. Inst. Oswaldo Cruz; 113 (11), 2018
This study showed that laboratory markers of recent infection by dengue, Zika or chikungunya arboviruses were detected in the biological samples of approximately one-third of patients with encephalitis, myelitis, encephalomyelitis or Guillain-Barré syndrome, in a surveillance programme in Piauí state, ...

First detection of dengue virus in the saliva of immunocompetent murine model

Mem. Inst. Oswaldo Cruz; 113 (4), 2018
The lack of an experimental animal model for the study of dengue pathogenesis is a limiting factor for the development of vaccines and drugs. In previous studies, our group demonstrated the susceptibility of BALB/c mice to infection by dengue virus (DENV) 1 and 2, and the virus was successfully isolated ...